m-PEG10-amine
- Product Name
- m-PEG10-amine
- CAS No.
- 1383658-09-0
- Chemical Name
- m-PEG10-amine
- Synonyms
- m-PEG10-amine;3,6,9,12,15,18,21,24,27,30-Decaoxahentriacontan-1-amine;2,5,8,11,14,17,20,23,26,29-Decaoxahentriacontan-31-amine;mPEG10-NH2/3,6,9,12,15,18,21,24,27,30-Decaoxahentriacontan-1-amine
- CBNumber
- CB63062559
- Molecular Formula
- C21H45NO10
- Formula Weight
- 471.58
- MOL File
- 1383658-09-0.mol
m-PEG10-amine Property
- Boiling point:
- 518.9±45.0 °C(Predicted)
- Density
- 1.065±0.06 g/cm3(Predicted)
- pka
- 8.74±0.10(Predicted)
N-Bromosuccinimide Price
- Product number
- P999895
- Product name
- M-PEG10-Amine
- Packaging
- 100mg
- Price
- $240
- Updated
- 2021/12/16
- Product number
- AS104094
- Product name
- mPEG10-NH2
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $350
- Updated
- 2021/12/16
- Product number
- BP-22079
- Product name
- m-PEG10-amine
- Purity
- 98%
- Packaging
- 500mg
- Price
- $390
- Updated
- 2021/12/16
- Product number
- AS104094
- Product name
- mPEG10-NH2
- Purity
- 95+%
- Packaging
- 1g
- Price
- $673
- Updated
- 2021/12/16
- Product number
- BIPG1588
- Product name
- m-PEG10-amine
- Packaging
- 500mg
- Price
- $931
- Updated
- 2021/12/16
m-PEG10-amine Chemical Properties,Usage,Production
Description
m-PEG10-amine is reactive with activated NHS esters to form stable aminde bond. The hydrophilic PEG spacer increases solubility in aqueous media.
Biological Activity
m-PEG10-amine is a non-cleavable ADC linker containing 10 units of PEG, which can be used for the synthesis of antibody drug conjugates (ADCs). It is also a PROTAC linker, belonging to the PEG class, which can be used to synthesize PROTAC molecules.
in vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
target
PEGs
| Non-cleavable
|
m-PEG10-amine Preparation Products And Raw materials
Raw materials
Preparation Products
m-PEG10-amine Suppliers
- Tel
- --
- Fax
- --
- sales@apolloscientific.co.uk
- Country
- United Kingdom
- ProdList
- 6084
- Advantage
- 88
View Lastest Price from m-PEG10-amine manufacturers
- Product
- m-PEG10-amine 1383658-09-0
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-27