(3-Nitrobenzyl)methylamine
- Product Name
- (3-Nitrobenzyl)methylamine
- CAS No.
- 19499-61-7
- Chemical Name
- (3-Nitrobenzyl)methylamine
- Synonyms
- N-Methyl-1-(3-nitrophenyl)MethanaMine;(3-Nitrobenzyl)methy;(3-NITROBENZYL)METHYLAMINE;3-Nitro-N-methylbenzylamine;N-Methyl-3-nitrobenzylamine;(3-NITROBENZYL)METHYLAMINE 95%;N-METHYL-N-(3-NITROBENZYL)AMINE;N-Methyl-3-nitrobenzylamine,95%;(3-Nitrobenzyl)MethylaMine, 98%+;N-Methyl-3-nitrobenzylaMine, 95%
- CBNumber
- CB6339788
- Molecular Formula
- C8H10N2O2
- Formula Weight
- 166.18
- MOL File
- 19499-61-7.mol
(3-Nitrobenzyl)methylamine Property
- Melting point:
- 160 °C
- Boiling point:
- 128 °C
- Density
- 1.162±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 8.94±0.10(Predicted)
- form
- Oil
- Appearance
- Light brown to brown Liquid
- Water Solubility
- Slightly soluble in water.
- InChI
- InChI=1S/C8H10N2O2/c1-9-6-7-3-2-4-8(5-7)10(11)12/h2-5,9H,6H2,1H3
- InChIKey
- NTPAPKLGADEFAM-UHFFFAOYSA-N
- SMILES
- C1(CNC)=CC=CC([N+]([O-])=O)=C1
Safety
- HazardClass
- 8
- HS Code
- 2921490090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H314Causes severe skin burns and eye damage
H318Causes serious eye damage
- Precautionary statements
-
P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- N926365
- Product name
- (3-Nitrobenzyl)methylamine
- Packaging
- 500mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- W4161
- Product name
- (3-Nitrobenzyl)methylamine
- Packaging
- 5g
- Price
- $114
- Updated
- 2021/12/16
- Product number
- OR913010
- Product name
- N-Methyl-N-(3-nitrobenzyl)amine
- Purity
- 98%
- Packaging
- 10g
- Price
- $182
- Updated
- 2021/12/16
- Product number
- 071763
- Product name
- (3-Nitrobenzyl)methylamine
- Purity
- 95+%
- Packaging
- 5g
- Price
- $200
- Updated
- 2021/12/16
- Product number
- 071763
- Product name
- (3-Nitrobenzyl)methylamine
- Purity
- 95+%
- Packaging
- 1g
- Price
- $70
- Updated
- 2021/12/16
(3-Nitrobenzyl)methylamine Chemical Properties,Usage,Production
Uses
N-Methyl-3-nitrobenzylamine is employed as a important raw material and intermediate used in organic synthesis agrochemical, pharmaceutical and dyestuff field.
Synthesis
99-61-6
74-89-5
19499-61-7
1. m-Nitrobenzaldehyde (1 eq., 13.2 mmol, 2.0 g), 40% aqueous methylamine (1.1 eq., 14.5 mmol, 0.95 mL), and 3A molecular sieves (100 mg) were sequentially added to a screw-capped through-hole reaction vial. 2. The reaction mixture was heated at 80 °C for 24 hours. 3. After completion of the reaction, it was cooled to room temperature, the reaction mixture was diluted with chloroform (3 mL) and filtered to remove the molecular sieves. 4. The solvent was removed by rotary evaporation to obtain the crude product. The crude product was dissolved in methanol (30 mL) and cooled to 0°C. 5. Sodium borohydride (1.1 equiv, 14.5 mmol, 550 mg) was added in three batches and the reaction mixture was gradually warmed to room temperature and the reaction was continued for 24 hours. 6. Upon completion of the reaction, the reaction was quenched with 5% aqueous ammonium hydroxide (10 mL) and the solvent was removed by concentration by rotary evaporation. 7. The resulting aqueous layer was extracted with dichloromethane (3 x 10 mL) and the organic phases were combined. 8. The organic phase was dried with anhydrous sodium sulfate, filtered and the filtrate was concentrated by rotary evaporation. 9. The residue was purified by rapid chromatography on silica gel or distilled under vacuum to obtain the target product N-methyl-3-nitrobenzylamine.
References
[1] Molecules, 2017, vol. 22, # 12,
[2] Patent: WO2013/140347, 2013, A1. Location in patent: Page/Page column 48-49
[3] Patent: US2015/51257, 2015, A1. Location in patent: Paragraph 0519-0520
(3-Nitrobenzyl)methylamine Preparation Products And Raw materials
Raw materials
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View Lastest Price from (3-Nitrobenzyl)methylamine manufacturers
- Product
- (3-Nitrobenzyl)methylamine 19499-61-7
- Price
- US $100.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-26
- Product
- (3-Nitrobenzyl)methylamine 19499-61-7
- Price
- US $0.00-0.00/Kg
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 100 tons
- Release date
- 2020-01-10