ECDYSONE-2-ACETATE, BETA-(SH)

Product Name: ECDYSONE-2-ACETATE, BETA-(SH)
CAS No.: 19536-25-5
Chemical Name: ECDYSONE-2-ACETATE, BETA-(SH)
Synonyms: β-Ecdysone 2-acetate;ECDYSONE-2-ACETATE, BETA-;20-Hydroxyecdysone 2-acetate;20-hydroxyeedysone 2-acetate;ECDYSONE-2-ACETATE, BETA-(SH);2-O-Acetyl-20-hydroxyecdysone;(2β,3β,5β,22R)-2-(Acetyloxy)-3,14,20,22,25-pentahydroxycholest-7-en-6-one;Cholest-7-en-6-one, 2-(acetyloxy)-3,14,20,22,25-pentahydroxy-, (2β,3β,5β,22R)-;(2S,3R,5R,9R,10R,13R,17S)-3,14-Dihydroxy-10,13-dimethyl-6-oxo-17-((2R,3R)-2,3,6-trihydroxy-6-methylheptan-2-yl)-2,3,4,5,6,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-2-yl acetate
CBNumber: CB62650586
Molecular Formula: C29H46O8
Formula Weight: 522.68
MOL File: 19536-25-5.mol

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ECDYSONE-2-ACETATE, BETA-(SH) Property

Melting point:: 218-220 °C
Boiling point:: 707.3±60.0 °C(Predicted)
Density: 1.26±0.1 g/cm3(Predicted)
solubility: DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 20 mg/ml; PBS (pH 7.2): 10 mg/ml
form: A solid
pka: 13.96±0.70(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 28063
Product name: 2-O-Acetyl-20-hydroxyecdysone
Packaging: 1mg
Price: $57
Updated: 2024/03/01

Cayman Chemical

Product number: 28063
Product name: 2-O-Acetyl-20-hydroxyecdysone
Packaging: 10mg
Price: $437
Updated: 2024/03/01

Cayman Chemical

Product number: 28063
Product name: 2-O-Acetyl-20-hydroxyecdysone
Packaging: 5mg
Price: $249
Updated: 2024/03/01

Biosynth Carbosynth

Product number: FA168797
Product name: 2-O-Acetyl-20-Hydroxyecdysone
Packaging: 1mg
Price: $125
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA168797
Product name: 2-O-Acetyl-20-Hydroxyecdysone
Packaging: 2mg
Price: $200
Updated: 2021/12/16

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ECDYSONE-2-ACETATE, BETA-(SH) Chemical Properties,Usage,Production

Description

2-O-Acetyl-20-hydroxyecdysone is an ecdysone steroid hormone that has been found in plants and animals. It completely inhibits the growth of the bacteria S. aureus, E. coli, and P. vulgaris, as well as the fungi C. albicans, A. alternata, and F. solani when used at a concentration of 10 μg/ml. 2-O-Acetyl-20-hydroxyecdysone (50 μM) increases aggregation of amyloid-β (1-42) (Aβ42), increases fibril formation by 60%, and decreases oligomer levels in cell-free assays. It reduces Aβ42-induced cytotoxicity of SH-SY5Y cells when used at concentrations of 5 and 10 μM.

Uses

2-O-Acetyl-20-hydroxyecdysone, an ecdysterones in insects and terrestrial plants, inhibits amyloid-β42 (Aβ42)-induced cytotoxicity. 2-O-Acetyl-20-hydroxyecdysone could decrease Aβ oligomer formation through promotion of fibrogenesis, transforming Aβ oligomers to the low-toxicity fibrils[1].

References

[1] Yang SG, et al. Diverse ecdysterones show different effects on amyloid-β42 aggregation but all uniformly inhibit amyloid-β42-induced cytotoxicity. J Alzheimers Dis. 2010;22(1):107-17. DOI:10.3233/JAD-2010-100621

ECDYSONE-2-ACETATE, BETA-(SH) Preparation Products And Raw materials

Raw materials

Preparation Products

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ECDYSONE-2-ACETATE, BETA-(SH) Suppliers

China 46 India 1 United Kingdom 1 United States 5 Global 53

ShangHai YuanYe Biotechnology Co., Ltd.

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19536-25-5, ECDYSONE-2-ACETATE, BETA-(SH)Related Search:

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ECDYSONE-2-ACETATE, BETA-(SH)

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β-Ecdysone 2-acetate

ECDYSONE-2-ACETATE, BETA-

(2S,3R,5R,9R,10R,13R,17S)-3,14-Dihydroxy-10,13-dimethyl-6-oxo-17-((2R,3R)-2,3,6-trihydroxy-6-methylheptan-2-yl)-2,3,4,5,6,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-2-yl acetate

19536-25-5