ChemicalBook > CAS DataBase List > 2-Amino-4-chloropyrrolo[2,3-d]pyrimidine

2-Amino-4-chloropyrrolo[2,3-d]pyrimidine

Product Name
2-Amino-4-chloropyrrolo[2,3-d]pyrimidine
CAS No.
84955-31-7
Chemical Name
2-Amino-4-chloropyrrolo[2,3-d]pyrimidine
Synonyms
4-CHLORO-7H-PYRROLO[2,3-D]PYRIMIDIN-2-AMINE;6-CHLORO-7-DEAZAGUANINE;3-d]pyriMidin-2-aMine;2-Amino-4-Chloro-7H-pyrro...;2-amino-6-chloro-7-deazapurine;-Amino-4-chloropyrrolo[2,3-d]pyrimidine;2-Amino-4-chloropyrrolo[2,3-d]pyrimidine;4-Chloro-7H-pyrrolo[2,3-d]pyrimidin-2-ylam;4-chloro-1H-pyrrolo[2,3-d]pyriMidin-2-aMine;2-Amino-4-Chloro-7H-pyrrolo[2,3-d]pyrimidine
CBNumber
CB6270612
Molecular Formula
C6H5ClN4
Formula Weight
168.58
MOL File
84955-31-7.mol
More
Less

2-Amino-4-chloropyrrolo[2,3-d]pyrimidine Property

Melting point:
215-217°C
Boiling point:
346.6±52.0 °C(Predicted)
Density 
1.82±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly, Sonicated)
pka
10.68±0.20(Predicted)
form 
Powder
color 
Pale yellow to yellow
Stability:
Hygroscopic
InChI
InChI=1S/C6H5ClN4/c7-4-3-1-2-9-5(3)11-6(8)10-4/h1-2H,(H3,8,9,10,11)
InChIKey
VIVLSUIQHWGALQ-UHFFFAOYSA-N
SMILES
C1(N)=NC(Cl)=C2C=CNC2=N1
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36
Safety Statements 
26
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
2933998090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More
Less

N-Bromosuccinimide Price

TRC
Product number
C365170
Product name
6-Chloro-7-deazaguanine
Packaging
10g
Price
$85
Updated
2021/12/16
Usbiological
Product number
C4979
Product name
6-Chloro-7-deazaguanine
Packaging
200mg
Price
$403
Updated
2021/12/16
Matrix Scientific
Product number
066665
Product name
4-Chloro-7H-pyrrolo[2,3-d]pyrimidin-2-amine
Packaging
1g
Price
$25
Updated
2021/12/16
Apolloscientific
Product number
OR17061
Product name
2-Amino-4-chloro-7H-pyrrolo[2,3-d]pyrimidine
Purity
95+%
Packaging
1g
Price
$34
Updated
2021/12/16
SynQuest Laboratories
Product number
3H30-5-Y8
Product name
2-Amino-4-chloro-7H-pyrrolo[2,3-d]pyrimidine
Purity
95.0%
Packaging
1g
Price
$37
Updated
2021/12/16
More
Less

2-Amino-4-chloropyrrolo[2,3-d]pyrimidine Chemical Properties,Usage,Production

Chemical Properties

White Crystalline Solid

Uses

6-Chloro-7-deazaguanine (cas# 84955-31-7) is a compound useful in organic synthesis.

Synthesis

7355-55-7

84955-31-7

2-Amino-4-hydroxypyrrolo[2,3-d]pyrimidine (10.0 g, 66.6 mmol) was added to 100 mL of phosphorus oxychloride (POCl3) and the reaction was carried out at reflux for 2 hours. After completion of the reaction, the solvent was removed by rotary evaporator. After the reaction mixture was cooled to room temperature, it was slowly poured into 120 mL of ice water and the solid product was collected by filtration. The filter cake was washed with ice water and the pH of the filtrate was subsequently adjusted to 2 with ammonia solution and cooled in an ice bath for 2 hours to promote precipitation. The solid product was filtered again and washed sequentially with 10 mL of ice water and 30 mL of ether, resulting in 8.7 g of 2-amino-4-chloropyrrolo[2,3-d]pyrimidine in 78% yield.

References

[1] Liebigs Annalen der Chemie, 1987, p. 15 - 19
[2] Angewandte Chemie - International Edition, 2007, vol. 46, # 13, p. 2325 - 2327
[3] Patent: CN103819523, 2016, B. Location in patent: Paragraph 0048; 0049; 0050
[4] Liebigs Annalen der Chemie, 1983, # 1, p. 137 - 146
[5] Bioorganic and Medicinal Chemistry Letters, 2013, vol. 23, # 7, p. 2260 - 2264

2-Amino-4-chloropyrrolo[2,3-d]pyrimidine Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

