4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]-N-methylbenzamide

ChemicalBook > CAS DataBase List > 4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]-N-methylbenzamide

4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]-N-methylbenzamide

Product Name: 4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]-N-methylbenzamide
CAS No.: 915087-16-0
Chemical Name: 4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]-N-methylbenzamide
Synonyms: EZ-TFAPI;EZLA-API;Desfluoroenzalutamide;Defluoro-enzalutamide;Enzalutamide Impurity 5;Enzalutamide Des Fluoro-EZD;Enzalutamide Desfluoro impurity;Enzalutamidedefluorinationimpurity;Enzalutamide Impurity I/ Enzalutamide Desfluoro impurity;4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]-N-methylbenzamide
CBNumber: CB63154988
Molecular Formula: C21H17F3N4O2S
Formula Weight: 446.45
MOL File: 915087-16-0.mol

Less

4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]-N-methylbenzamide Property

Density: 1.46±0.1 g/cm3(Predicted)
solubility: Acetone (Slightly), Chloroform (Slightly)
pka: 14.46±0.46(Predicted)
form: Solid
color: Pale Yellow to Light Yellow

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H360May damage fertility or the unborn child

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

Less

N-Bromosuccinimide Price

TRC

Product number: D228590
Product name: Defluoro-MDV3100(Defluoro-enzalutamide)
Packaging: 10mg
Price: $75
Updated: 2021/12/16

Less

4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]-N-methylbenzamide Chemical Properties,Usage,Production

Uses

Defluoro-MDV 3100 (Defluoro-enzalutamide) is an impurity of Enzalutamide (M199800), which is an androgen-receptor antagonist that blocks androgens from binding to the androgen receptor and prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex. Enzalutamide has been shown to induce tumor cell apoptosis, and is used for the treatment of castration-resistant prostate cancer.

4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]-N-methylbenzamide Preparation Products And Raw materials

Raw materials

Preparation Products

Less

4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]-N-methylbenzamide Suppliers

China 56 India 5 United States 1 Global 62

Beijing Comparison Pharmaceutical Technology Co., Ltd

Tel: 010-010-52878169 15801002657
Email: sales@bjcomparison.com
Country: China
ProdList: 4846
Advantage: 58

Shanghai Famo Bio-chemical Technology Company Ltd.

Tel: 021-36680027 15821745250
Email: fengqiang@famobiotech.com
Country: China
ProdList: 563
Advantage: 56

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 18110
Advantage: 56

Shanghai Kewel Chemical Co., Ltd.

Tel: 021-64609169 18901607656
Fax: 021-64609160
Email: greensnown@163.com
Country: China
ProdList: 9906
Advantage: 50

Nanjing XiZe Biotechnology CO., Ltd.

Tel: 025-66023220 0086-15250997978
Fax: 025-58362220
Email: 1511893459@qq.com
Country: China
ProdList: 7888
Advantage: 55

Shanghai SuperLan Chemcial Technique Centre

Tel: 021-2022843681 15618226720
Fax: +86-21-51601218
Email: lucy@atkchemical.com
Country: China
ProdList: 10979
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Shanghai XingTai Pharmaceutical Technology co., LTD

Tel: 15801747407
Fax: +86 021 51388225
Email: sales01@suntechpharma.com
Country: China
ProdList: 123
Advantage: 58

Sichuan jiayinglai technology CO.,LTD

Tel: 028-028-88457210 18054780191
Fax: QQ3213375147
Email: 551604319@qq.com
Country: China
ProdList: 2294
Advantage: 55

Conier Chem & Pharma Limited

Tel: 13368167990
Email: sales@conier.com
Country: China
ProdList: 2839
Advantage: 58

Zhengzhou Acme Chemical Co., Ltd.

Tel: 0371-037163312495,13303845143 13303845143
Fax: QQ3001379618
Email: 3001379618@qq.com
Country: China
ProdList: 10347
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57422
Advantage: 58

Shenzhen Botel Biotechnology Co. Ltd.

Tel: 13316949107 13316968096
Email: 1979313431@qq.com
Country: China
ProdList: 9224
Advantage: 58

sgtlifesciences pvt ltd

Tel: +8617013299288
Email: dj@sgtlifesciences.com
Country: China
ProdList: 12373
Advantage: 58

Guangzhou Dreampharm Biotechnology Co., Ltd.

Tel: 020-36607679 17825480238
Fax: QQ 3008233717
Email: 3008233746@qq.com
Country: China
ProdList: 9929
Advantage: 12

Tianjin shijia biomedical technology co., LTD

Tel: 15022261580
Email: tjshj1212@163.com
Country: China
ProdList: 2542
Advantage: 58

Jinan blalong chemical co. LTD

Tel: 2710913286@.com
Email: 1513643261@qq.com
Country: China
ProdList: 14246
Advantage: 58

Shenzhen ruikai de biotechnology co., ltd.

Tel: 0755-61348847 17820674378
Fax: 0755-21016893
Email: 2682116078@qq.com
Country: China
ProdList: 7843
Advantage: 58

Shenzhen Jianyi Biotechnology Co., Ltd

Tel: 0755-84826604
Email: 3001783715@qq.com
Country: CHINA
ProdList: 2896
Advantage: 58

Wuxi Helen Biotechnology Co., Ltd.,

Tel: 0510-85629785 18013409632
Fax: 0510-85625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 14081
Advantage: 58

Guangzhou Juntang Technology Co., Ltd

Tel: 020-36607679 13502246435
Email: sales@dmstandards.com
Country: China
ProdList: 10945
Advantage: 58

Jiangsu Wansipu Technology Co., Ltd.

Tel: 17826022701
Email: 1485609990@qq.com
Country: China
ProdList: 976
Advantage: 58

Hubei Yuanmeng Biotechnology Co., Ltd

Tel: 027-68897569 18120462897
Fax: 027-68897569
Email: fiona@yuanmengbio.com
Country: China
ProdList: 4121
Advantage: 58

TCI (Shanghai) Chemical Trading Co., Ltd.

Tel: 021-021-61109150
Fax: 021-61105897
Email: sales@tcisct.com
Country: China
ProdList: 31121
Advantage: 58

Changzhou Xianglong Pharmaceutical Technology Co., LTD

Tel: 0519-88910898 18661161657
Email: yaoxiangqiu2021@163.com
Country: China
ProdList: 9996
Advantage: 58

Molcoo Chemicals Inc.

Tel: 18576690171
Email: 3001025734@qq.com
Country: China
ProdList: 11429
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-1647117 13681763483
Email: product02@bidepharm.com
Country: China
ProdList: 62072
Advantage: 58

Wuhan haorong Biotechnology Co., Ltd

Tel: 13217229939
Email: 773651767@qq.com
Country: China
ProdList: 4550
Advantage: 58

Shenzhen Roark Pharma-Tec Co., Ltd.

Tel: 13128912434
Email: 2880126944@qq.com
Country: China
ProdList: 2577
Advantage: 58

Hubei Weideli Chemical Reagent Co.，Ltd.

Tel: 13339985473
Email: C13339985473@163.com
Country: China
ProdList: 4787
Advantage: 58

Hubei Weideli Chemical Reagent Co.，Ltd.

Tel: 027-59222918 13385289472
Email: Z13385289472@163.com
Country: China
ProdList: 4773
Advantage: 58

Scinova Biotech(Guangzhou) Co., Ltd.

Tel: 13268215580
Email: scinova_sales@163.com
Country: China
ProdList: 7025
Advantage: 58

Cato Research Chemicals Inc.

Tel: 020-81960175-877 18933936954
Email: tianwen.zhan@cato-chem.com
Country: China
ProdList: 7761
Advantage: 58

WEITIXIHAUGONG

Tel: 0371-53370800 18037197114
Email: 2853031799@qq.com
Country: China
ProdList: 10058
Advantage: 58

Shanghai YuZn Pharm. Technology Co.,Ltd.

Tel: 15921286451; 15921286451
Email: 2010681527@qq.com
Country: China
ProdList: 5116
Advantage: 58

Sichuan HongRi Pharma-Tech Co., Ltd

Tel: 18123311397
Fax: 0838-2822568
Email: 2065506070@qq.com
Country: China
ProdList: 2041
Advantage: 58

Shijiazhuang Kangxi Biotechnology Limited

Tel: 13803336640
Email: 3501227372@qq.com
Country: China
ProdList: 1247
Advantage: 58

Nanjing Huanuo Biomedical Technology Co., Ltd

Tel: 18913906212
Email: 2885426135@qq.com
Country: China
ProdList: 7228
Advantage: 58

Shanghai Haohong Scientific Co., Ltd.

Tel: 4008210725 17717813675;
Email: cb_no5@leyan.com
Country: China
ProdList: 40112
Advantage: 58

LangFangshi Zekang Pharma Tech CO.,Itd.

Tel: 0316-2883536 19333636468
Email: 93618484@qq.com
Country: China
ProdList: 1505
Advantage: 58

Tan-Mo Technology Co., Ltd.

Tel: 19850211281
Email: qiann@gbw-china.com
Country: China
ProdList: 1980
Advantage: 58

JiNan QiYuan Biotechnology Co., Ltd

Tel: 18766124282; 18766124282
Email: 18766124282@163.COM
Country: China
ProdList: 884
Advantage: 58

Hubei De'ao Chemical Research Pharmaceutical Technology Co., Ltd

Tel: 18502726233; 18502726233
Email: 3641133981@qq.com
Country: China
ProdList: 9713
Advantage: 58

Shenzhen Qingtian Biotechnology Co, Ltd.

Tel: 18823167005 18162969855
Email: 744288988@qq.com
Country: China
ProdList: 2629
Advantage: 58

Hubei Soren Technology Co., Ltd

Tel: 0-13419562052 13419562052
Email: wwmlyb@163.com
Country: China
ProdList: 3277
Advantage: 58

Guangzhou Zhenlin Pharmaceutical Technology Co., Ltd

Tel: 13500006345; 13500006345
Email: LK@zlstandards.com
Country: China
ProdList: 7660
Advantage: 58

Pushan Industry (Shaanxi) Co., Ltd

Tel: 029-81310890 18165209495
Email: 2929288192@qq.com
Country: China
ProdList: 10002
Advantage: 58

Nantong Hanfang Biotechnology Co. , Ltd.

Tel: 18616537568
Email: hanfangpharma@126.com
Country: China
ProdList: 29981
Advantage: 58

Cato Research Chemicals Inc.

Tel: 13342851930
Email: 2853283383@qq.com
Country: China
ProdList: 15726
Advantage: 58

Shanghai Daken Advanced Materials Co.,Ltd

Tel: +86-371-+86-371-66670886
Email: info@dakenam.com
Country: China
ProdList: 19825
Advantage: 58

915087-16-0, 4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]-N-methylbenzamideRelated Search:

Enzalutamide Impurity 20 4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluorobenzoic acid methyl ester Enzalutamide EnzalutaMide IMpurity methyl 2-fluoro-4-((1-methoxy-2-methyl-1-oxopropan-2-yl)amino)benzoate 4-Bromo-2-fluorobenzoic acid 4-[3-[4-Cyano-3-(trifluoroMethyl)phenyl]-5,5-diMethyl-4-oxo-2-thioxo-1-iMidazolidinyl]-2-fluoro-N-(Methyl-d3)benzaMide Enzalutamide Methyl 4-bromo-2-fluorobenzoate 4-(2-CYANOPROPAN-2-YLAMINO)-2-FLUORO-N-METHYLBENZAMIDE Enzalutamide carboxylic acid N-desMethyl EnzalutaMide [2H6]-Enzalutamide Enzalutamide Impurity 7 4-isothiocyanato-2-(trifluoroMethyl)benzonitrile Enzalutamide Impurity 7 4-[1-(4-cyano-3-trifluoromethyl-phenylcarbamoyl)-1-methyl-ethylamino]-2-fluoro-N- 4-amino-2-fluoro-N-methylbenzamide

Enzalutamide Impurity 5

Defluoro-enzalutamide

4-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]-N-methylbenzamide

4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]-N-methylbenzamide

Enzalutamide Des Fluoro-EZD

Desfluoroenzalutamide

Enzalutamide Desfluoro impurity

Enzalutamide Impurity I/ Enzalutamide Desfluoro impurity

EnzalutamideImpurityIQ: What is EnzalutamideImpurityI Q: What is the CAS Number of EnzalutamideImpurityI Q: What is the storage condition of EnzalutamideImpurityI Q: What are the applications of EnzalutamideImpurityI

EZ-TFAPI

Benzamide, 4-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-N-methyl-

4-(3-(4-cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-N-methylbenzamide? (Enzalutamide Impurity）

EZLA-API

Enzalutamidedefluorinationimpurity

915087-16-0