ChemicalBook > CAS DataBase List > (4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate

(4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate

Product Name
(4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
CAS No.
125971-94-0
Chemical Name
(4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
Synonyms
ATS-8;(4R,CIS)-1,1-DIMETHYLETHYL-6-CYANOMETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE;(4R-CIS)-1,1-DIMETHYLETHYL-6-CYANOMETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE (ATS-8);tert-Butyl 2-((4R,6R)-6-(cyanoMethyl)-2,2-diMethyl-1,3-dioxan-4-yl)acetate;(4R,6R)-tert-Butyl-6;Atorvastatin Impurity 7;Atorvastatin calcium-11;Ats-8(For Atorvastatin);Atorvastatin Impurity 63;(4R,6R)-Tert-Butyl-6-Cyanometh
CBNumber
CB6327897
Molecular Formula
C14H23NO4
Formula Weight
269.34
MOL File
125971-94-0.mol
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(4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate Property

Melting point:
65-69 °C(lit.)
Boiling point:
364.1±17.0 °C(Predicted)
Density 
1.016±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
soluble in Chloroform
form 
powder to crystal
color 
White to Almost white
optical activity
[α]20/D 1.0°, c = 1 in chloroform
CAS DataBase Reference
125971-94-0(CAS DataBase Reference)
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Safety

Safety Statements 
24/25
WGK Germany 
3
HS Code 
29329990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
539015
Product name
tert-Butyl (4R,6R)-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
Purity
97%
Packaging
1g
Price
$48.4
Updated
2024/03/01
TCI Chemical
Product number
B3642
Product name
tert-Butyl (4R,6R)-6-Cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
Purity
>98.0%(GC)(N)
Packaging
5g
Price
$85
Updated
2024/03/01
TRC
Product number
C982020
Product name
(4R,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-aceticAcid1,1-DimethylethylEster
Packaging
500mg
Price
$110
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CCH0000262
Product name
(4R -CIS)-1, 1-DIMETHYLETHYL -6- CYANOMETHYL-2, 2-DIMETHYL-1, 3-DIOXANE-4-ACETATE
Purity
95.00%
Packaging
1G
Price
$123.9
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB32752
Product name
(4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
Packaging
25g
Price
$400
Updated
2021/12/16
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(4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powde

Uses

Atorvastatin Intermediate

Uses

(4R,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester is an intermediate of Atorvastatin (A791750, Ca salt), a selective, competitive HMG-CoA reductase . Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia.

(4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate Preparation Products And Raw materials

Raw materials

Preparation Products

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(4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate Suppliers

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View Lastest Price from (4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate manufacturers

hebei hongtan Biotechnology Co., Ltd
Product
(4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate 125971-94-0
Price
US $80.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000
Release date
2024-03-22
WUHAN FORTUNA CHEMICAL CO., LTD
Product
(4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate 125971-94-0
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-02-07
R&D Scientific Inc.
Product
(4R,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester 125971-94-0
Price
US $786.00/Kg
Min. Order
0.100Kg
Purity
99 %
Supply Ability
5000 Kg
Release date
2024-11-20

125971-94-0, (4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetateRelated Search:

Dimethyl fumarate Dimethyl sulfoxide Isobutyl acetate tert-Butanol tert-Butyl chloroacetate tert-Butyl acetate Dimethylbenzylcarbinyl acetate tert-Butyl bromoacetate N,N-Dimethylformamide DL-sec-Butyl acetate Methyl 2,2-dimethylphenylacetate Butyl acetate tert-Butyl peroxyacetate ETHANE (4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate Atorvastatin calcium Ethyl (R)-(-)-4-cyano-3-hydroxybutyate Atorvastatin

