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4-Bromomethyl-7-methoxycoumarin

Product Name
4-Bromomethyl-7-methoxycoumarin
CAS No.
35231-44-8
Chemical Name
4-Bromomethyl-7-methoxycoumarin
Synonyms
BMC;BR-MMC;BMC, Br-Mmc;-7-methoxy-2H-chromen-2-one;4-BROMOETHYL-7-METHOXYCOUMARIN;4-Bromomethyl-7-methoxycoumain;4-bromomethyl-7-hydroxycoumarin;7-Methoxy-4-bromomethylcoumarin;4-BROMOMETHYL-7-METHOXYCOUMARIN;4-BroMoMethyl-7-MethoxycouMarine
CBNumber
CB6345309
Molecular Formula
C11H9BrO3
Formula Weight
269.09
MOL File
35231-44-8.mol
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4-Bromomethyl-7-methoxycoumarin Property

Melting point:
213-215 °C (lit.)
Boiling point:
385.3±42.0 °C(Predicted)
Density 
1.552±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
solubility 
chloroform: soluble20mg/mL, clear, colorless to faintly yellow
form 
Powder and/or Chunks
color 
Off-white to light yellow or beige
Water Solubility 
insoluble
λmax
330 nm (MeOH)
BRN 
187211
Stability:
Stable, but moisture and light-sensitive. Combustible. Incompatible with strong oxidizing agents.
Major Application
Detection of nitrated explosives; measuring ultraviolet ray power; photoacid generators; polyurethane foams; photoresists silica nanoparticles
Biological Applications
Analyzing/detecting carboxylic acids;analyzing/labeling fatty acids; detecting nitric oxide; detecting/separating bile acids; labeling pyrimidine nucleobases; anticancer agents; biomedical trace analysis; herbicides; as a substrate for measuring histone acetyltransferases (HATs) activity, peptidases activity, sirtuin activity
LogP
2.730 (est)
CAS DataBase Reference
35231-44-8(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-22
Safety Statements 
26-36-37/39
RIDADR 
1759
WGK Germany 
3
HazardClass 
8
PackingGroup 
III
HS Code 
29322090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
235202
Product name
4-Bromomethyl-7-methoxycoumarin
Purity
97%
Packaging
1g
Price
$65.4
Updated
2024/03/01
Sigma-Aldrich
Product number
235202
Product name
4-Bromomethyl-7-methoxycoumarin
Purity
97%
Packaging
5g
Price
$248
Updated
2024/03/01
TCI Chemical
Product number
A5551
Product name
Br-Mmc (=4-Bromomethyl-7-methoxycoumarin)[for HPLC Labeling]
Purity
>98.0%(T)
Packaging
1g
Price
$91
Updated
2024/03/01
TCI Chemical
Product number
A5551
Product name
Br-Mmc (=4-Bromomethyl-7-methoxycoumarin)[for HPLC Labeling]
Purity
>98.0%(T)
Packaging
5g
Price
$272
Updated
2024/03/01
TRC
Product number
B685400
Product name
4-Bromomethyl-7-methoxycoumarin
Packaging
1g
Price
$90
Updated
2021/12/16
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4-Bromomethyl-7-methoxycoumarin Chemical Properties,Usage,Production

Chemical Properties

Light Green-Yellow Crystals

Uses

4-Bromomethyl-7-methoxycoumarin has been used:

  • as derivatization reagent in determination of 5-fluorouracil (5-FU) in human plasma by HPLC-tandem mass spectrometry
  • as derivatization reagent in fluorescence detection of sodium monofluoroacetate (MFA-Na) in biological samples by HPLC
  • in the synthesis of new caged derivatives of hydrolysis-resistant 8-bromoadenosine cyclic 3′,5′-monophosphate (8-Br-cAMP) and 8-bromoguanosine cyclic 3′,5′-monophosphate (8-Br-cGMP)
  • in TLC and HPLC separation and fluorometric analysis of a wide range of naturally occurring acids, including bile and thromboxane B2

Uses

4-Bromomethyl-7-methoxycoumarin can be used as fluorescent label for fatty acids. For derivatization, TLC and HPLC separation, and fluorometric analysis of a wide range of naturally occurring acids, including bile and thromboxane B2.

Purification Methods

The coumarin crystallises from boiling AcOH; the crystals are washed with AcOH, EtOH and dried in a vacuum; 1HNMR (TFA) 3.97s, 4.57s, 6.62s, 6.92-7.19m and 7.80d. [Secrist et al. Biochem Biophys Res Commun 45 1262 1971, Dünges Anal Chem 49 442 1977, Beilstein 18 III/IV 348.]

