Neohesperidin

Product Name: Neohesperidin
CAS No.: 13241-33-3
Chemical Name: Neohesperidin
Synonyms: NSC 31048;Neohesperdin;NEOHESPERIDIN;Businessperson;Neohesperidin-RM;NEOHESPERIDIN (PR);(2S)-Neohesperidin;Citrus Polyphenols;Neohesperidin, 90%+;Hesperidin Impurity 9
CBNumber: CB6291569
Molecular Formula: C28H34O15
Formula Weight: 610.56
MOL File: 13241-33-3.mol

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Neohesperidin Property

Melting point:: 239-243°C
Boiling point:: 933.7±65.0 °C(Predicted)
Density: 1.65±0.1 g/cm3(Predicted)
vapor pressure: 0Pa at 20℃
storage temp.: Sealed in dry,2-8°C
solubility: DMSO (Slightly), Pyridine (Slightly)
pka: 7.14±0.40(Predicted)
form: Solid
color: White to Off-White
Water Solubility: 3.98mg/L at 20℃
BRN: 74945
InChIKey: ARGKVCXINMKCAZ-RTFRIYMLSA-N
LogP: -0.69 at 20℃
CAS DataBase Reference: 13241-33-3(CAS DataBase Reference)

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Safety

Safety Statements: 22-24/25
WGK Germany: 3
RTECS: DJ2981400
F: 10-21
HS Code: 29389090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHR3213
Product name: Neohesperidin
Purity: pharmaceutical secondary standard, certified reference material
Packaging: 50MG
Price: $461
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1458042
Product name: Neohesperidin
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 30mg
Price: $371.6
Updated: 2024/03/01

Sigma-Aldrich

Product number: 40927
Product name: Neohesperidin
Purity: analytical standard
Packaging: 10mg
Price: $322
Updated: 2021/12/16

TCI Chemical

Product number: N1121
Product name: Neohesperidin
Purity: >97.0%(HPLC)
Packaging: 100mg
Price: $108
Updated: 2024/03/01

Cayman Chemical

Product number: 23028
Product name: Neohesperidin
Purity: ≥98%
Packaging: 100mg
Price: $73
Updated: 2024/03/01

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Neohesperidin Chemical Properties,Usage,Production

Description

Neohesperidin is a flavonoid found in citrus fruit peel that has diverse biological activities. In vitro, it inhibits osteoclast differentiation, bone resorption, calcium oscillations, and activation of NF-κB and nuclear factor of activated T cells (NFAT) by receptor activator of NF-κB ligand (RANKL). In vivo, neohesperidin administration protects ovariectomized mice from bone loss. Neohesperidin acts as a hypolipidemic agent, reducing lipid accumulation in HepG2 cells and reversing hyperlipidemia in a mouse model of diet-induced obesity. In a mouse model of diabetes, neohesperidin increases glucose tolerance and decreases insulin resistance while simultaneously decreasing serum triglycerides and total cholesterol and inhibiting lipid accumulation in livers in vivo.

Chemical Properties

White powder, easily soluble in methanol and almost insoluble in ether, derived from trifoliate orange peel, sour orange immature fruit, and various citrus fruits.

Uses

Neohesperidin exhibits lipid-regulating effects in vivo and in vitro. It is a main flavonoid in citrus byproducts (CBP) which possesses anti-oxidant activity.

Uses

Neohesperidin can be used in cosmetic products and as a sweetening agent in food & beverages, an antioxidant flavanone glycoside

Definition

ChEBI: Neohesperidin is a flavanone glycoside that is hesperitin having an 2-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety attached to the 7-hydroxy group. It has a role as an antineoplastic agent and a plant metabolite. It is a neohesperidoside, a disaccharide derivative, a dihydroxyflavanone, a member of 3'-hydroxyflavanones, a monomethoxyflavanone, a flavanone glycoside and a member of 4'-methoxyflavanones. It is functionally related to a hesperetin.

Neohesperidin Preparation Products And Raw materials

Raw materials

Preparation Products

Neosperidin dihydrochalcone

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Neohesperidin Suppliers

Americas 1 Canada 1 China 340 China Hong Kong 1 Europe 1 France 2 Germany 4 India 6 Japan 2 Switzerland 1 United Kingdom 9 United States 36 USA 1 Global 405

TOKYO CHEMICAL INDUSTRY CO., LTD.

Tel: 03-36680489
Fax: 03-3668-0520
Email: Sales-JP@TCIchemicals.com
Country: Japan
ProdList: 28387
Advantage: 80

Nacalai Tesque, Inc.