2-Amino-4-chloropyrrolo[2,3-d]pyrimidine Suppliers

Canada 2 China 183 Germany 3 India 1 United Kingdom 3 United States 24 Global 216
Shanghai Arbor Chemical Co., Ltd.
Tel
021-60451683 15021268886
Fax
+86-21-60451682
Email
sales@arborchemical.com
Country
China
ProdList
896
Advantage
55
Established by Hangzhou Boman Biochem Tech Co., Ltd
Tel
13588048971
Email
sales@bomanbiochem.com
Country
China
ProdList
476
Advantage
58
Shandong Shenganbei New Energy Co. , Ltd. . Nanjing branch
Tel
18761883648
Email
sab202211@163.com
Country
China
ProdList
1665
Advantage
58
Aikon International Limited
Tel
025-58851090 15955137747
Fax
(6)02557626880
Email
sales01@aikonchem.com
Country
China
ProdList
15949
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15838
Advantage
69
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
Advantage
66
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9310
Advantage
66
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11035
Advantage
64
Shanghai Boc Chemical Co.,Ltd
Tel
021-34975603-808 18721111801
Fax
+86-21-34975602-805
Email
sales@bocpharma.com
Country
China
ProdList
1009
Advantage
64
ZEROSCHEM.CO.,LTD.
Tel
10-61256048 13810278579
Fax
+86 10 61256049
Email
sales@zeroschem.com
Country
China
ProdList
1371
Advantage
59
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
16075
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
ChangZhou SIDU chemical Co., Ltd.
Tel
0519-81291281 18015082300
Fax
0519-81291281
Email
siduchem@hotmail.com
Country
China
ProdList
274
Advantage
62
SpringPharma Tech Co.,Ltd
Tel
+86-25-68710855, +86-25-68710897
Fax
025-68710856
Email
sales@springpharma.net
Country
China
ProdList
1261
Advantage
62
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
18270980682
Fax
021 51613951
Email
mlcheng@sunwaypharm.cn
Country
China
ProdList
8669
Advantage
57
QINGDAO CARELONGPHARMATECH CO.,LTD
Tel
0532-0532-88191853 13061484198
Fax
+86-532-88191853
Email
sales@carelongchem.com
Country
China
ProdList
439
Advantage
57
Shanghai Sphchem Co., Ltd.
Tel
021-56491756 13512199871
Fax
021-5649-1756
Email
2819742715@qq.com
Country
China
ProdList
4000
Advantage
55
Okeanos Tech Co,. Ltd.
Tel
010-62651721 18610486005
Fax
01062651521-808
Email
minghui.yu@okeanos.com.cn
Country
China
ProdList
495
Advantage
60
ShangHai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847 13636370518
Fax
021-55068248
Email
shyysw007@163.com
Country
China
ProdList
4999
Advantage
60
Shanghai LiangYi Fine Chemicals Co., Ltd.
Tel
021-62594801
Fax
021-62145414
Email
shliangyi@liangyichem.com
Country
China
ProdList
50
Advantage
58
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9510
Advantage
58
Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
ProdList
9891
Advantage
58
Nanjing Norris-Pharm Technology Co., Ltd
Tel
18652989687
Fax
+86-25-52131256
Email
sales@norris-pharm.com
Country
China
ProdList
8878
Advantage
55
Nanjing Baifuli Technology Co., Ltd.
Tel
25-25-58740604 15951658055
Fax
+86-25-58356858
Email
sales@unisyn.cn
Country
China
ProdList
591
Advantage
58
Bsisun HK Imoprt And Export Company Limited
Tel
+86-18068513926
Fax
0086-519-85153711
Country
China
ProdList
1277
Advantage
55
Chem-Stone Co.,Ltd.
Tel
020-82185713,82185709 13418171485
Fax
020-82185696
Email
sales@chem-stone.com
Country
China
ProdList
744
Advantage
56
CEG Chemical Science&Technology Co., Ltd.
Tel
Mobile:13665161512
Fax
+86-510-68873513
Country
China
ProdList
1785
Advantage
58
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
ShangHai D&B Biological Science and Technology Co.Ltd
Tel
400-008-9730,021-54359730 400-008-9730
Fax
021-54353864
Email
info@chemxyz.com
Country
China
ProdList
3057
Advantage
60
Shanghai YuYuan Pharmaceutical Co., Ltd.
Tel
13052276172
Fax
13052276172
Email
product@yuyuanpharm.com
Country
China
ProdList
493
Advantage
55
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15178
Advantage
58
Jiaxing Novartis Chemical Co., Ltd.
Tel
18957373295
Fax
-
Country
China
ProdList
1580
Advantage
58
Suzhou yacoo science co.,Ltd
Tel
0512-87182056 18013166090
Fax
0512-87182056
Email
lingling.qi@yacoo.com.cn
Country
China
ProdList
6295
Advantage
60
Shanghai Xingui Biotechnology Co., Ltd.
Tel
15121041756
Email
xingui2022@126.com
Country
China
ProdList
9979
Advantage
58
Hangzhou J&H Chemical Co., Ltd.
Tel
0571-87396432
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
14912
Advantage
59
Shanghai Song Yuan Chemical Technology Co., Ltd.
Tel
010-1234567 18521000990
Fax
86-021-33275113
Email
sonyuanchemical@163.com
Country
China
ProdList
6479
Advantage
50
Shanghai ZhengXia Medical Technology Co., Ltd.
Tel
13585673075
Email
317388297@qq.com
Country
China
ProdList
254
Advantage
50
Shanghai LanRun Chemical Co., Ltd.
Tel
021-69515658 ; 69515628 13701998368
Fax
021-69515998
Email
longrunchem@163.com
Country
China
ProdList
3786
Advantage
50
Hotechem Shanghai Co., Ltd.,
Tel
021-34621078 13120882795
Fax
021-34622517
Email
465106944@qq.com
Country
China
ProdList
857
Advantage
56
Jiangsu Mingchem Corporation
Tel
0519-85170101
Fax
0519-85170505
Email
sales@mingchem.com
Country
China
ProdList
608
Advantage
55
Ningbo Materials-X Co., Ltd
Tel
0574-87487840-805 15888368997
Fax
0574-87485342
Country
China
ProdList
474
Advantage
55
Nanjing Chempioneer Pharmaceutical Co., Ltd.
Tel
18068075658
Fax
-
Email
sales@chempioneer.com
Country
China
ProdList
1811
Advantage
58
Struchem Co., Ltd.
Tel
0512-63009836 18994340901
Fax
0512-63006936
Email
helen@struchem.com
Country
China
ProdList
3981
Advantage
60
SPIRO PHARMA
Tel
Fax
-
Email
eric_feng1954@126.com
Country
China
ProdList
9248
Advantage
55
Wuhu Nuowei Chemical Technology Co., Ltd
Tel
0553-0553-8233716-803-803 18055326116
Email
sales@nuowei-chem.com
Country
China
ProdList
953
Advantage
55
Chengdu RunZeBenTu Chemical Co., Ltd
Tel
028-88469284 18000562381
Email
rzbtsj@163.com
Country
China
ProdList
9951
Advantage
56
Chengdu DingDang Pharmaceutical Co., Ltd.
Tel
028-86040038 13980902949;
Fax
028-85149890
Email
market@dingdangchem.com
Country
China
ProdList
1853
Advantage
55
Nanjing Vital Chemical Co., Ltd.
Tel
025-87193546 18652950785
Fax
025-87193546
Email
chemweiao@163.com
Country
China
ProdList
9021
Advantage
60
More
Less

