N3-PEG8-CH2COOH

Product Name: N3-PEG8-CH2COOH
CAS No.: 1343472-07-0
Chemical Name: N3-PEG8-CH2COOH
Synonyms: N3-PEG8-CH2COOH;N3-PEG8-CH2CO2H;Azido-PEG8-CH2CO2H;AZIDE-PEG8-CH2COOH;26-Azido-3,6,9,12,15,18,21,24-octaoxahexacosanoic acid;N3-PEG8-CH2COOH/3,6,9,12,15,18,21,24-Octaoxahexacosanoic acid, 26-azido-
CBNumber: CB63340576
Molecular Formula: C18H35N3O10
Formula Weight: 453.49
MOL File: 1343472-07-0.mol

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N3-PEG8-CH2COOH Property

storage temp.: Store at Room Tem.

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Usbiological

Product number: 285408
Product name: N3-PEG8-CH2COOH
Packaging: 250mg
Price: $914
Updated: 2021/12/16

Activate Scientific

Product number: AS104031
Product name: N3-PEG8-CH2COOH
Purity: 95+%
Packaging: 1g
Price: $730
Updated: 2021/12/16

Acrotein

Product number: B-0902
Product name: N3-PEG8-CH2COOH
Purity: 97%
Packaging: 0.25g
Price: $256.66
Updated: 2021/12/16

purepeg

Product number: 437508
Product name: N3-PEG8-CH2COOH
Purity: min.97%
Packaging: 250mg
Price: $275
Updated: 2021/12/16

purepeg

Product number: 437508
Product name: N3-PEG8-CH2COOH
Purity: min.97%
Packaging: 1g
Price: $550
Updated: 2021/12/16

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N3-PEG8-CH2COOH Chemical Properties,Usage,Production

Description

Azido-PEG8-CH2CO2H is a aqueous soluble PEG linker. The hydrophilic PEG spacer increases solubility in aqueous media. Azide (N3) group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Uses

N3-PEG8-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. N3-PEG8-CH2COOH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs

References

[1] Steinmetz NF, et al. Intravital imaging of human prostate cancer using viral nanoparticles targeted to gastrin-releasing Peptide receptors. Small. 2011 Jun 20;7(12):1664-72. DOI:10.1002/smll.201000435

N3-PEG8-CH2COOH Preparation Products And Raw materials

Raw materials

Preparation Products

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N3-PEG8-CH2COOH Suppliers

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1343472-07-0, N3-PEG8-CH2COOHRelated Search:

Azido-PEG5-CH2CO2-PFP N3-PEG5-CH2COOH Azido-PEG8-CH2CO2-PFP

N3-PEG8-CH2COOH

AZIDE-PEG8-CH2COOH

Azido-PEG8-CH2CO2H

N3-PEG8-CH2CO2H

N3-PEG8-CH2COOH/3,6,9,12,15,18,21,24-Octaoxahexacosanoic acid, 26-azido-

26-Azido-3,6,9,12,15,18,21,24-octaoxahexacosanoic acid

1343472-07-0

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