Derazantinib Property

Boiling point:

615.1±65.0 °C(Predicted)

Density 

1.218±0.06 g/cm3(Predicted)

storage temp. 

Store at -20°C

solubility 

DMSO:47.67(Max Conc. mg/mL);101.73(Max Conc. mM)
DMF:30.0(Max Conc. mg/mL);64.02(Max Conc. mM)
DMF:PBS (pH 7.2) (1:3):0.25(Max Conc. mg/mL);0.53(Max Conc. mM)

form 

A crystalline solid

pka

9.04±0.19(Predicted)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

Derazantinib Chemical Properties,Usage,Production

Uses

Derazantinib is an intermediate in the preparation of imidazopyridinyl compounds for treating proliferative disorders like cancer, Proteus syndrome and others.