ChemicalBook > CAS DataBase List > (4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate

(4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate

Product Name
(4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate
CAS No.
125995-13-3
Chemical Name
(4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate
Synonyms
ATS-9;(4R,6R)-T-BUTYL-6-(2-AMINOETHYL)-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE;2-diMethyl-1;Atorvastatin A9;3-dioxane-4-acetate;Atorvastatin Impurity Ⅱ;Atorvastatin calcium-10;Atorvastatin Impurity 83;Atarvostatin intermediate;ATROVASTATIN INTERMEDIATES
CBNumber
CB2218182
Molecular Formula
C14H27NO4
Formula Weight
273.37
MOL File
125995-13-3.mol
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(4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate Property

Boiling point:
339.8±17.0 °C(Predicted)
Density 
0.992±0.06 g/cm3(Predicted)
refractive index 
1.454-1.456
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
soluble in Chloroform
pka
9.80±0.10(Predicted)
form 
Viscous Liquid
color 
Light yellow to green or light blue
λmax
204nm(EtOH)(lit.)
InChIKey
HWSHVKNLMBMKSR-GHMZBOCLSA-N
CAS DataBase Reference
125995-13-3(CAS DataBase Reference)
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Safety

Safety Statements 
24/25
HS Code 
29153900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical
Product number
B3702
Product name
tert-Butyl 2-[(4R,6R)-6-(2-Aminoethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate
Purity
>98.0%(GC)
Packaging
1g
Price
$32
Updated
2024/03/01
TCI Chemical
Product number
B3702
Product name
tert-Butyl 2-[(4R,6R)-6-(2-Aminoethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate
Purity
>98.0%(GC)
Packaging
5g
Price
$96
Updated
2024/03/01
TRC
Product number
C497250
Product name
(4R,cis)-1,1-Dimethylethyl-6-aminoethyl-2,2-dimethyl-1,3-dioxane-4-acetate
Packaging
50mg
Price
$65
Updated
2021/12/16
Matrix Scientific
Product number
072506
Product name
(4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate
Purity
95+%
Packaging
25g
Price
$192
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
JK252048
Product name
(4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate
Packaging
1g
Price
$102
Updated
2021/12/16
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(4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate Chemical Properties,Usage,Production

Description

(4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate is an impurity of Atorvastatin. Atorvastatin is a drug used to lower cholesterol levels in the blood. It belongs to a class of drugs called HMG-CoA reductase inhibitors, and it works by blocking an enzyme that plays a role in the production of cholesterol.

Chemical Properties

Colorless to light yellow liqui

Uses

(4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate is an useful synthetic intermediate.

Uses

An impurity of Atorvastatin (A791750).

(4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate Preparation Products And Raw materials

Raw materials

Preparation Products

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(4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate Suppliers

Americas 1 Australia 1 Belgium 1 Canada 6 China 225 Europe 3 Germany 4 India 41 Japan 3 Poland 1 Spain 1 Switzerland 1 United Kingdom 12 United States 61 Global 361
Shanghai Qianhe Biological Technology Co., Ltd.
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021-58337595 13621714589
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93732879@qq.com
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China
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J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
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86-10-82849933
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jkinfo@jkchemical.com
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China
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Energy Chemical
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Capot Chemical Co., Ltd
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+86 (0) 571 85 58 67 18
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0086-571-85864795
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JinYan Chemicals(ShangHai) Co.,Ltd.
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13817811078
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View Lastest Price from (4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate manufacturers

hebei hongtan Biotechnology Co., Ltd
Product
(4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate 125995-13-3
Price
US $30.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
3000kg
Release date
2024-03-22
Henan Fengda Chemical Co., Ltd
Product
(4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate 125995-13-3
Price
US $8.00-0.80/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-01-22
R&D Scientific Inc.
Product
(4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate 125995-13-3
Price
US $850.00/Kg
Min. Order
1Kg
Purity
98
Supply Ability
500 Kg
Release date
2024-02-21

125995-13-3, (4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetateRelated Search:

tert-Butyl peroxyacetate tert-Butyl chloroacetate Methyl 2,2-dimethylphenylacetate tert-Butyl acetate Butyl acetate Dacthal N,N-Dimethylformamide tert-Butyl bromoacetate Dimethyl carbonate tert-Butanol Isobutyl acetate ETHANE Dimethyl fumarate Dimethylbenzylcarbinyl acetate Dimethyl ether Dimethyl phthalate Dimethyl sulfate Dimethyl disulfide

