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m-PEG10-amine

Product Name
m-PEG10-amine
CAS No.
1383658-09-0
Chemical Name
m-PEG10-amine
Synonyms
m-PEG10-amine;3,6,9,12,15,18,21,24,27,30-Decaoxahentriacontan-1-amine;2,5,8,11,14,17,20,23,26,29-Decaoxahentriacontan-31-amine;mPEG10-NH2/3,6,9,12,15,18,21,24,27,30-Decaoxahentriacontan-1-amine
CBNumber
CB63062559
Molecular Formula
C21H45NO10
Formula Weight
471.58
MOL File
1383658-09-0.mol
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m-PEG10-amine Property

Boiling point:
518.9±45.0 °C(Predicted)
Density 
1.065±0.06 g/cm3(Predicted)
pka
8.74±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
P999895
Product name
M-PEG10-Amine
Packaging
100mg
Price
$240
Updated
2021/12/16
Activate Scientific
Product number
AS104094
Product name
mPEG10-NH2
Purity
95+%
Packaging
250mg
Price
$350
Updated
2021/12/16
BroadPharm
Product number
BP-22079
Product name
m-PEG10-amine
Purity
98%
Packaging
500mg
Price
$390
Updated
2021/12/16
Activate Scientific
Product number
AS104094
Product name
mPEG10-NH2
Purity
95+%
Packaging
1g
Price
$673
Updated
2021/12/16
Apolloscientific
Product number
BIPG1588
Product name
m-PEG10-amine
Packaging
500mg
Price
$931
Updated
2021/12/16
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m-PEG10-amine Chemical Properties,Usage,Production

Description

m-PEG10-amine is reactive with activated NHS esters to form stable aminde bond. The hydrophilic PEG spacer increases solubility in aqueous media.

Biological Activity

m-PEG10-amine is a non-cleavable ADC linker containing 10 units of PEG, which can be used for the synthesis of antibody drug conjugates (ADCs). It is also a PROTAC linker, belonging to the PEG class, which can be used to synthesize PROTAC molecules.

in vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

target

PEGs

Non-cleavable

m-PEG10-amine Preparation Products And Raw materials

Raw materials

Preparation Products

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m-PEG10-amine Suppliers

Apollo Scientific Ltd.
Tel
--
Fax
--
Email
sales@apolloscientific.co.uk
Country
United Kingdom
ProdList
6084
Advantage
88
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View Lastest Price from m-PEG10-amine manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
m-PEG10-amine 1383658-09-0
Price
US $0.00/g
Min. Order
1g
Purity
>98.00%
Supply Ability
1g
Release date
2024-03-27