Tel: --
Fax: --
Email: info-tech@nacalai.co.jp
Country: Japan
ProdList: 6046
Advantage: 75

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View Lastest Price from Neohesperidin manufacturers

Changsha Staherb Natural Ingredients Co., Ltd.

Product: Neohesperidin 13241-33-3
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 95%, 98%
Supply Ability: 1000kg
Release date: 2022-10-08

Watson Biotechnology Co.,Ltd

Product: Neohesperidin 13241-33-3
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 20MT
Release date: 2024-09-19

BINBO BIOLOGICAL CO.,LTD

Product: Neohesperidin 13241-33-3
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1000 kg
Release date: 2024-04-24

13241-33-3, NeohesperidinRelated Search:

Hesperetin Diethylstilbestrol HESPERIDINASE Hesperidin Methyl hesperidin Neosperidin dihydrochalcone 1-(4-PROPOXY-PHENYL)-ETHANONE 4-N-BUTOXYBENZALDEHYDE 4-CHROMANONE BETA-PHENYLPROPIOPHENONE 7-METHOXYFLAVANONE PHENYL-BETA-D-GLUCOPYRANOSIDE 3-Butoxyphenol L-LYXOSE PINOCEMBRIN 3'-HYDROXYFLAVANONE 7-HYDROXYFLAVANONE Diethylene glycol monobutyl ether

HESPERETIN-7-NEOHESPERIDOSIDE

HESPERETIN-7-O-NEOHESPERIDOSIDE

Neohesperidin HPLC 96% Min

(s)-a-d-glucopyranosyl)oxy)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)

4h-1-benzopyran-4-one,2,3-dihydro-7-((2-o-(6-deoxy-alpha-l-mannopyranosyl)-bet

Neohesperidin≥ 98% (HPLC)

7-[[4,5-dihydroxy-6-(hydroxymethyl)-3-[(3,4,5-trihydroxy-6-methyl-2-oxanyl)oxy]-2-oxanyl]oxy]-5-hydroxy-2-(3-hydroxy-5-methoxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one

Neohesperidin 95% HPLC

(S)-7-(((2-O-6-Deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one

(S)-4'-METHOXY-3',5,7-TRIHYDROXYFLAVONE-7-[2-O-(ALPHA-L-RHAMNOPYRANOSYL)-BETA-D-GLUCOPYRANOSIDE]

NEOHESPERIDIN

NEOHESPERIDIN (PR)

(S)-7-[[2-O-6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one

Neohesperdin

(s)-4'-methoxy-3',5,7-trihydroxyflavanone-7-[2-o-(α-l-rhamnopyranosyl)-β-d-glucopyranoside]

NEOHESPERIDIN WITH HPLC

rhamnopyranosyl-(1→2)-β-D-glucopyranoside

Neohesperidin，Hesperetin 7-neohesperidoside

(2S)-2-(3-Hydroxy-4-methoxyphenyl)-5-hydroxy-7-(2-O-α-L-rhamnopyranosyl-β-D-glucopyranosyloxy)-2,3-dihydro-4H-1-benzopyran-4-one

(2S)-7-[[2-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one

Neohesperidin, 98%, from Poncirus trifoliata (L.) Raf.

4H-1-Benzopyran-4-one,7-[[2-O-(6-deoxy-a-L-mannopyranosyl)-b-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-,(2S)-

(2S)-Neohesperidin

NSC 31048

HESPERETIN-7-NEOHESPERIDOSIDE hplc

Neohesperidin, froM Poncirus trifoliata(L.)Raf.

Neohesperidin Standard

4H-1-Benzopyran-4-one, 7-[[2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-, (2S)-

(S)-7-(((2S,3R,4S,5S,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)chroman-4-one

Hesperidin Impurity 9

(2S)-7-[2-O-(6-Deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyloxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one

Neohesperidin USP/EP/BP

Businessperson

(2S)-7-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-2,3-dihydrochromen-4-one

Neohesperidin (Hesperetin 7-O-neohesperidoside)

Neohesperidin, 90%+

Neohesperidin ((S)-5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl 2-O-(a (1458042)

(2S)-7-{[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}oxan-2-yl]oxy}-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one

Neohesperidin (6CI, 8CI)

(2RS)-7-[[2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-2,3-dihydro-4H-1-benzopyran-4-one (neohesperidin)

Citrus Polyphenols

4H-1-Benzopyran-4-one, 7-[[2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-, (2S)-

Neohesperidin-RM

13241-33-3

C28H34O15

Natural Dyes

Disaccharide

Carbohydrates

Biochemicals and Reagents

BioChemical

CITRIMORE

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract

Flavanones

Inhibitors