ETHYL 3-AMINOCROTONATE
- Product Name
- ETHYL 3-AMINOCROTONATE
- CAS No.
- 626-34-6
- Chemical Name
- ETHYL 3-AMINOCROTONATE
- Synonyms
- (Z)-3-aminobut-2-enoate;(Z)-ETHYL 3-AMINOBUT-2-ENOATE;AURORA KA-7376;Ethyl 3-aMinocroton;3-amino-2-hexenoate;ETHYL 3-AMINOCROTONA;Impurity of nifedipine;Ethyl (Z)-3-aminocrotonate;Ethyl 3-aminocrotonate 98%;(Z)-Ethyl 3-aminocrotonate
- CBNumber
- CB6302533
- Molecular Formula
- C6H11NO2
- Formula Weight
- 129.16
- MOL File
- 626-34-6.mol
ETHYL 3-AMINOCROTONATE Property
- Melting point:
- 33-35 °C (lit.)
- Boiling point:
- 210-215 °C (lit.)
- Density
- 1.022 g/mL at 25 °C (lit.)
- refractive index
- 1.4990
- Flash point:
- 207 °F
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- pka
- 5.32±0.70(Predicted)
- Appearance
- Off-white to light yellow <33°C Solid,>35°C Liquid
- Water Solubility
- Soluble in water (26 g/L) (25°C).
- Sensitive
- Air & Moisture Sensitive & Hygroscopic
- BRN
- 471284
- InChI
- InChI=1S/C6H11NO2/c1-3-9-6(8)4-5(2)7/h4H,3,7H2,1-2H3/b5-4-
- InChIKey
- YPMPTULBFPFSEQ-PLNGDYQASA-N
- SMILES
- C(OCC)(=O)/C=C(\N)/C
- LogP
- 0.390 (est)
- CAS DataBase Reference
- 626-34-6(CAS DataBase Reference)
Safety
- Hazard Codes
- C
- Risk Statements
- 34-36/37
- Safety Statements
- 26-27-28-36/37/39-45
- RIDADR
- UN 3263 8/PG 2
- WGK Germany
- 3
- HazardClass
- 8
- PackingGroup
- III
- HS Code
- 29224999
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
H335May cause respiratory irritation
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- E10807
- Product name
- Ethyl 3-aminocrotonate
- Purity
- 98%
- Packaging
- 100g
- Price
- $56.5
- Updated
- 2025/07/31
- Product number
- E10807
- Product name
- Ethyl 3-aminocrotonate
- Purity
- 98%
- Packaging
- 500g
- Price
- $154
- Updated
- 2023/06/20
- Product number
- C960
- Product name
- Ethyl 3-aminocrotonate
- Packaging
- 25g
- Price
- $34
- Updated
- 2021/12/16
- Product number
- APN0000366
- Product name
- (Z)-ETHYL 3-AMINOBUT-2-ENOATE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $121.8
- Updated
- 2021/12/16
- Product number
- OR936394
- Product name
- Ethyl 3-aminocrotonate
- Purity
- 95%
- Packaging
- 100g
- Price
- $124
- Updated
- 2021/12/16
ETHYL 3-AMINOCROTONATE Chemical Properties,Usage,Production
Uses
Ethyl 3-aminocrotonate, is used as an intermediate in organic synthesis. It is also used as an active ingredient in pharmaceutical synthesis and feed auxiliary agent. It is also used as an active pharmaceutical intermediate.
Synthesis
141-97-9
626-34-6
Example 9: Preparation of ethyl 3-aminocrotonate was carried out using continuous flow experiments. The experiments were carried out in a 1.58 mm OD SS316 tubular reactor. By using a simple T-mixer and a 1 m long reactor, ethyl acetoacetate was mixed with ammonia (25% solution) in a ratio of 1:3 with a residence time of 22 min. The yield of the product ethyl 3-aminocrotonate was 94% at 50 °C.
References
[1] Comptes Rendus Chimie, 2011, vol. 14, # 5, p. 511 - 515
[2] Patent: WO2012/147103, 2012, A2. Location in patent: Page/Page column 7
[3] Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1986, vol. 35, p. 1438 - 1442
[4] Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1986, # 7, p. 1586 - 1592
[5] European Journal of Medicinal Chemistry, 2018, vol. 155, p. 946 - 960
ETHYL 3-AMINOCROTONATE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from ETHYL 3-AMINOCROTONATE manufacturers
- Product
- ETHYL 3-AMINOCROTONATE 626-34-6
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-11
- Product
- ETHYL 3-AMINOCROTONATE 626-34-6
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09
- Product
- ETHYL 3-AMINOCROTONATE 626-34-6
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-27