CATHARANTHINE TARTRATE

Product Name: CATHARANTHINE TARTRATE
CAS No.: 4168-17-6
Chemical Name: CATHARANTHINE TARTRATE
Synonyms: LFP 754;LFP-754;Levofolene;levo-Folinic;Levofolinic acid;CATHARANTHINE TARTRATE;Catharanthine hemitartrate;CATHARANTHINE TARTRATE USP/EP/BP;Catharanthine tartrate, 10 mM in DMSO;2648-21-5，2648-21-5，Catharanthine Tartrate
CBNumber: CB6336510
Molecular Formula: C25H30N2O8
Formula Weight: 486.51
MOL File: Mol file

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CATHARANTHINE TARTRATE Property

Melting point:: 145-1470C
storage temp.: Inert atmosphere,2-8°C
solubility: DMSO (Slightly), Ethyl Acetate (Slightly, Heated), Methanol (Slightly, Heated)
form: White to off-white crystalline powder.
color: White to Pale Beige
InChIKey: JYBKPXVXYJDIFX-GYMDHWDQSA-N
SMILES: [C@]12(C(OC)=O)[C@]3(C(=C[C@]([H])(CN3CCC3C4=C(C=CC=C4)NC1=3)C2)CC)[H].C(O)(C(O)=O)C(O)C(O)=O

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: L204161
Product name: METHYL 3,4-DIDEHYDROIBOGAMINE-18-CARBOXYLATE 2,3-DIHYDROXYSUCCINATE (2:1)
Purity: Aldrich<sup>CPR</sup>
Packaging: 1 unit
Price: $152
Updated: 2026/03/19

Sigma-Aldrich

Product number: L204161
Product name: METHYL 3,4-DIDEHYDROIBOGAMINE-18-CARBOXYLATE 2,3-DIHYDROXYSUCCINATE (2:1)
Purity: AldrichCPR
Packaging: 10MG
Price: $139
Updated: 2024/03/01

Cayman Chemical

Product number: 11695
Product name: Catharanthine (tartrate)
Purity: ≥98%
Packaging: 50 mg
Price: $38
Updated: 2024/03/01

Cayman Chemical

Product number: 11695
Product name: Catharanthine (tartrate)
Purity: ≥98%
Packaging: 100 mg
Price: $71
Updated: 2024/03/01

Cayman Chemical

Product number: 11695
Product name: Catharanthine (tartrate)
Purity: ≥98%
Packaging: 500 mg
Price: $330
Updated: 2024/03/01

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CATHARANTHINE TARTRATE Chemical Properties,Usage,Production

Chemical Properties

Off-White to Pale Beige Solid

Uses

Precursor of Vinblastine-type alkaloids.

Synthesis

Using fresh whole Catharanthus roseus plant:
1) Soaking in NaCl solution, freeze-drying, and pulverizing.
2) Acidic extraction, basification, and counter-current extraction using a spray method with an extractant (n-bromopropane/ethanol).
3) Work-up of the organic phase and acidification.
4) Multiple extraction and pH adjustment steps yield crude catharanthine.
5) The crude base is salified with tartaric acid and recrystallized to obtain pure catharanthine tartrate.

in vivo

Catharanthine ((+)-3,4-Didehydrocoronaridine; 0.5-20 mg/kg; IV; single dose) Tartrate evokes dose-dependent reductions in both BP and HR^[1].
Catharanthine (40 mg/kg; ip; single dose) Tartrate with acute administration induces similar antidepressant-like activity in male and female mice at 1 h and 24 h^[1].
Catharanthine (20 mg/kg; ip; for 14 consecutive days) Tartrate increases swimming time and decreases immobility time at D7 or D14 in mice^[1].

Animal Model:	13-week-old male SpragueDawley rats (300-350 g)^[1]
Dosage:	0.5-20 mg/kg
Administration:	IV; single dose
Result:	Evoked rapid, transient reductions in BP and HR (lasting ,2 minutes) at low doses (0.5–5 mg/kg), whereas at higher doses (10 and 20 mg/kg), the BP and HR reductions were sustained.