  • (4R,CIS)-1,1-DIMETHYLETHYL-6-AMINOETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE
  • (4R-Cis)-1,1-Dimethylethyl-6-aminoethyl-2,2-dimethyl-1,3-dioxoane-4-acetate
  • (4R,6R)-T-BUTYL-6-(2-AMINOETHYL)-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE
  • (4R,6R)-TERT-BUTYL-6-(2-AMINOETHYL)-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE
  • ATS-9
  • (4R-CIS)-1,1-DIMETHYLETHYL-6-AMINOETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE (ATS-9)
  • Atorvastatin Intermediate Ⅰ
  • Atorvastatin Intermediate 1
  • ATROVASTATIN INTERMEDIATES
  • (4R-Cia)-1,1-dimethyl ethyl-6-cyano methyl-2,2-dimethyl-1,3-dioxane-4-acetate
  • (4R,Cis)-1,1-Dimethylethyl-6-(2-Aminoethyl)-2,2-Dimethyl-1,3-Dioxane-4-Acetate
  • (4R-cis)-1,1-dimethylethyl-6-aminoethyl- 2,2-dimethyl-1,3-dloxane-4-acetate
  • (4R,6R)-6-(2-aminoethyl)-2,2-dimethyl-1,3-Dioxane-4-acetic acid, 1,1-dimethylethyl ester
  • TERT-BUTYL[(4R,6R)-6-(2-AMINOETHYL)-2,2-DIMETHYL-1, 3-DIOXAN-4-YL]ACETATE
  • ATS-9 (4R, cis)C1,1-dimethylethyl-6-aminoethyl-2,2-dimethyl-1,3-dioxane C4-Acetate
  • (4R, 6R)-6-(2aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetic acid tert-Butyl Ester
  • <i>tert</i>-Butyl 2-[(4<i>R</i>,6<i>R</i>)-6-(2-Aminoethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate
  • (4R, 6R)-6-(2aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetic acid tert-Butyl Easter
  • (4R,6R)-Tert-Butyl-6-(2-Aminoe
  • ATS 9 (4R,CIS)-1,1-DIMETHYLETHYL-6-AMINOETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE
  • TERT-BUTYL 2-((4R,6S)-6-(AMINOMETHYL)-2,2-DIMETHYL-1,3-DIOXAN-4-YL)ACETATE
  • (4R-Cis)-1,1-dimethylethyl-6-aminomethyl-2,2-dimethyl-1,3-dio-cxane-acetate
  • Atorvastatin Impurity Ⅱ
  • Atorvastatin intermediatesAts-9
  • Atorvastatin calcium-10
  • Atorvastatin Impurity 83
  • tert-butyl [(4R,6R)-6-aminoethyl-2,2-dimethyl-1,3-dioxan-4-yl]acetate
  • tert-Butyl 6-aminoethyl-2,2-dimethyl-1,3-dioxolane-4-acetate
  • (4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate,95%
  • 2-diMethyl-1
  • 3-dioxane-4-acetate
  • 6R)-tert-Butyl-6-(2-aMinoethyl)-2
  • (4<i>R</i>,6<i>R</i>)-<i>tert</i>-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate
  • 1,3-Dioxane-4-acetic acid, 6-(2-aminoethyl)-2,2-dimethyl-, 1,1-dimethylethyl ester, (4R,6R)-
  • 4R,6R)-tert-Butyl-6-(2-aMinoethyl)-2,2-diMethyl-1
  • (4R,Cis)-1,1-diMethylethyl6-aMinoethyl
  • 2-[(4R,6R)-6-(2-Aminoethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetic Acid tert-Butyl Ester
  • 2-[6-(2-AMinoethyl)-2,2-diMethyl-1,3-dioxan-4-yl]-3,3-diMethylbutanoate
  • 1,1-Dimethylethyl (4R-cis)-6-Aminoe
  • tert-Butyl 2-[(4R,6R)-6-(2-Aminoethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate &gt
  • (4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3- dioxane-4-acetate（A9）
  • ATORVASTATIN A9 (4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate
  • (4R,6R)-t-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-...
  • 2-[(4R,6R)-2,2-dimethyl-6-[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]-1,3-dioxan-4-yl]ethylazanium
  • Atorvastatin Intermediate A9
  • 1,1-Dimethylethyl (4R-cis)-6-Aminoethyl-2,2-dimethyl-1,3-dio
  • tert-Butyl 2-((4R,6R)-6-aminoethyl-2,2- dimethyl-1,3-dioxane-4-yl)acetate
  • 1,1-Dimethylethyl (4R,6R)-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate
  • Atorvastatin calcium impurity 18
  • Atarvostatin intermediate
  • tert-Butyl 2-[(4R,6R)-6-(2-Aminoethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate, ≥ 98.0%
  • Atorvastatin A9
  • 125995-13-3
  • C14H28NO4
  • C14H27NO4
  • Amines
  • Chiral Reagents
  • Inhibitors