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2,2'-Oxybis(nitrobenzene)

Product Name
2,2'-Oxybis(nitrobenzene)
CAS No.
2217-65-4
Chemical Name
2,2'-Oxybis(nitrobenzene)
Synonyms
Olanzapine Impurity 26;Olanzapine Impurity 34;2,2'-Oxybis(nitrobenzene);2,2'-Oxybis(nitrobenzdene);Benzene, 1,1'-oxybis[2-nitro-
CBNumber
CB63037742
Molecular Formula
C12H8N2O5
Formula Weight
260.2
MOL File
2217-65-4.mol
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2,2'-Oxybis(nitrobenzene) Property

Melting point:
114.5 °C
Boiling point:
185 °C(Press: 15 Torr)
Density 
1.416±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
O990158
Product name
2,2''-Oxybis(nitrobenzdene)
Packaging
50mg
Price
$45
Updated
2021/12/16
TRC
Product number
O990158
Product name
2,2''-Oxybis(nitrobenzdene)
Packaging
100mg
Price
$60
Updated
2021/12/16
AK Scientific
Product number
1858AL
Product name
2,2'-Oxybis(nitrobenzene)
Packaging
10g
Price
$849
Updated
2021/12/16
Ambeed
Product number
A384376
Product name
2,2'-Oxybis(nitrobenzene)
Purity
95%
Packaging
100mg
Price
$21
Updated
2021/12/16
Ambeed
Product number
A384376
Product name
2,2'-Oxybis(nitrobenzene)
Purity
95%
Packaging
250mg
Price
$33
Updated
2021/12/16
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2,2'-Oxybis(nitrobenzene) Chemical Properties,Usage,Production

Synthesis

1493-27-2

2217-65-4

General procedure: 1-fluoro-2-nitrobenzene (1.0 mmol) was used as a feedstock, and tributylphosphine (PBu3, 2.0 mmol), palladium acetate (Pd(OAc)2, 2 mol%), and potassium carbonate/zirconium oxide (K2CO3/ZrO2, 1.5 equiv, based on K2CO3, 2.070 g) were added in xylene (10 mL). The mixture was stirred at reflux under nitrogen protection for 24 hours or until TLC showed that the reaction was complete. After completion of the reaction, the mixture was filtered and washed with dichloromethane (DCM). The organic layers were combined and the solvent was removed by evaporation. The product was purified by column chromatography using dichloromethane/hexane (1:1 to 1:2) as eluent to give the target product 2,2'-oxobis(nitrobenzene).

References

[1] Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1992, # 3, p. 377 - 382
[2] Chemistry - An Asian Journal, 2015, vol. 10, # 2, p. 468 - 473
[3] Journal of Chemical Research, 2016, vol. 40, # 11, p. 691 - 693
[4] Journal of Organic Chemistry, 2018, vol. 83, # 24, p. 14882 - 14893

2,2'-Oxybis(nitrobenzene) Preparation Products And Raw materials

Raw materials

Preparation Products

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