ChemicalBook > CAS DataBase List > 5-Amino-2-fluorophenol

5-Amino-2-fluorophenol

Product Name
5-Amino-2-fluorophenol
CAS No.
100367-48-4
Chemical Name
5-Amino-2-fluorophenol
Synonyms
5-Amino-2-fluorophenol;Phenol, 5-amino-2-fluoro-;4-Fluoro-3-hydroxyaniline;5-Amino-2-fluorophenol,97%;5-Amino-2-fluorophenol 95+%;2-(1,1-dimethyl-2-hydroxyethyl)-1,3-dioxolane
CBNumber
CB62527835
Molecular Formula
C6H6FNO
Formula Weight
127.12
MOL File
100367-48-4.mol
More
Less

5-Amino-2-fluorophenol Property

Melting point:
156-158℃
Boiling point:
255.3±20.0 °C(Predicted)
Density 
1.347±0.06 g/cm3(Predicted)
storage temp. 
2-8°C, protect from light, stored under nitrogen
form 
Solid
pka
8.76±0.10(Predicted)
color 
White to yellow
More
Less

Safety

HazardClass 
IRRITANT
HS Code 
2922290090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More
Less

N-Bromosuccinimide Price

TRC
Product number
A630993
Product name
5-Amino-2-fluorophenol
Packaging
50mg
Price
$45
Updated
2021/12/16
TRC
Product number
A630993
Product name
5-Amino-2-fluorophenol
Packaging
100mg
Price
$90
Updated
2021/12/16
Apolloscientific
Product number
PC8698
Product name
5-Amino-2-fluorophenol
Purity
95+%
Packaging
1g
Price
$114
Updated
2021/12/16
Matrix Scientific
Product number
056369
Product name
5-Amino-2-fluorophenol
Purity
>95%
Packaging
500mg
Price
$125
Updated
2021/12/16
Matrix Scientific
Product number
056369
Product name
5-Amino-2-fluorophenol
Purity
>95%
Packaging
1g
Price
$157
Updated
2021/12/16
More
Less

5-Amino-2-fluorophenol Chemical Properties,Usage,Production

Uses

5-Amino-2-fluorophenol is used as synthetic building block.

Synthesis

64465-53-8

100367-48-4

Example 9A Step 1: 4-Fluoro-3-methoxyaniline (2.0 g, 14.2 mmol) was dissolved in dichloromethane (20 mL) at 0 °C and a dichloromethane solution of 1.0 M boron tribromide (40 mL) was slowly added dropwise. The reaction mixture was stirred at 0 °C, followed by gradual warming to room temperature and continued stirring overnight. Upon completion of the reaction, the reaction was quenched by the addition of methanol, followed by removal of the solvent under reduced pressure. Water was added to the residue, which was alkalized with saturated sodium bicarbonate solution to pH neutral and then extracted with ethyl acetate. The organic phase was washed with saturated brine, dried over anhydrous magnesium sulfate and concentrated under reduced pressure to give 5-amino-2-fluorophenol as a white solid (1.3 g, 73% yield). The product was characterized by 1H NMR (300 MHz, DMSO-d6): δ 9.26 (s, 1H), 6.81 (dd, 1H), 6.34 (dd, 1H), 6.04 (dd, 1H), 4.63 (br, 2H).

References

[1] Patent: WO2009/117080, 2009, A1. Location in patent: Page/Page column 171
[2] Patent: US2002/198194, 2002, A1
[3] Patent: WO2011/119704, 2011, A1. Location in patent: Page/Page column 45

