ChemicalBook > CAS DataBase List > ((R)-3-Methyl-1-((R)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid

((R)-3-Methyl-1-((R)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid

Product Name
((R)-3-Methyl-1-((R)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid
CAS No.
1132709-15-9
Chemical Name
((R)-3-Methyl-1-((R)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid
Synonyms
(1R,2R)-BortezoMib;Bortezomib USP RC A;(1R,2R)-Bortezomib Impurity;Bortizomib RR (Diastereomer);Bortezomib Diastereomer (R,R);Boron tezomio enantiomers (RR);Bortezomib USP Related Compoud H;Bortezomib impurity 1/(1R,2R)-Bortezomib;((R)-3-Methyl-1-((R)-3-phenyl-2-(pyrazine-2-carboxaMido)prop;N-(2-Pyrazinecarbonyl)-D-phenylalanine-L-leucine boronic anhydride
CBNumber
CB62661607
Molecular Formula
C19H25BN4O4
Formula Weight
384.24
MOL File
1132709-15-9.mol
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((R)-3-Methyl-1-((R)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid Property

Density 
1.214±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
Chloroform (Slightly), DMSO (Slightly, Heated), Methanol (Slightly)
form 
Solid
pka
9.66±0.43(Predicted)
color 
White to Off-White
InChIKey
GXJABQQUPOEUTA-WBVHZDCISA-N
SMILES
B([C@@H](NC(=O)[C@H](NC(C1=NC=CN=C1)=O)CC1=CC=CC=C1)CC(C)C)(O)O
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B675705
Product name
(1R,2R)-Bortezomib
Packaging
50mg
Price
$1355
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
54773
Product name
(1R,2R)-Bortezomib
Packaging
5mg
Price
$490
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
BOR0007356
Product name
((R)-3-METHYL-1-((R)-3-PHENYL-2-(PYRAZINE-2-CARBOXAMIDO)PROPANAMIDO)BUTYL)BORONIC ACID
Purity
95.00%
Packaging
5MG
Price
$495.73
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
BOR0007356
Product name
((R)-3-METHYL-1-((R)-3-PHENYL-2-(PYRAZINE-2-CARBOXAMIDO)PROPANAMIDO)BUTYL)BORONIC ACID
Purity
95.00%
Packaging
1G
Price
$3975.3
Updated
2021/12/16
Crysdot
Product number
CD11348857
Product name
((R)-3-Methyl-1-((R)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronicacid
Purity
95+%
Packaging
1g
Price
$2450
Updated
2021/12/16
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((R)-3-Methyl-1-((R)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid Chemical Properties,Usage,Production

Uses

(1R,2R)-Bortezomib is a diastereomer of Bortezomib (B675700), the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway

((R)-3-Methyl-1-((R)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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((R)-3-Methyl-1-((R)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid Suppliers

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View Lastest Price from ((R)-3-Methyl-1-((R)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid manufacturers

Moxin Chemicals
Product
Bortezomib Impurity 1132709-15-9
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
95%+
Supply Ability
100000
Release date
2025-01-16
Career Henan Chemical Co
Product
((R)-3-Methyl-1-((R)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid 1132709-15-9
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
10000KGS
Release date
2020-01-14

1132709-15-9, ((R)-3-Methyl-1-((R)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acidRelated Search:

2-PyrazinecarboxaMide, N,N',N''-[2,4,6-boroxintriyltris[[(1R)-3-Methylbutylidene]iMino[(1S)-2-oxo-1-(phenylMethyl)-2,1-ethanediyl]]]tris- BORTEZOMIB-PINANEDIOL Bortezomib Impurity 2 (Mixture of (1S,2R)-Isomer and (1R,2R)-Isomer) Bortezomib Impurity 1 (R,S-Isomer) BortezoMib IMpurity 2 (RR-IsoMer) 2-PyrazinecarboxaMide, N-[(1S)-2-[[(1R)-1-hydroperoxy-3-Methylbutyl]aMino]-2-oxo-1-(phenylMethyl)ethyl]- (S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide 2-PyrazinecarboxaMide, N-[(1S)-2-[[(1S)-1-hydroperoxy-3-Methylbutyl]aMino]-2-oxo-1-(phenylMethyl)ethyl]- N-((S)-1-(((R)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide Bortezomib (S)-3-PHENYL-2-[(PYRAZIN-2-YLCARBONYL)AMINO] PROPANOIC ACID (aR,3aS,4S,6S,7aR)-Hexahydro-3a,8,8-trimethyl-alpha-(2-methylpropyl)-4,6-methano-1,3,2-benzodioxaborole-2-methanamine 2,2,2-trifluoroacetate ((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]-

  • ((R)-3-Methyl-1-((R)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid
  • (1R,2R)-BortezoMib
  • N-(2-Pyrazinecarbonyl)-D-phenylalanine-L-leucine boronic anhydride
  • Bortezomib impurity 1/(1R,2R)-Bortezomib
  • [(1R)-3-methyl-1-[[(2R)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoyl]amino]butyl]boronic acid
  • [(1R)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic acid
  • (1R,2R)-Bortezomib Impurity
  • [(1R)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic Acid
  • B-[(1R)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic Acid
  • Bortezomib USP Related Compoud H
  • Bortezomib USP RC A
  • Boronic acid, B-[(1R)-3-methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]-
  • Boron tezomio enantiomers (RR)
  • Bortizomib RR (Diastereomer)
  • Bortezomib Related Compound A/ Bortezomib Impurity D (Bortezomib R,R-Isomer Impurity)
  • Bortezomib 1R, 2R IsomerQ: What is Bortezomib 1R, 2R Isomer Q: What is the CAS Number of Bortezomib 1R, 2R Isomer Q: What is the storage condition of Bortezomib 1R, 2R Isomer Q: What are the applications of Bortezomib 1R, 2R Isomer
  • Bortezomib Diastereomer (R,R)
  • ((R)-3-Methyl-1-((R)-3-phenyl-2-(pyrazine-2-carboxaMido)prop
  • 1132709-15-9
  • Chiral Reagents, Boron Derivatives, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals