Edoxaban-d6

Product Name: Edoxaban-d6
CAS No.: 1304701-57-2
Chemical Name: Edoxaban-d6
Synonyms: Edoxaban-d6;[2H6]-Edoxaban;Edoxaban hydrochloride salt;N-[(1S,2R,4S)-4-[bis(trideuteriomethyl)carbamoyl]-2-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carbonyl)amino]cyclohexyl]-N'-(5-chloropyridin-2-yl)oxamide
CBNumber: CB63163409
Molecular Formula: C24H30ClN7O4S
Formula Weight: 548.06
MOL File: 1304701-57-2.mol

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Edoxaban-d6 Property

Melting point:: >205°C (dec.)
storage temp.: Hygroscopic, Refrigerator, under inert atmosphere
solubility: Chloroform (Slightly), Dichloromethane (Slightly)
form: Solid
color: Pale Orange to Pale Red
Stability:: Hygroscopic

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 25760
Product name: Edoxaban-d6
Purity: ≥99% deuterated forms (d1-d6)
Packaging: 500μg
Price: $396
Updated: 2024/03/01

Cayman Chemical

Product number: 25760
Product name: Edoxaban-d6
Purity: ≥99% deuterated forms (d1-d6)
Packaging: 1mg
Price: $711
Updated: 2024/03/01

Usbiological

Product number: 448076
Product name: Edoxaban-d6
Packaging: 500ug
Price: $531
Updated: 2021/12/16

TRC

Product number: E555522
Product name: Edoxaban-d6
Packaging: 5mg
Price: $1850
Updated: 2021/12/16

AK Scientific

Product number: 4287DK
Product name: N-[(1S,2R,4S)-4-[Bis(trideuteriomethyl)carbamoyl]-2-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carbonyl)amino]cyclohexyl]-N'-(5-chloropyridin-2-yl)oxamide
Packaging: 1mg
Price: $889
Updated: 2021/12/16

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Edoxaban-d6 Chemical Properties,Usage,Production

Description

Edoxaban-d₆ is intended for use as an internal standard for the quantification of edoxaban by GC- or LC-MS. Edoxaban is an orally bioavailable and potent inhibitor of factor Xa (K_is = 0.561 and 0.903 nM for free and complexed human factor Xa, respectively). It is >10,000-fold selective for factor Xa over thrombin, FVIIa/sTF, FXIa, tPA, aPC, trypsin, plasmin, and chymotrypsin. Edoxaban prolongs prothrombin, activated partial thromboplastin, and thrombin clotting times in a concentration-dependent manner ex vivo in human plasma. Oral administration of edoxaban (0.5-12.5 mg/kg) reduces thrombus formation and prolongs prothrombin time in a dose-dependent manner in rat and rabbit models of venous stasis thrombosis. It also reduces thrombus formation in a rat model of platinum wire-induced venous thrombosis. Formulations containing edoxaban have been used to prevent stroke in patients with atrial fibrillation.

Uses

Edoxaban-d6 is the isotope labelled analog of Edoxaban (E555520); an anticoagulant drug which acts as a direct factor Xa inhibitor.

Edoxaban-d6 Preparation Products And Raw materials

Raw materials

Preparation Products

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Edoxaban-d6 Suppliers

Canada 1 China 19 India 4 United States 3 Global 27

Daicel Chiral Technologies (China)CO.,LTD

Tel: 021-50460086-9 15921403865
Fax: +86-21-50462321
Email: han_yajun@dctc.daicel.com
Country: China
ProdList: 7195
Advantage: 65

Artis Biotech Co. Ltd.

Tel: 0575-18780151478 18582380095
Fax: 0575-89298961
Email: sales@artisbio.com
Country: China
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Shanghai Han-Xiang Chemical Co., Ltd.

Tel: 15971444841
Fax: 18327183813
Email: amber@biochempartner.com
Country: China
ProdList: 3061
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Shenzhen Popeye Biotechnology Co. Ltd.

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Email: popeye02@qq.com
Country: China
ProdList: 310
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Jinan blalong chemical co. LTD

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ChemeGen(Shanghai) Biotechnology Co.,Ltd.

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Shenzhen ruikai de biotechnology co., ltd.

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Energy Chemical

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Manhag Testing Technology Co., Ltd

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Cato Research Chemicals Inc.

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Shanghai Yifei Biotechnology Co. , Ltd.

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Shanghai Beiwanta Biotechnology Co., Ltd.

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Nanjing Shizhou Biology Technology Co.,Ltd

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Nantong Hanfang Biotechnology Co. , Ltd.

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TargetMol Chemicals Inc.

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SHANGHAI ZZBIO CO., LTD.

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Cato Research Chemicals Inc.

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Shanghai Hao Zhun Biological Technology Co., Ltd.

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1304701-57-2, Edoxaban-d6Related Search:

2-(((1S,2R,4S)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)amino)-2-oxoacetic acid EthanediaMide, N1-(5-chlo... 2-BroMo-5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride EthanediaMide, N1-(5-chloro-2-pyridinyl)-N2-[(1R,2S,4S)-4-[(diMethylaMino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-Methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]aMino]cyclohexyl]- EthanediaMide iMpurity D EthanediaMide, N1-(5-chlo... tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate Ethyl 2-((5-chloropyridin-2-yl)amino)-2-oxoacetate hydrochloride EthanediaMide, N1-(5-chlo... Edoxaban (tosylate Monohydrate) EthanediaMide, N1-(5-chloro-2-pyridinyl)-N2-[(1S,2R,4R)-4-[(diMethylaMino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-Methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]aMino]cyclohexyl]- EthanediaMide, N1-(5-chlo... Edoxaban Impurity 16 (1S,3S,4S)-3-AMino-4-hydroxy-cyclohexanecarboxylic acid ethyl ester EthanediaMide, N1-(5-chloro-2-pyridinyl)-N2-[(1S,2S,4R)-4-[(diMethylaMino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-Methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]aMino]cyclohexyl]- (1S,3R,4S)-4-(2-((5-chloropyridin- 2-yl)amino)-2-oxoacetamido)-3-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexane-1-carboxylic acid (1R,3R,4R)-3-AMino-4-hydroxy-cyclohexanecarboxylic acid ethyl ester

Edoxaban-d6

N-[(1S,2R,4S)-4-[bis(trideuteriomethyl)carbamoyl]-2-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carbonyl)amino]cyclohexyl]-N'-(5-chloropyridin-2-yl)oxamide

[2H6]-Edoxaban

Edoxaban hydrochloride salt

1304701-57-2