3-Methylpicolinonitrile

Product Name: 3-Methylpicolinonitrile
CAS No.: 20970-75-6
Chemical Name: 3-Methylpicolinonitrile
Synonyms: 2-CYANO-3-METHYLPYRIDINE;2-CYANO-3-PICOLINE;3-METHYL-2-PYRIDINECARBONITRILE;2-Cyanopicoline;2-Cyano-3-methyL;2-Cyano-B-picoline;3-Methylpicolinonitr;Cyano-3-methylpyridine;3-METHYLPICOLINONITRILE;2-cyno,3-Methyl pyridine
CBNumber: CB6256294
Molecular Formula: C7H6N2
Formula Weight: 118.14
MOL File: 20970-75-6.mol

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3-Methylpicolinonitrile Property

Melting point:: 83-87 °C(lit.)
Boiling point:: 141°C 38mm
Density: 1.1151 (rough estimate)
refractive index: 1.5500 (estimate)
Flash point:: 115°C
storage temp.: Inert atmosphere,Room Temperature
solubility: Chloroform (Slightly), Methanol (Slightly)
pka: -0.03±0.10(Predicted)
form: Crystalline Powder
color: Light beige
BRN: 112001
CAS DataBase Reference: 20970-75-6(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-36/37
RIDADR: 3439
WGK Germany: 3
HazardClass: 6.1
PackingGroup: III
HS Code: 29333999

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H301Toxic if swalloed

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 512737
Product name: 3-Methylpicolinonitrile
Purity: 98%
Packaging: 5g
Price: $49.7
Updated: 2023/01/07

TCI Chemical

Product number: C1410
Product name: 2-Cyano-3-methylpyridine
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $16
Updated: 2025/07/31

TCI Chemical

Product number: C1410
Product name: 2-Cyano-3-methylpyridine
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $37
Updated: 2025/07/31

TRC

Product number: M332970
Product name: 3-Methylpicolinonitrile
Packaging: 5g
Price: $45
Updated: 2021/12/16

Frontier Specialty Chemicals

Product number: JK243599
Product name: 2-Cyano-3-methylpyridine
Purity: 98%
Packaging: 5g
Price: $46
Updated: 2021/12/16

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3-Methylpicolinonitrile Chemical Properties,Usage,Production

Chemical Properties

light beige crystalline powder

Uses

3-Methylpicolinonitrile is a useful chemical reagent. It has been used in the synthesis of, triazolo[1,5-c]pyrimidines as potential antiasthma agents; ?s-tetrazine derivatives as anti-tumor agents.

Synthesis

1003-73-2

20970-75-6

II-1-1: Synthesis of 2-cyano-3-methylpyridine 10.9 g (0.1 mol) of 3-methylpyridine-N-oxide was mixed with 12.6 g (0.1 mol) of dimethyl sulfate and the reaction was stirred at 70-75°C for 2 hours. Subsequently, a solution prepared from 13.0 g (0.2 mol) potassium cyanide dissolved in 10-40 mL of water was slowly added dropwise to the reaction system while maintaining stirring. After the dropwise addition was completed, the reaction mixture was continued to be stirred at the same temperature for 1 hour and then at room temperature for another 1 hour. Upon completion of the reaction, it was diluted with 150 mL of water and extracted with dichloromethane. The organic phases were combined, dried with anhydrous sodium sulfate and concentrated under reduced pressure. The resulting crude product was purified by silica gel column chromatography (eluent ratio: ethyl acetate/hexane = 2:8 to 3:7, 2:8 for the second time), and finally recrystallized from hexane to give 2.20 g of colorless solid product in 18.6% yield. The melting point of the product was 82.5-83.5 °C. IR (KBr, cm-1): 2210, 1560.

References

[1] Patent: US5219847, 1993, A
[2] Chemical and Pharmaceutical Bulletin, 1959, vol. 7, p. 925,928

3-Methylpicolinonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Methylpicolinonitrile Suppliers

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View Lastest Price from 3-Methylpicolinonitrile manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 3-Methylpicolinonitrile 20970-75-6
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-12-02

Shaanxi Dideu Medichem Co. Ltd

Product: 3-Methylpicolinonitrile 20970-75-6
Price: US $1.10/g
Min. Order: 1g
Purity: 99.0% min
Supply Ability: 100 tons min
Release date: 2021-05-13

Honest Joy Holdings Limited

Product: 2-Cyano-3-methylpyridine 20970-75-6
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99.1%
Supply Ability: 100 tons
Release date: 2022-01-26

20970-75-6, 3-MethylpicolinonitrileRelated Search:

4-Methylpyridine 2,4,6-Collidine 2,6-Lutidine 3-Picoline Azamethiphos Trimethylsilyl cyanide 2-Cyanopyridine 2-CYANOPYRIDINE-3-CARBOXYLIC ACID 3-CYANO-5-METHYLPYRIDINE 3-[2-(3-Chlorophenyl)ethyl]-2-pyridinecarbonitrile 5-hydroxy-3-methylpicolinonitrile 5-Methylpicolinonitrile 2-Chloro-4-methylpyridine-3-carbonitrile 2-Chloro-6-methyl-3-pyridinecarbonitrile 3-Cyano-2-methylpyridine 3-Cyano-2,6-dihydroxy-4-methylpyridine 5-CYANO-2-METHYLPYRIDINE 4-Methylpicolinonitrile

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2-Cyano-3-picoline 3-Methylpicolinonitrile

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2-CYANO-3-PICOLINE

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3-METHYLPICOLINONITRILE

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3-METHYL-2-PYRIDINECARBONITRILE

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2-CYANO-3-METHYLPYRIDINE 3-METHYL-PYRIDINE-2-CARBONITRILE

2-CYANO-3-METHYLPYRIDINE (2-CYANO-3-PICOLINE)

2-Cyano-3-Methylpyridine 99%

2-Pyridinecarbonitrile, 3-methyl-

2-Cyano-3-methylpyridine ,98%

2-Cyano-3-methylpyridine (3-Methylpicolinonitrile)

2-Cyanopicoline

3-Methylpyridin-2-carbonitril

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2-Hydroxy-6-bromopyridine

3-Methylpicolinonitrile ISO 9001：2015 REACH

3-Methylpyridin-2-carbonitrile

2-cyno,3-Methyl pyridine

20970-75-6

20970-45-6

C7 and C8

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Pyridines, Pyrimidines, Purines and Pteredines

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