5-Amino-2-fluorophenol Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

5-Amino-2-fluorophenol Suppliers

China 48 United Kingdom 1 United States 5 Global 54
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14101
Advantage
59
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18729
Advantage
57
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
Advantage
57
Wuhan ariel chemical Co., LTD.
Tel
18986259541
Fax
027-87840182
Email
sales@3stc.com
Country
China
ProdList
3764
Advantage
58
Shanghai Jian Chao Chemical Technology Co., Ltd.
Tel
150-2103-5486 18017383231
Fax
qq：2817624287
Email
983544897@qq.com
Country
China
ProdList
9342
Advantage
55
Jalor-Chem co.,LTD
Tel
0510-0510-86396359 13382276200
Email
sales@jalor-chem.com
Country
China
ProdList
996
Advantage
56
SuZhou ShiYa Biopharmaceuticals, Inc.
Tel
0512-0512-52358471 17715136450
Fax
05125235 6881
Email
sales@shiyabiopharm.com
Country
China
ProdList
12127
Advantage
58
ShangHai Angti Biotechnology Co., Ltd.
Tel
13764913901
Fax
-
Email
info@angtibio.com
Country
China
ProdList
4984
Advantage
55
Shanghai Haozhixiang Biotechnology Co., Ltd
Tel
526763801 13301653310
Fax
+86-21-51619052
Email
526763801@qq.com
Country
China
ProdList
9287
Advantage
55
Guangzhou Jhd Chemical Reagent Co., Ltd.
Tel
020-84383047
Fax
020-84380294
Email
sales@jhd.com.cn
Country
China
ProdList
9186
Advantage
65
Hangzhou Molcore Biopharmatech Co.,Ltd
Tel
400-711-5280 86-571-81025280
Fax
86-571-85806285
Email
sales@molcore.com
Country
China
ProdList
9967
Advantage
58
Aikon International Limited
Tel
025-58859352 18068836627
Fax
02557626880
Email
sales01@aikonchem.com
Country
China
ProdList
16027
Advantage
58
Henan Alfachem Co.,Ltd.
Tel
0371-55051623 18137891487
Fax
QQ：2853979817
Email
2853979817@qq.com
Country
China
ProdList
9992
Advantage
58
Shanghai SPAR pharmaceutical technology co., LTD
Tel
021-000000
Email
admin@jingshipharmatech.com
Country
China
ProdList
9853
Advantage
58
Fuxin Crest Biotechnology Co. Ltd.
Tel
13062833949
Fax
QQ: 2073772974
Email
fred.wen@crcorporation.cn
Country
China
ProdList
853
Advantage
58
Henan Lien Chemical Products Co., Ltd.
Tel
03716091-9097 13383857418
Fax
03716091-9097
Email
1520689222@qq.com
Country
China
ProdList
4863
Advantage
58
Henan Alfa Chemical Co., Ltd
Tel
+8615838112936
Email
alfa10@alfachem.cn
Country
China
ProdList
12921
Advantage
58
Hefei TNJ Chemical Industry Co.,Ltd.
Tel
+86-0551-65418684 +8618949823763
Fax
0086-551-65418684
Email
sales@tnjchem.com
Country
China
ProdList
25356
Advantage
58
Career Henan Chemica Co
Tel
+86-0371-86658258 +8613203830695
Fax
0371-86658258
Email
laboratory@coreychem.com
Country
China
ProdList
30229
Advantage
58
Wuxi Kehua Biological Technology Co., Ltd.
Tel
0510-86838766 13636419861
Email
2258830676@qq.com
Country
China
ProdList
5044
Advantage
58
career henan chemical co
Tel
+86-0371-86658258 +8613203830695
Fax
0086-371-86658258
Email
factory@coreychem.com
Country
China
ProdList
29798
Advantage
58
Nanjing shengyilai Chemical Co., Ltd
Tel
19951936396
Email
3158688292@qq.com
Country
China
ProdList
4856
Advantage
58
Fuxin Pharmaceutical
Tel
+86-021-021-50872116 +8613122107989
Email
contact@fuxinpharm.com
Country
China
ProdList
10000
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44894
Advantage
58
Shandong Territorial sea Biological Technology Co., LTD
Tel
15092083467
Email
18660263263@163.com
Country
China
ProdList
2811
Advantage
58
Shanghai Sunway Pharmaceutical Technology Co.,Ltd.
Tel
021-51816796-820 13611835272