  • ATS-8
  • (4R,6R)-T-BUTYL-6-CYANOMETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE
  • (4R,6R)-TERT-BUTYL-6-CYANOMETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE
  • (4R,CIS)-1,1-DIMETHYLETHYL-6-CYANOMETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE
  • (4R,3R)-TERT-BUTYL-6-CYANOMETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE
  • (4R-CIS)-1,1-DIMETHYLETHYL-6-CYANOMETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE (ATS-8)
  • tert-Butyl (4R,3R)-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
  • TERT-BUTYL[(4R,6R)-6-CYANOMETHYL-2,2-DIMETHYL-1,3-DIOXAN-4-YL]ACETATE
  • (4R,6R)-t-butyl-6-cyanomethyl02,2-dimethyl-1,3-dioxane-4-acetate
  • (4R-cis)-1,1-dimethylethyl-6-cyanomethyl -2,2-dimethyl-1,3-dloxane-4-acetate
  • (4R,6R)-6-Cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetic Acid tert-Butyl Ester
  • tert-Butyl 2-((4R,6R)-6-(cyanoMethyl)-2,2-diMethyl-1,3-dioxan-4-yl)acetate
  • 1,3-Dioxane-4-aceticacid, 6-(cyanoMethyl)-2,2-diMethyl-, 1,1-diMethylethyl ester, (4R,6R)-
  • tert-Butyl (4R,6R)-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate 97%
  • <i>tert</i>-Butyl (4<i>R</i>,6<i>R</i>)-6-Cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
  • Atorvastatin intermediatesAts-8
  • (4R-Cis)-l,l-Dimethylethyl-6-Cyanomethyl-2,2-Dimethyl-1,3-Dioxane-4-Aceta
  • Atorvastatin Impurity 7
  • Atorvastatin Acetonide t-Butyl Ester Side Chain (4R,6R)-Isomer
  • 4R CIS)-1.1-DIMETHYLETHYL-6-CYANOMETHYL- 2 2-DIMETHYL-1 3-DIOXANE-4-ACETAT
  • Atorvastatin Impurity 63
  • 2-[6-(bromomethyl)-1,3-dioxan-4-yl]-3,3-dimethylbutanoate
  • Atorvastatin Calcium Hydrate impurity 19
  • Atorvastatin calcium-11
  • Ats-8:(4R,Cis)-1,1-Dimethylethyl-Cyanomethyl-2,2-Dimethyl
  • (4R)-cis-6-1,1-Dimethyl-6-cyanomethyl-2-2-dimethyl-1,3-dioaneacetate
  • Intermediateofatorvastatinecalcium(CAS#134523-03-8)
  • 1,3-Dioxane-4-acetic acid, 6-(cyanomethyl)-2,2-dimethyl-1,1-dimethylethylester
  • TERT-BUTYL[(4R,6R)-6-CYANOMETHYL-1,3-DIOXAN-4-YL]ACETATE
  • (4R,6R)-t-Butyl-6-AMINOMETHYL-2,2-dimethyl-1,3-dioxane-4-acetate
  • (4R,6R)-Tert-Butyl-6-Cyanometh
  • ATS 8 (4R,CIS)-1,1-DIMETHYLETHY-L-CYANOMETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE
  • ATS-8:(4R-CIS)-T-ETHYL-6-CYANOMETHYL-2,2-DIMETHYL-1,2-DIMETHYL-1,2-DIONMANO 1 ACETATE
  • (4R-Cis)-1,1-dimethylethyl-6-cyanomethyl-2,2-dimethyl-1,3-dio-cxane-4-acetate
  • (4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate,97%
  • Tert-Butyl(3R,5R)-6-cyano-3,5-O-iso-propylidene-3,5-dihydroxyhexanoate
  • (4R,6R)-tert-Butyl-6
  • (4R-Cis)-1,1-diMethylethyl-6-Cyanoethyl-2,2-diMethyl-1,3-dioxane-4-acetate
  • ATS-8 (4R, cis)C1,1-dimethylethyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane C4-Acetate
  • Tetr-butyl[(4R,6R)-6-cyanomethyl-1,3-dioxan-4-yl]acetate
  • tert-Butyl 6-cyanomethyl-2,2-dimethyl-1,3-dioxolane-4-acetate
  • tert-Butyl (4R,6R)-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
  • 2-[6-(cyanoMethyl)-2,2-diMethyl-1,3-dioxan-4-yl]-3,3-diMethylbutanoate
  • Ats-8(For Atorvastatin)
  • ((4R,6R)-6-(Cyanomethyl)-2,2-dimethyl-[1,3]dioxan-4-yl)acetic acid tert-butyl ester
  • tert-Butyl(4R,6R)-6-Cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate&gt
  • (4R,6R)-1,3-Dioxane-4-acetic acid, 6-(cyanomethyl)-2,2-dimethyl-, 1,1-dimethylethyl ester
  • (4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane- 4-acetate(A8)
  • (4R-cis)-6-1,1-Dimethyl-6-cyanomethly-2-2-dimethly-1,3-dioane-acetate
  • (4r-Cis)-1,1-Dimethylethyl-6-Cyanomethyl-2,2-Dimethyl-1,3-Di...
  • 1,1-Dimethylethyl 2-[(4R,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate
  • tert-Butyl 2-((4R,6R)-6-cyanomethyl-2,2- dimethyl-1,3-dioxane-4-yl)acetate
  • 1,1-Dimethylethyl (4R,6R)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetate
  • (4r,6r)-tert-butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate (ATS-8)
  • Atorvastatin calcium impurity 19
  • (4R,Cis)-1,1-dimethylethyl-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate (ATS-8)
  • ATS-8（Intermediate of Atorvastatin)
  • 125971-94-0