ChemicalBook > CAS DataBase List > H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-OH

H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-OH

Product Name
H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-OH
CAS No.
109770-29-8
Chemical Name
H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-OH
Synonyms
SP28;Fam-β-Amyloid;β-Amyloid (1-28);Amyloid beta(1-28);BETA-AMYLOID (1-28);AMyloid b-Protein (1-28);Amyloid β-Protein (1-28);AMYLOID BETA-PROTEIN (1-28);beta-Amyloid Peptide (1-28);DAEFRHDSGYEVHHQKLVFFAEDVGSNK
CBNumber
CB6344029
Molecular Formula
C145H209N41O46
Formula Weight
3262.46
MOL File
109770-29-8.mol
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H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-OH Property

Density 
1.52±0.1 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
Soluble in DMSO
form 
White lyophilized powder.
Sequence
H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-OH
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0044400
Product name
β-Amyloid(1-28)
Packaging
1mg
Price
$110
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA110260
Product name
Amyloid beta-Protein (1-28) trifluoroacetate salt
Packaging
1mg
Price
$136
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA110260
Product name
Amyloid beta-Protein (1-28) trifluoroacetate salt
Packaging
2mg
Price
$231
Updated
2021/12/16
ChemScene
Product number
CS-0044400
Product name
β-Amyloid(1-28)
Packaging
5mg
Price
$440
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA110260
Product name
Amyloid beta-Protein (1-28) trifluoroacetate salt
Packaging
5mg
Price
$462
Updated
2021/12/16
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H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-OH Chemical Properties,Usage,Production

Uses

β-Amyloid (1-28) is a β-Amyloid protein fragment involved in metal binding. Beta-amyloid is a peptide that forms amyloid plaques in the brains of Alzheimer's disease (AD) patients.

in vivo

β-Amyloid (1-28) fragment is considered as valid models to examine the contribution of the key histidine residues (His , His in mouse and His , His , His in human fragments) to the Ab–Cu2+ interaction[1]. Copper binds to β-Amyloid (1-28) at pH 7.4 with an affinity of Ka10 7 M-1[2].

References

[1] Kowalik-Jankowska T, et al. Coordination abilities of the 1-16 and 1-28 fragments of beta-amyloid peptide towards copper(II) ions: a combined potentiometric and spectroscopic study. J Inorg Biochem. 2003 Jul 1;95(4):270-82. DOI:10.1016/s0162-0134(03)00128-4
[2] Syme CD, et al. Copper binding to the amyloid-beta (Abeta) peptide associated with Alzheimer's disease: folding, coordination geometry, pH dependence, stoichiometry, and affinity of Abeta-(1-28): insights from a range of complementary spectroscopic techni DOI:10.1074/jbc.M313572200
[3] Jing-Ming Shi, et al. Dissecting the behaviour of β-amyloid peptide variants during oligomerization and fibrillation. J Pept Sci. 2017 Nov;23(11):810-817. DOI:10.1002/psc.3028

H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-OH manufacturers

Zibo Hangyu Biotechnology Development Co., Ltd
Product
Beta-Amyloid (1-28) 109770-29-8
Price
US $0.10-0.30/kg
Min. Order
1kg
Purity
≥98.0%
Supply Ability
20 tons
Release date
2024-01-06
Zibo Hangyu Biotechnology Development Co., Ltd
Product
[Gln11] -Bate- Amyloid (1 - 28) 109770-29-8
Price
US $0.10-0.30/kg
Min. Order
1kg
Purity
95%、98%
Supply Ability
20 tons
Release date
2024-01-08
GenicBio Limited
Product
Beta-Amyloid (1-28) 109770-29-8
Price
US $1.00/MG
Min. Order
5MG
Purity
>95%
Supply Ability
5mg,10mg,25mg,100mg,1g,10g
Release date
2018-07-28

109770-29-8, H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-OHRelated Search:

Amyloid β-Protein (1-42) (mouse, rat) Amyloid β-Peptide (1-42) (human) H-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-OH PEPTIDE WITH REVERSED SEQUENCE OF AMYLOID BETA-PROTEIN (HUMAN, 1-40) TRIFLUOROACETATE H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-OH Amyloid β-Protein (3-40) Amyloid Beta-Protein (1-14) AMYLOID BETA-PROTEIN (HUMAN, 25-35) TRIFLUOROACETATE Amyloid β-Protein (4-42) H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-OH H-MET-LEU-GLY-ILE-ILE-ALA-GLY-LYS-ASN-SER-GLY-OH BETA-AMYLOID (1-43) Amyloid β-Protein (1-6) H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET-VAL-GLY-GLY-VAL-VAL-ILE-ALA-THR-VAL-ILE-VAL-OH AMYLOID BETA-PROTEIN (1-40) (MOUSE, RAT) Amyloid β-Protein (1-12) AMYLOID BETA-PROTEIN (29-40) H-GLU-ASP-VAL-GLY-SER-ASN-LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET-OH

  • SP28
  • DAEFRHDSGYEVHHQKLVFFAEDVGSNK
  • H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-OH
  • ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS
  • BETA-AMYLOID PEPTIDE [1-28], HUMAN
  • BETA-AMYLOID (1-28), N-TERMINAL UNLABELED
  • BETA-AMYLOID (1-28)
  • amyloid B-protein fragment 1-28
  • B-AMYLOID PROTEIN (1-28) >97% SYNTHETIC
  • ALZHEIMER'S DISEASE BETA-PROTEIN (SP28)
  • ALZHEIMER'S DISEASE PROTEIN [1-28]
  • AMYLOID BETA-PROTEIN (HUMAN, 1-40) TRIFLUOROACETATE
  • AMYLOID BETA-PROTEIN (HUMAN, 1-43) TRIFLUOROACETATE
  • AMYLOID BETA-PROTEIN FRAGMENT 1-28
  • AMYLOID, BETA- (1-28), HUMAN
  • AMYLOID BETA-PROTEIN (1-28)
  • AMYLOID-BETA PROTEIN (1-28), HUMAN
  • AMyloid β-Protein (1-28) AlzheiMer's Disease β-Protein (SP28)
  • AlzheiMer's Disease b-Protein (SP28)
  • AMyloid b-Protein (1-28)
  • Fam-β-Amyloid
  • Amyloid beta-Protein (1-28) trifluoroacetate salt
  • L-Lysine, L-α-aspartyl-L-alanyl-L-α-glutamyl-L-phenylalanyl-L-arginyl-L-histidyl-L-α-aspartyl-L-serylglycyl-L-tyrosyl-L-α-glutamyl-L-valyl-L-histidyl-L-histidyl-L-glutaminyl-L-lysyl-L-leucyl-L-valyl-L-phenylalanyl-L-phenylalanyl-L-alanyl-L-α-glutamyl-L-α-aspartyl-L-valylglycyl-L-seryl-L-asparaginyl-
  • [Gln11] -β- Amyloid (1 - 28)
  • β-Amyloid (1-28)
  • Amyloidβ-Protein(1-28),β-Amyloid(1-28)
  • Human β-amyloid peptide(1-28)
  • H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-OH USP/EP/BP
  • Amyloid β-Protein (1-28)
  • AMyloid β-Protein (1-28) AlzheiMer's Disease β-Protein (SP28)
  • Alzheimer's Disease β-Protein (SP28)
  • Amyloid β-Protein (1-28) trifluoroacetate salt
  • β-Amyloid (1-28)|beta-Amyloid (1-28)
  • Amyloid beta(1-28)
  • [Gln11] -Bate- Amyloid (1 - 28)
  • beta-Amyloid Peptide (1-28)
  • Amyloid β-Protein (Human, 1-28) (0.5 mg vial)
  • Amyloid β-Protein (1-28)、Aβ1-28
  • 109770-29-8
  • Biochemicals and Reagents
  • Amino Acids and Peptides
  • Amyloid beta Protein Fragments
  • BioChemical
  • Peptides
  • Neurodegenerative Disease Peptides
  • peptide