View Lastest Price from 2-Amino-4-chloropyrrolo[2,3-d]pyrimidine manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
2-Amino-4-chloropyrrolo[2,3-d]pyrimidine 84955-31-7
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-28
Zhuozhou Wenxi import and Export Co., Ltd
Product
2-Amino-4-chloropyrrolo[2,3-d]pyrimidine 84955-31-7
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
2-Amino-4-chloropyrrolo[2,3-d]pyrimidine 84955-31-7
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09

84955-31-7, 2-Amino-4-chloropyrrolo[2,3-d]pyrimidineRelated Search:

6-Chloropurine 6-Chloroguanine 2-Amino-4-chloropyrimidine Pyrrolidine 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine Pyrimidine N-Methyl-2-pyrrolidone Guanine 6-Chloropurine ribonucleoside Polyvinylpyrrolidone ALTRENOGEST 2-Aminopyrimidine 8-AZAGUANINE Glycine Difluorochloromethane Propanamide, N-(4-chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-2-yl)-2,2-dimethyl- 2-Aminobenzylchloride Chlordiazepoxide

  • 4-CHLORO-7H-PYRROLO[2,3-D]PYRIMIDIN-2-AMINE
  • 6-CHLORO-7-DEAZAGUANINE
  • 2-Amino-4-chloropyrrolo[2,3-d]pyrimidine
  • 7H-Pyrrolo[2,3-d]pyrimidin-2-amine, 4-chloro-
  • 4-CHLORO-3,7-DIHYDRO-4H-PYRROLO[2,3-D]PYRIMIDIN-2-YLAMINE
  • 4-Chloro-7H-pyrrolo[2,3-d]pyrimidin-2-ylamine
  • 2-Amino-4-Chloro-7H-pyrrolo[2,3-d]pyrimidine
  • 2-amino-6-chloro-7-deazapurine
  • 2-Amino-4-Chloro-7H-pyrro...
  • 3-d]pyriMidin-2-aMine
  • 2-Amino-4-chloropyrrolo[2,3-d]pyrimidine 6-Chloro-7-deazaguanine
  • 4-chloro-1H-pyrrolo[2,3-d]pyriMidin-2-aMine
  • 4-Chloro-7H-pyrrolo[2,3-d]pyrimidin-2-amine, 2-Amino-6-chloro-7-deazapurine
  • 4-Chloro-7H-pyrrolo[2,3-d]pyrimidin-2-ylam
  • 2-Amino-4-chloro-7H-pyrrolo[2,3-d]pyrimidine,97%
  • 2-Amino-4-chloropyrrolo[2,3-d]pyrimidine USP/EP/BP
  • -Amino-4-chloropyrrolo[2,3-d]pyrimidine
  • 2-Amino-4-chloropyrrolo[2,3-d]pyrimidine?New
  • 84955-31-7
  • CHIRAL CHEMICALS
  • Bases & Related Reagents
  • Intermediates
  • Nucleotides