BenzenesulfonaMide, N-[1,6-dihydro-5-(2-Methoxyphenoxy)-6-oxo[2,2'-bipyriMidin]-4-yl]-4-(1,1-diMethylethyl)-

Product Name: BenzenesulfonaMide, N-[1,6-dihydro-5-(2-Methoxyphenoxy)-6-oxo[2,2'-bipyriMidin]-4-yl]-4-(1,1-diMethylethyl)-
CAS No.: 174227-14-6
Chemical Name: BenzenesulfonaMide, N-[1,6-dihydro-5-(2-Methoxyphenoxy)-6-oxo[2,2'-bipyriMidin]-4-yl]-4-(1,1-diMethylethyl)-
Synonyms: Bosentan USP RC B;Bosentan IMpurity D;Bosentan EP Impurity-B;O-Deshydroxyethyl Bosentan;Bosentan Related CoMpound B;Bosentan USP Related Compound B;Bosentan Related Compound B (O-Deshydroxyethyl Bosentan);4-(tert-butyl)-N-(6-hydroxy-5-(2-methoxyphenoxy)-[2,2-bipyrimidin]-4-yl)benzenesulfonamide;p-tert-butyl-N-[6-(hydroxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]benzene sulfonamide;4-(tert-butyl)-N-(6-hydroxy-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide
CBNumber: CB62667876
Molecular Formula: C25H25N5O5S
Formula Weight: 507.56
MOL File: 174227-14-6.mol

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BenzenesulfonaMide, N-[1,6-dihydro-5-(2-Methoxyphenoxy)-6-oxo[2,2'-bipyriMidin]-4-yl]-4-(1,1-diMethylethyl)- Property

Melting point:: >218°C (dec.)
Boiling point:: 690.0±65.0 °C(Predicted)
Density: 1.34±0.1 g/cm3(Predicted)
storage temp.: Refrigerator
solubility: DMSO (Slightly), Chloroform (Slightly), Methanol (Slightly)
form: Solid
pka: 4.48±0.50(Predicted)
color: Pale Beige to Light Beige

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Safety

HS Code: 2935909550

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 1076137
Product name: Bosentan Related Compound B
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 15mg
Price: $1300
Updated: 2025/07/31

TRC

Product number: D290485
Product name: O-DeshydroxyethylBosentan
Packaging: 500mg
Price: $1390
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD64077
Product name: O-Deshydroxyethyl bosentan
Packaging: 1mg
Price: $120
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD64077
Product name: O-Deshydroxyethyl bosentan
Packaging: 2mg
Price: $200
Updated: 2021/12/16

ChemScene

Product number: CS-M2104
Product name: Benzenesulfonamide,N-[1,6-dihydro-5-(2-methoxyphenoxy)-6-oxo[2,2'-bipyrimidin]-4-yl]-4-(1,1-dimethylethyl)-
Packaging: 1g
Price: $350
Updated: 2021/12/16

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BenzenesulfonaMide, N-[1,6-dihydro-5-(2-Methoxyphenoxy)-6-oxo[2,2'-bipyriMidin]-4-yl]-4-(1,1-diMethylethyl)- Chemical Properties,Usage,Production

Uses

O-Deshydroxyethyl Bosentan (Bosentan USP Related Compound B) is an impurity of Bosentan (B675900); a mixed endothelin receptor antagonist. Used as a vasodilator and antihypertensive.

BenzenesulfonaMide, N-[1,6-dihydro-5-(2-Methoxyphenoxy)-6-oxo[2,2'-bipyriMidin]-4-yl]-4-(1,1-diMethylethyl)- Preparation Products And Raw materials

Raw materials

Preparation Products

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BenzenesulfonaMide, N-[1,6-dihydro-5-(2-Methoxyphenoxy)-6-oxo[2,2'-bipyriMidin]-4-yl]-4-(1,1-diMethylethyl)- Suppliers

China 40 India 5 United Kingdom 1 United States 4 Global 50

Daicel Chiral Technologies (China)CO.,LTD

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Fax: +86-21-50462321
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Country: China
ProdList: 7471
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Sinopharm Chemical Reagent Co,Ltd.

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Fax: 86-21-63290778 86-21-63218885
Email: sj_scrc@sinopharm.com
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Nanjing XiZe Biotechnology CO., Ltd.

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Tonichem Pharmaceutical Technology Co., Ltd.

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174227-14-6, BenzenesulfonaMide, N-[1,6-dihydro-5-(2-Methoxyphenoxy)-6-oxo[2,2'-bipyriMidin]-4-yl]-4-(1,1-diMethylethyl)-Related Search:

Bosentan Related Compound 4 4-tert-Butyl-N-(6-chloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl)benzenesulfonamide 4-tert-Butylbenzenesulfonamide Bosentan Impurity 15 HCl 4,6-Dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine Bosentan Related Compound 5 Bosentan hydrate BenzenesulfonaMide, N,N'-[1,2-ethanediylbis[oxy[5-(2-Methoxyphenoxy)[2,2'-bipyriMidine]-6,4-diyl]]]bis[4-(1,1-diMethylethyl)- HYDROXY DESMETHYL BOSENTAN DESMETHYL BOSENTAN Hydroxy Bosentan

BenzenesulfonaMide, N-[1,6-dihydro-5-(2-Methoxyphenoxy)-6-oxo[2,2'-bipyriMidin]-4-yl]-4-(1,1-diMethylethyl)-

Bosentan USP Related Compound B

p-tert-butyl-N-[6-(hydroxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]benzene sulfonamide

Bosentan USP RC B

Bosentan IMpurity D

Bosentan Related CoMpound B

N-[1,6-Dihydro-5-(2-methoxyphenoxy)-6-oxo[2,2'-bipyrimidin]-4-yl]-4-(1,1-dimethylethyl)benzenesulfonamide

Bosentan Related Compound B (15 mg) (4-(tert-butyl)-N-[6-hydroxy-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl]benzenesulfonamide)

O-Deshydroxyethyl Bosentan

Bosentan USP Related Compound B: 4-(tert-Butyl)-N-[6-hydroxy-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl]benzenesulfonamide

4-(tert-butyl)-N-(6-hydroxy-5-(2-methoxyphenoxy)-[2,2-bipyrimidin]-4-yl)benzenesulfonamide

Bosentan Related Compound B (O-Deshydroxyethyl Bosentan)

Bosentan Related Compound B (4-(tert-butyl)-N-[6-hydroxy-5-(2-methoxyphenoxy)-(2,2''-bipyrimidin)-4- (1076137)

4-(tert-butyl)-N-(6-hydroxy-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide

Bosentan EP Impurity-B

174227-14-6

C25H25N5O5S