Sitagliptin EP Impurity B

Product Name: Sitagliptin EP Impurity B
CAS No.: 1345822-87-8
Chemical Name: Sitagliptin EP Impurity B
Synonyms: 4-Desfluoro Sitagliptin;Sitagliptin EP Impurity B;Sitagliptin?4-Desfluoro?Impurity;4-Desfluoro Sitagliptin Phosphate;Sitagliptin EP Impurity B Phosphate;Sitagliptin EP Impurity B / Sitagliptin 4-Desfluoro Impurity;(R)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,5-difluorophenyl)butan-2-amine phosphate;(R)-7-[3-Amino-1-oxo-4-(2,5-difluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine phosphate (1:1);(R)-3-Amino-4-(2,5-difluorophenyl)-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)butan-1-one phosphate? (Sitagliptin Impurity);Sitagliptin impurity 3/Sitagliptin EP Impurity B/Sitagliptin 4-Desfluoro Impurity/(R)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,5-difluorophenyl)butan-2-amine phosphate
CBNumber: CB63050608
Molecular Formula: C16H19F5N5O5P
Formula Weight: 487.318337
MOL File: 1345822-87-8.mol

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Sitagliptin EP Impurity B Property

InChIKey: UOKMPNRCGWVMBY-XAAIUDFWNA-N
SMILES: P(O)(O)(O)=O.C(N1CCN2C(C(F)(F)F)=NN=C2C1)(=O)C[C@H](N)CC1=CC(F)=CC=C1F |&1:21,r|

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: D290360
Product name: 4-DesfluoroSitagliptin
Packaging: 25mg
Price: $1320
Updated: 2021/12/16

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Sitagliptin EP Impurity B Chemical Properties,Usage,Production

Uses

4-Desfluoro Sitagliptin is a metabolite of Sitagliptin phosphate (S491000). Sitagliptin is a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes.

Uses

Sitagliptin EP Impurity B is an impurity of the synthetic drug Sitagliptin. It can be used as an impurity reference to detect the quality of drugs, and is often used in pharmaceutical synthesis. Sitagliptin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in people with type 2 diabetes. Sitagliptin is not for treating type 1 diabetes

Sitagliptin EP Impurity B Preparation Products And Raw materials

Raw materials

Preparation Products

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Sitagliptin EP Impurity B Suppliers

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1345822-87-8, Sitagliptin EP Impurity BRelated Search:

7-[(3R)-3-[(N-Acetyl)AMino]-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoroMethyl)-1,2,4-triazolo[4,3-a]pyrazine rac-Sitagliptin EP Impurity B HCl rac-Sitagliptin n-(3-dimethylaminopropyl)-n'-ethylcarbodiimide hydrochloride Benzenebutanoicacid,b-aMino-2,4,5-trifluoro-,Methylester,(bR)- 2-(3-(methylamino)-1-(thiophen-2-yl)propyl)naphthalen-1-ol Sitagliptin Impurity 34 2,4,5-Trifluorobenzaldehyde 1,2,4-Triazolo[4,3-a]pyrazine, 7-[3-amino-1-oxo-4-(2,4,5-trifluorophenyl)-2-butenyl]-5,6,7,8-tetrahydro- 3-(trifluoromethyl)- Sitagliptin Methyl 3-Oxo-4-(2,4,5-trifluorophenyl)butanoate (R)-10-(2,4,5-trifluorobenzyl)-3-(trifluoromethyl)-6,7,10,11-tetrahydro-[1,2,4]triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione Sitagliptin N-Sulfate BOC-(S)-3-AMINO-4-(2,4,5-TRIFLUORO-PHENYL)-BUTYRIC ACID Methyl 3-acetamido-4-(2,4,5-trifluorophenyl)but-2-enoate Sitagliptin N-Boc IMpurity Sitagliptin Impurity 35 (S)-Sitagliptin Phosphate

Sitagliptin EP Impurity B

Sitagliptin impurity 3/Sitagliptin EP Impurity B/Sitagliptin 4-Desfluoro Impurity/(R)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,5-difluorophenyl)butan-2-amine phosphate

4-Desfluoro Sitagliptin

(R)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,5-difluorophenyl)butan-2-amine phosphate

4-Desfluoro Sitagliptin Phosphate

Sitagliptin EP Impurity B Phosphate

Sitagliptin EP Impurity B / Sitagliptin 4-Desfluoro Impurity

Sitagliptin?4-Desfluoro?Impurity

(R)-7-[3-Amino-1-oxo-4-(2,5-difluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine phosphate (1:1)

(R)-3-Amino-4-(2,5-difluorophenyl)-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)butan-1-one phosphate? (Sitagliptin Impurity)

1345822-87-8