ChemicalBook > CAS DataBase List > O-TOLUIDINE HYDROCHLORIDE

O-TOLUIDINE HYDROCHLORIDE

Product Name
O-TOLUIDINE HYDROCHLORIDE
CAS No.
636-21-5
Chemical Name
O-TOLUIDINE HYDROCHLORIDE
Synonyms
nci-c02335;o-ToluidineHCL;o-Tolidine hydroch;ORTHO-TOLUIDINEHCL;rcrawastenumberu222;o-Toluidine Chloride;Prilocaine impurity B;PRILOCAINE RC A/ORTHO;O-TOLUIDINIUM CHLORIDE;o-toluidinhydrochloride
CBNumber
CB6264228
Molecular Formula
C7H10ClN
Formula Weight
143.61
MOL File
636-21-5.mol
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O-TOLUIDINE HYDROCHLORIDE Property

Melting point:
215-217 °C(lit.)
Boiling point:
242 °C
Density 
1.0968 (rough estimate)
refractive index 
1.5760 (estimate)
storage temp. 
2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly), Water (Slightly)
color 
White to Grey
BRN 
3558629
Stability:
Stable. Incompatible with oxidizing agents, alkalies. Light and moisture sensitive.
InChIKey
OGVXWEOZQMAAIM-UHFFFAOYSA-N
CAS DataBase Reference
636-21-5(CAS DataBase Reference)
EPA Substance Registry System
o-Toluidine hydrochloride (636-21-5)
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Safety

Hazard Codes 
T
Risk Statements 
45-20/21/22
Safety Statements 
53-36/37/39-45
RIDADR 
UN 2811 6.1/PG 2
WGK Germany 
3
RTECS 
XU7350000
HazardClass 
6.1(a)
PackingGroup 
II
HS Code 
2921430000
Hazardous Substances Data
636-21-5(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H350May cause cancer

Precautionary statements

P201Obtain special instructions before use.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR3107
Product name
Prilocaine Related Compound A
Purity
pharmaceutical secondary standard, certified reference material
Packaging
200MG
Price
$485
Updated
2024/03/01
Sigma-Aldrich
Product number
1561019
Product name
Prilocaine Related Compound A
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
100mg
Price
$1310
Updated
2024/03/01
Usbiological
Product number
461372
Product name
o-Toluidine Chloride
Packaging
50mg
Price
$305
Updated
2021/12/16
TRC
Product number
T536215
Product name
o-ToluidineChloride
Packaging
1g
Price
$65
Updated
2021/12/16
TRC
Product number
T536215
Product name
o-ToluidineChloride
Packaging
25g
Price
$125
Updated
2021/12/16
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O-TOLUIDINE HYDROCHLORIDE Chemical Properties,Usage,Production

Chemical Properties

white crystalline powder

Uses

o-Toluidine and o-toluidine hydrochloride are used primarily as intermediates in the manufacture of more than 90 dyes and pigments (NCI 1979, IARC 1982, 2000). They are used in acid-fast dyestuffs, azo pigments and dyes, triarylmethane dyes, sulfur dyes, and indigo compounds and as a photographic dye. o-Toluidine is also used as an intermediate for synthetic rubber and rubber vulcanizing chemicals, pharmaceuticals, and pesticides and as a curing agent in epoxy resin systems. Other minor uses of o-toluidine and its hydrochloride salt are as an intermediate in organic synthesis and as an ingredient in a clinical laboratory reagent for glucose and hemoglobin analyses.

Uses

o-Toluidine Chloride is a carcinogenic and toxic aromatic amine contained in hair dye, henna and dyed hair samples. Prilocaine USP Related Compound A

General Description

Green crystals or white crystalline solid. Melting point 215-217°F. Highly toxic.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

O-TOLUIDINE HYDROCHLORIDE acts as a weak acid. Incompatible with oxidizing agents and with alkalis .

Fire Hazard

Flash point data for O-TOLUIDINE HYDROCHLORIDE are not available; however, O-TOLUIDINE HYDROCHLORIDE is probably combustible.

Safety Profile

Confirmed carcinogen with experimental carcinogenic data. Poison by intraperitoneal route. Moderately toxic by ingestion. Mutation data reported. When heated to decomposition it emits very toxic fumes of HCl and NOx. See also o- TOLUIDINE.

Carcinogenicity

o-Toluidine and o-toluidine hydrochloride are reasonably anticipatedto be human carcinogens based on sufficient evidence of carcinogenicity from studies in experimental animals.

O-TOLUIDINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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O-TOLUIDINE HYDROCHLORIDE Suppliers

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View Lastest Price from O-TOLUIDINE HYDROCHLORIDE manufacturers

Career Henan Chemical Co
Product
O-TOLUIDINE HYDROCHLORIDE 636-21-5
Price
US $9.80/KG
Min. Order
1g
Purity
≥99%
Supply Ability
100kg
Release date
2020-01-08

636-21-5, O-TOLUIDINE HYDROCHLORIDERelated Search:


  • o-Tolidine hydroch
  • o-ToluidineHCL
  • ORTHO-TOLUIDINEHCL
  • ORTHO-TOLUIDINEHYDROCHLORIDE
  • Prilocaine Related Compound A (100 mg) (o-toluidine hydrochloride)
  • Prilocaine Related CoMpound A
  • Prilocaine EP Impurity B
  • Prilocaine impurity B
  • O-AMINOTOLUENE HYDROCHLORIDE
  • O-TOLUIDINE HYDROCHLORIDE
  • O-TOLUIDINIUM CHLORIDE
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  • 1-methyl-2-aminobenzenehydrochloride
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  • 2-methylbenzenaminehydrochloride
  • 2-methyl-benzenaminhydrochloride
  • 2-toluidine,hydrochloride
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  • Benzenamine,2-methyl-,hydrochloride
  • nci-c02335
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  • o-methylbenzenaminehydrochloride
  • ortho-aminotoluenehydrochloride
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  • o-tolylaminehydrochloride
  • rcrawastenumberu222
  • toluene,2-amino,hydrochloride
  • 2-AMINOTOLUENE HYDROCHLORIDE
  • 2-AMINO-1-METHYLBENZENE HYDROCHLORIDE
  • 2-METHYLANILINE HYDROCHLORIDE
  • o-Toluidine Chloride
  • Prilocaine Impurity 2(Prilocaine EP Impurity B)
  • o-ToluidineHydrochloride&gt
  • 1-methylaniline hydrochloride
  • O-TOLUIDINE HYDROCHLORIDE ISO 9001:2015 REACH
  • Prilocaine Related Compound A (o-toluidine hydrochloride) (1561019)
  • Prilocaine EP Impurity B HCl
  • Prilocaine Related Compound A as Hydrochloride
  • Prilocaine USP Related Compound A as Hydrochloride
  • Prilocaine Related Compound A HCl
  • Prilocaine Hydrochloride EP Impurity B as Hydrochloride
  • Prilocaine Impurity 2(Prilocaine EP Impurity B HCl)
  • Prilocaine Hydrochloride Impurity B as Hydrochloride
  • PRILOCAINE RC A/ORTHO
  • Prilocaine Impurity 10 HCl
  • Prilocaine Related Compound A(Hydrochloride)
  • Linagliptin Impurity CD10142
  • 2-Methylbenzenamine Hydrochloride (o-Toluidine Hydrochloride)
  • 636-21-5
  • Organic Building Blocks
  • Nitrogen Compounds
  • Building Blocks
  • Amine Salts
  • amine