Fax
021-5161 3951
Email
sales2@sunwaypharm.com
Country
China
ProdList
44119
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 4008210725
Email
malulu@leyan.com
Country
China
ProdList
40000
Advantage
58
PharmaBlock Sciences (Nanjing), Inc.
Tel
4000255188
Fax
025 86918232
Email
sales_china@pharmablock.com
Country
China
ProdList
10000
Advantage
58
ChemeGen
Tel
18818260767
Fax
QQ 3610331285
Email
2625930290@qq.com
Country
China
ProdList
6973
Advantage
58
Bide Pharmatech Ltd.
Tel
400-1647117 13681763483
Email
product02@bidepharm.com
Country
China
ProdList
59936
Advantage
58
Qi Qi hang Biotechnology Co., Ltd.
Tel
15870833005
Email
2232044025@qq.com
Country
China
ProdList
8206
Advantage
58
Zhengzhou Lingzhiyue Technology Co., LTD
Tel
+86-0371-55074660
Email
Lingzhiyue@aliyun.com
Country
China
ProdList
4739
Advantage
58
Henan Dowon Chemical Technology Co., Ltd.
Tel
16696119288
Email
779113375@qq.com
Country
China
ProdList
7236
Advantage
58
Shaanxi Didu New Material Co., Ltd
Tel
029-81145920 17391631969
Email
1046@dideu.com
Country
China
ProdList
9996
Advantage
58
Shanghai Jieshikai Biotechnology Co. , Ltd.
Tel
021-57520305 13795461237
Email
zhuruyan@jskchem.com
Country
China
ProdList
49234
Advantage
58
PharmaBlock Sciences (Nanjing), Inc.
Tel
4000255188
Email
sales@pharmablock.com
Country
China
ProdList
7268
Advantage
58
Nanjing Bic Biotechnology Co., Ltd
Tel
025-58906079 17352406906
Email
sales@bicbiotech.com
Country
China
ProdList
5996
Advantage
58
Nanjing Shizhou Biology Technology Co.,Ltd
Tel
17301488900
Fax
025-85560043
Email
judy.xia@synzest.com
Country
China
ProdList
12582
Advantage
58
Shaanxi Imano Pharmaceutical Technology Co., Ltd
Tel
15683496527 18220923020
Email
630940531@qq.com
Country
China
ProdList
490
Advantage
58
Shanghai Shengxiu Biotechnology Co., Ltd.
Tel
13761144602
Email
3896578657@qq.com
Country
China
ProdList
4483
Advantage
58
Suzhou ARTK Medchem Co., Ltd.
Tel
+86-512-68323658 +86-18168183658
Email
sales1@artkmedchem.com
Country
China
ProdList
39002
Advantage
58
Nanjing Bicbiotechnology Co., Ltd
Tel
+86-2552131256 +86-18251840740
Email
sales@bicbiotech.com
Country
China
ProdList
5994
Advantage
58
Zhengzhou Lingzhiyue Technology Co., Ltd
Tel
+86-0371-55074660 +8613523716970
Email
Lingzhiyue@aliyun.com
Country
China
ProdList
3145
Advantage
58
Nanjing Doge Biomedical Technology Co., Ltd
Tel
+86-25-58227606 +86-15305155328
Email
sales@dogechemical.com
Country
China
ProdList
4128
Advantage
58
Aromsyn Co., Ltd.
Tel
+86-0571-85585865 +8613336024896
Email
CB@aromsyn.com
Country
China
ProdList
19183
Advantage
58
Changzhou Ansciep Chemical Co., Ltd.
Tel
+86 519 86305871
Fax
+86 519 86305879
Email
sales@ansciepchem.com
Country
CHINA
ProdList
4241
Advantage
58
Absin Bioscience Inc.
Tel
--
Fax
--
Email
chenjw@absin.cn
Country
CHINA
ProdList
6208
Advantage
58

100367-48-4, 5-Amino-2-fluorophenolRelated Search:

6-Chloro-3-fluoro-2-nitro-phenol 4-BROMO-2,3-DIMETHYLPHENOL 6-bromo-3-fluoro-2-nitrophenol 2,6-Dimethyl-4-aminophenol Acetic acid 4-chloro-3-Methylphenyl ester 3-broMo-5-iodo-phenol 2-hydroxy-4-Methoxytoluene 4-IODO-2-METHOXYPHENOL Phenol, 4-amino-2-chloro-6-fluoro- 3-AMINO-5-CHLOROPHENOL 3-Bromo-4,5-dimethylphenol 3-FLUORO-5-METHOXY-PHENOL 4-BROMO-2-FLUORO-5-NITROPHENOL

  • 4-Fluoro-3-hydroxyaniline
  • 5-Amino-2-fluorophenol 95+%
  • 5-Amino-2-fluorophenol
  • 2-(1,1-dimethyl-2-hydroxyethyl)-1,3-dioxolane
  • Phenol, 5-amino-2-fluoro-
  • 5-Amino-2-fluorophenol,97%
  • 100367-48-4