IC 50

L-type calcium channel

CATHARANTHINE TARTRATE Preparation Products And Raw materials

Raw materials

Preparation Products

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CATHARANTHINE TARTRATE Suppliers

Canada 1 China 139 Europe 2 India 3 Switzerland 1 United Kingdom 2 United States 17 Global 165

Nanjing Bencao Yikang Biotechnology Co., Ltd

Tel: 025-69790911 18362932668
Email: 522593521@qq.com
Country: China
ProdList: 1163
Advantage: 58

Chengdu Peter-like Biotechnology Co., Ltd.

Tel: 028-81700200 13308200041
Email: 2851167782@qq.com
Country: China
ProdList: 10940
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Chembest Research Laboratories Limited

Tel: 021-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6003
Advantage: 61

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Beijing Zhongshuo Pharmaceutical Technology Development Co., Ltd

Tel: 13801208576
Fax: 010-64215766
Email: maggie@chinazhongshuo.com
Country: China
ProdList: 101
Advantage: 65

BOC Sciences

Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 12952
Advantage: 65

Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: sales@meilune.com
Country: China
ProdList: 4790
Advantage: 58

Shanghai Tauto Biotech Co., Ltd.

Tel: 021-51320588
Fax: 0086-21-51320502
Email: tauto@tautobiotech.com
Country: China
ProdList: 3988
Advantage: 66

Guangzhou Isun Pharmaceutical Co., Ltd

Tel: 020-39119399 18927568969
Fax: 020-39119999
Email: isunpharm@qq.com
Country: China
ProdList: 4769
Advantage: 55

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View Lastest Price from CATHARANTHINE TARTRATE manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: Catharanthine Tartrate 4168-17-6
Price: US $3.00-9.00/KG
Min. Order: 0.1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2025-06-27

Shanghai Standard Technology Co., Ltd.

Product: Catharanthine hemitartrate 4168-17-6
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2020-03-10

Dideu Industries Group Limited

Product: CATHARANTHINE TARTRATE 4168-17-6
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons Min
Release date: 2021-06-30

4168-17-6, CATHARANTHINE TARTRATERelated Search:

CATHARANTHINE SULFATE Vinblastine sulfate Vinorelbine Vincamine LEUROSINE VINBLASTINE Vincristine DESACETYLVINBLASTINEAMIDE D(-)-Tartaric acid Vinorelbine tartrate Coated choline tartrate Basic copper tartrate Choline Bitartrate Choline bitartrate Catharanthine

CATHARANTHINE TARTRATE

7-ETHYL-9,10,12,13-TETRAHYDRO-6,9-METHANO-5H-PYRIDO[1',2':1,2]AZEPINO[4,5-B]INDOLE-6(6AH)-CARBOXYLIC ACID METHYL ESTER TARTRATE

(2alpha,5beta,6alpha,18beta)-3,4-Didehydroibogamine-18-carboxylic acid methyl ester (2R,3R)-2,3-dihydroxybutanedioate

Catharanthine hemitartrate

(2α,5β,6α,18β)-3,4-Didehydro-ibogaMine-18-carboxylic Acid Methyl Ester Tartrate

Bis[(5ξ,18ξ)-18-(methoxycarbonyl)-3,4-didehydroibogamin-6-ium] tartarate

CATHARANTHINE TARTRATE USP/EP/BP

Levofolene

levo-Folinic

Levofolinic acid

LFP 754

LFP-754

Catharanthine tartrate, 10 mM in DMSO

METHYL 3,4-DIDEHYDROIBOGAMINE-18-CARBOXYLATE 2,3-DIHYDROXYSUCCINATE (2:1)

Methyl (6R,6aR,9R)-7-ethyl-9,10,12,13-tetrahydro-5H-6,9-methanopyrido[1',2':1,2]azepino[4,5-b]indole-6(6aH)-carboxylate hemi((2R,3R)-2,3-dihydroxysuccinate)

2648-21-5，2648-21-5，Catharanthine Tartrate

4168-17-6

2648-21-5

C21H24N2O2C4H6O6

2C21H24N2O2C4H6O6

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract

Anti-cancer & immunity

Inhibitors

Chiral Reagents

Heterocycles

Intermediates & Fine Chemicals

Pharmaceuticals