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2-Bromo-4-methoxypyridine

Product Name
2-Bromo-4-methoxypyridine
CAS No.
89488-29-9
Chemical Name
2-Bromo-4-methoxypyridine
Synonyms
bromo-4-methoxypyridine;2-Bromo-4-methoxypyridine;Pyridine,2-bromo-4-methoxy-;2-Bromo-4-methoxypyridine 98%;2-Bromo-4-methoxypyridine ISO 9001：2015 REACH
CBNumber
CB1971743
Molecular Formula
C6H6BrNO
Formula Weight
188.02
MOL File
89488-29-9.mol
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2-Bromo-4-methoxypyridine Property

Boiling point:
120-121 °C(Press: 10 Torr)
Density 
1.530±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
pka
2.10±0.10(Predicted)
form 
solid
color 
Yellow
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Safety

HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

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N-Bromosuccinimide Price

Apolloscientific
Product number
OR61413
Product name
2-Bromo-4-methoxypyridine
Purity
98%
Packaging
1g
Price
$37
Updated
2021/12/16
SynQuest Laboratories
Product number
4H56-9-Z8
Product name
2-Bromo-4-methoxypyridine
Packaging
1g
Price
$40
Updated
2021/12/16
AK Scientific
Product number
J90714
Product name
2-Bromo-4-methoxypyridine
Packaging
5g
Price
$124
Updated
2021/12/16
Apolloscientific
Product number
OR61413
Product name
2-Bromo-4-methoxypyridine
Purity
98%
Packaging
5g
Price
$125
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB55589
Product name
2-Bromo-4-methoxypyridine
Packaging
1g
Price
$125
Updated
2021/12/16
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2-Bromo-4-methoxypyridine Chemical Properties,Usage,Production

Uses

2-Bromo-4-methoxypyridine acts as a reagent for the synthesis of biarylsulfonamide CCR9 inhibitors for inflammatory bowel diseases.

Synthesis

124-41-4

22918-01-0

89488-29-9

The general procedure for the synthesis of 2-bromo-4-methoxypyridine from sodium methanol and 2-bromo-4-chloropyridine was as follows: sodium methanol (0.35 g, 6.48 mmol) was added to a solution of 2-bromo-4-chloropyridine (1.0 g, 5.2 mmol) in dimethyl sulfoxide (DMSO, 10 mL). After the addition was completed, the reaction mixture was stirred at 120 °C for 24 hours. After completion of the reaction, the mixture was cooled to room temperature and extracted with ethyl acetate (EtOAc). The organic layers were combined and dried over anhydrous sodium sulfate (Na2SO4) and subsequently concentrated under reduced pressure. Purification of the residue by preparative high performance liquid chromatography (HPLC) gave 2-bromo-4-methoxypyridine (0.25 g, 25% yield) as a colorless oil. The mass spectrometry (MS) electrospray ionization (ESI) calculated value was 189 for C6H6BrNO [M + H]+ and the measured value was 189.

References

[1] Patent: WO2014/74422, 2014, A1. Location in patent: Paragraph 00162

2-Bromo-4-methoxypyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Bromo-4-methoxypyridine Suppliers

China 139 China Hong Kong 1 Germany 1 India 4 Switzerland 1 United Kingdom 2 United States 12 Global 160
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
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China
ProdList
96815
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3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
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China
ProdList
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Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
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Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
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China
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JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
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sales@jingyan-chemical.com
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China
ProdList
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Jia Xing Isenchem Co.,Ltd
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0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
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Accela ChemBio Co.,Ltd.
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021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
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China
ProdList
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Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9883
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ZEROSCHEM.CO.,LTD.
Tel
10-61256048 13810278579
Fax
+86 10 61256049
Email
sales@zeroschem.com
Country
China
ProdList
1370
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Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
15883
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64
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View Lastest Price from 2-Bromo-4-methoxypyridine manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
2-Bromo-4-methoxypyridine 89488-29-9
Price
US $9.80/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 tons
Release date
2024-11-27
Dideu Industries Group Limited
Product
2-Bromo-4-methoxypyridine 89488-29-9
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-10-27
Career Henan Chemical Co
Product
2-Bromo-4-methoxypyridine 89488-29-9
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000kgs
Release date
2020-01-02

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  • bromo-4-methoxypyridine
  • Pyridine,2-bromo-4-methoxy-
  • 2-Bromo-4-methoxypyridine 98%
  • 2-Bromo-4-methoxypyridine ISO 9001：2015 REACH
  • 89488-29-9
  • Pyridine
  • Heterocyclic Series
  • blocks
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