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IMidazo[1,2-a]pyridine-3-aceticacid,ethylester

Product Name
IMidazo[1,2-a]pyridine-3-aceticacid,ethylester
CAS No.
101820-69-3
Chemical Name
IMidazo[1,2-a]pyridine-3-aceticacid,ethylester
Synonyms
Minodronic Impurity 7;Minodronic Acid Impurity;Minodronic Acid interMediate;Minodronic acid InterMediate A;Ethyl imidazo[1,2-a]pyridine-3-acetate;ETHYL IMIDAZO[1,2-A]PYRIDIN-3-YL-ACETATE;ethyl 2-(iMidazo[1,2-a]pyridin-3-yl)acetate;Imidazolio [1, 2-A] pyridine-3-ethyl acetate;Midazo[1,2-a]pyridine-3-aceticacid,ethylester;IMidazo[1,2-a]pyridine-3-aceticacid,ethylester
CBNumber
CB62594901
Molecular Formula
C11H12N2O2
Formula Weight
204.23
MOL File
101820-69-3.mol
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IMidazo[1,2-a]pyridine-3-aceticacid,ethylester Property

Density 
1.19±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
6.27±0.50(Predicted)
Appearance
Light yellow to light brown Solid
InChI
InChI=1S/C11H12N2O2/c1-2-15-11(14)7-9-8-12-10-5-3-4-6-13(9)10/h3-6,8H,2,7H2,1H3
InChIKey
SFCNXCZZKZRJLZ-UHFFFAOYSA-N
SMILES
C12=NC=C(CC(OCC)=O)N1C=CC=C2
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Matrix Scientific
Product number
123778
Product name
Ethylimidazo[1,2-a]pyridine-3-acetate
Purity
95+%
Packaging
1g
Price
$446
Updated
2021/12/16
Chemenu
Product number
CM151465
Product name
Ethylimidazo[1,2-a]pyridine-3-acetate
Purity
95+%
Packaging
100mg
Price
$55
Updated
2021/12/16
Chemenu
Product number
CM151465
Product name
Ethylimidazo[1,2-a]pyridine-3-acetate
Purity
95+%
Packaging
250mg
Price
$83
Updated
2021/12/16
Ambeed
Product number
A199799
Product name
Ethyl2-(imidazo[1,2-a]pyridin-3-yl)acetate
Purity
97%
Packaging
1g
Price
$141
Updated
2021/12/16
Chemenu
Product number
CM151465
Product name
Ethylimidazo[1,2-a]pyridine-3-acetate
Purity
95+%
Packaging
1g
Price
$162
Updated
2021/12/16
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IMidazo[1,2-a]pyridine-3-aceticacid,ethylester Chemical Properties,Usage,Production

Synthesis

504-29-0

13176-46-0

101820-69-3

(1) To a 100 mL three-neck flask was added 10.83 g (51.8 mmol) of ethyl 4-bromo-3-oxobutanoate and 0.97 g of reaction promoter M (consisting of zinc nitrate and glycine in a weight ratio of 7:1, pre-dissolved in a solvent mixture of 10 mL of water and 20 mL of 1,4-dioxane). The reaction mixture was stirred at room temperature for 15 min, followed by the addition of 5.36 g (57 mmol) of 2-aminopyridine. The reaction system was warmed up to 70 °C with continuous stirring for 3.5 hours. The progress of the reaction was monitored by TLC until complete conversion of ethyl 4-bromo-3-oxobutanoate. After completion of the reaction, the mixture was filtered and the filtrate was concentrated under reduced pressure. It was extracted three times with 50 mL of water and washed three times with 50 mL of saturated brine. The organic phases were combined, the solvents were removed under reduced pressure and dried to give 10.17 g of a light yellow oily product, ethyl 2-(imidazo[1,2-a]pyridin-3-yl)acetate, in 94.1% yield and 97.9% purity.

References

[1] Patent: CN105175446, 2017, B. Location in patent: Paragraph 0038; 0039; 0040; 0045; 0050; 0055; 0064; 0066

IMidazo[1,2-a]pyridine-3-aceticacid,ethylester Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from IMidazo[1,2-a]pyridine-3-aceticacid,ethylester manufacturers

Henan Fengda Chemical Co., Ltd
Product
Ethyl imidazo[1,2-a]pyridin-3-ylacetate 101820-69-3
Price
US $30.00-0.90/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-26
Career Henan Chemical Co
Product
IMidazo[1,2-a]pyridine-3-aceticacid,ethylester 101820-69-3
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000KG
Release date
2018-08-16

101820-69-3, IMidazo[1,2-a]pyridine-3-aceticacid,ethylesterRelated Search:


  • IMidazo[1,2-a]pyridine-3-aceticacid,ethylester
  • ETHYL IMIDAZO[1,2-A]PYRIDIN-3-YL-ACETATE
  • Minodronic Acid interMediate
  • ethyl 2-(iMidazo[1,2-a]pyridin-3-yl)acetate
  • Minodronic acid InterMediate A
  • 2-(iMidazo[1,2-a]pyridin-3-yl)acetic acid ethyl ester
  • Midazo[1,2-a]pyridine-3-aceticacid,ethylester
  • Ethyl imidazo[1,2-a]pyridine-3-acetate
  • Minodronic Acid Impurity
  • Imidazolio [1, 2-A] pyridine-3-ethyl acetate
  • Minodronic Impurity 7
  • 101820-69-3