ChemicalBook > CAS DataBase List > 2-BROMO-5-NITROPYRIDIN-4-AMINE

2-BROMO-5-NITROPYRIDIN-4-AMINE

Product Name
2-BROMO-5-NITROPYRIDIN-4-AMINE
CAS No.
84487-15-0
Chemical Name
2-BROMO-5-NITROPYRIDIN-4-AMINE
Synonyms
4-AMino-2-broMo-5-nitropy...;2-BROMO-5-NITROPYRIDIN-4-AMINE;2-broMo-5-nitropyridin-4-aMino;2-BroMo-5-nitro-4-pyridinaMine;4-Amino-2-bromo-5-nitropyridine;4-Pyridinamine, 2-bromo-5-nitro-;(2-Bromo-5-nitropyridin-4-yl)amine;4-Amino-2-bromo-5-nitropyridine 95%
CBNumber
CB62455765
Molecular Formula
C5H4BrN3O2
Formula Weight
218.01
MOL File
84487-15-0.mol
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2-BROMO-5-NITROPYRIDIN-4-AMINE Property

Boiling point:
396.3±37.0 °C(Predicted)
Density 
1.929±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
0.79±0.42(Predicted)
Appearance
Light yellow to light brown Solid
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Safety

HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B673880
Product name
2-bromo-5-nitropyridin-4-amine
Packaging
100mg
Price
$65
Updated
2021/12/16
SynQuest Laboratories
Product number
4H55-9-33
Product name
4-Amino-2-bromo-5-nitropyridine
Packaging
100mg
Price
$101
Updated
2021/12/16
SynQuest Laboratories
Product number
4H55-9-33
Product name
4-Amino-2-bromo-5-nitropyridine
Packaging
250mg
Price
$159
Updated
2021/12/16
AK Scientific
Product number
Y4181
Product name
2-Bromo-5-nitropyridin-4-amine
Packaging
250mg
Price
$231
Updated
2021/12/16
Matrix Scientific
Product number
115675
Product name
4-Amino-2-bromo-5-nitropyridine
Purity
95+%
Packaging
1g
Price
$1019
Updated
2021/12/16
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2-BROMO-5-NITROPYRIDIN-4-AMINE Chemical Properties,Usage,Production

Synthesis

4487-57-4

84487-15-0

Step 1. 2,4-Dibromo-5-nitropyridine (3.67 g) was dissolved in tetrahydrofuran (THF, 150 mL) under the protection of nitrogen, followed by the addition of methanol solution of ammonia (2 M) and triethylamine (5 mL) sequentially. The reaction mixture was stirred at room temperature for 50 hours. Upon completion of the reaction, the reaction mixture was concentrated, the residue was dissolved in ethyl acetate (EtOAc), filtered through a silica gel pad, and the filtrate was concentrated under vacuum to afford 2-bromo-5-nitro-4-aminopyridine in 95% yield.

References

[1] ACS Medicinal Chemistry Letters, 2015, vol. 6, # 1, p. 42 - 46
[2] Patent: WO2005/37197, 2005, A2. Location in patent: Page/Page column 102
[3] Patent: WO2005/37197, 2005, A2. Location in patent: Page/Page column 102

2-BROMO-5-NITROPYRIDIN-4-AMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-BROMO-5-NITROPYRIDIN-4-AMINE Suppliers

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View Lastest Price from 2-BROMO-5-NITROPYRIDIN-4-AMINE manufacturers

Career Henan Chemical Co
Product
2-BROMO-5-NITROPYRIDIN-4-AMINE 84487-15-0
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2019-12-19

84487-15-0, 2-BROMO-5-NITROPYRIDIN-4-AMINERelated Search:


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