4-Bromomethyl-7-methoxycoumarin Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Bromomethyl-7-methoxycoumarin Suppliers

Americas 1 Belgium 1 Canada 2 China 111 Europe 3 France 1 Germany 2 India 7 Japan 2 Slovakia 1 South Korea 1 Switzerland 3 United Kingdom 11 United States 22 USA 1 Global 169
TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
Advantage
80
Dojindo Molecular Technologies, Inc.
Tel
--
Fax
--
Email
sasamoto@dojindo.co.jp
Country
Japan
ProdList
322
Advantage
75
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View Lastest Price from 4-Bromomethyl-7-methoxycoumarin manufacturers

Honest Joy Holdings Limited
Product
4-Bromomethyl-7-methoxycoumarin 35231-44-8
Price
US $0.00/KG
Min. Order
1KG
Purity
98.7%
Supply Ability
100 tons
Release date
2022-01-14
Dideu Industries Group Limited
Product
4-Bromomethyl-7-methoxycoumarin 35231-44-8
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-10-29
Career Henan Chemical Co
Product
4-Bromomethyl-7-methoxycoumarin 35231-44-8
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1kg,5kg,100kg
Release date
2019-07-04

35231-44-8, 4-Bromomethyl-7-methoxycoumarinRelated Search:

Coumarin 6-Methylcoumarin 7-Methoxycoumarin Bromotrimethylsilane 4-Bromomethylbenzoic acid (Trifluoromethoxy)benzene 4-Methylcumarin SCOPARONE 7-Methoxy-4-methylcoumarin 3-Hydroxyphenyl acetate Allyl bromide 4-BROMOMETHYL-6,7-DIMETHOXYCOUMARIN Methyl 3-methyl-2-butenoate 3,3-Dimethylacrylic acid Methyl 4-bromocrotonate 3-METHOXYPHENYL ACETATE Methyl bromide 4-METHOXYPHENETHYL BROMIDE

  • Br-Mmc (=4-Bromomethyl-7-methoxycoumarin) [for HPLC Labeling]
  • BR-MMC (=4-BROMOETHYL-7-METHOXYCOUMARIN)
  • 4-BROMOMETHYL-7-METHOXYCOUMARIN [FOR HPLC LABELING]
  • BMC, Br-Mmc
  • 2H-1-Benzopyran-2-one, 4-(bromomethyl)-7-methoxy-
  • 4-(Bromomethyl)-7-methoxychromen-2-one
  • 4-(Bromomethyl)-7-methoxy-2H-1-benzopyran-2-one
  • 7-Methoxy-4-bromomethylcoumarin
  • 4-bromomethyl-7-hydroxycoumarin
  • 4-(Bromomethyl)-7-methoxycoumarin,99%
  • 4-(Bromomethyl)-7-methoxycoumarin,97%
  • Br-Mmc (=4-Bromomethyl-7-methoxycoumarin)
  • 4-Bromomethyl-7-methoxycoumarin,BMC, Br-Mmc
  • 4-Bromomethyl-7-methoxycoumarin (BrMMC) [for HPLC Labeling]
  • BROMOMETHYL-7-METHOXYCOUMARIN, 4-(RG)
  • 4-(BroMoMethyl)-7-MethoxycouMarin, 97% 1GR
  • 4-BroMoMethyl-7-MethoxycouMarine
  • 4-BroMoMethyl-7-MethoxycouMarin 97%
  • 4-(BroMoMethyl)-7-Methoxy-2H-chroMen-2-one
  • BR-MMC
  • BMC
  • 4-BROMOMETHYL-7-METHOXYCOUMARIN
  • 4-BROMOETHYL-7-METHOXYCOUMARIN
  • 4-BROMOMETHYL-7-METHOXYCOUMARIN, FOR FLU ORESCENCE
  • 4-Bromomethyl-7-methoxycoumain
  • 4-BROMOMETHYL-7-METHOXYCOUMARIN (BR-MMC)
  • Br-Mmc (=4-Bromomethyl-7-methoxycoumarin)[for HPLC Labeling]&gt
  • 4-Bromomethyl-7-methoxycoumarin ISO 9001：2015 REACH
  • 4-(bromomethyl)-7-methoxy-2H-chromene-2-one
  • -7-methoxy-2H-chromen-2-one
  • Br-Mmc (=4-Bromomethyl-7-methoxycoumarin), for HPLC，≥ 98.0%
  • 35231-44-8
  • C11H9BrO3
  • ESTER
  • HPLC Labeling Reagents
  • Fluorescence Detection (HPLC Labeling Reagents)
  • Carboxyl Group Labeling Reagents for Fluorescence HPLC
  • Detection
  • Fluorescent Labels
  • Fluorescent Probes, Labels, Particles and Stains
  • Other Fluorescent Labels
  • Biochemicals and Reagents
  • BioChemical
  • Carboxyl Group Labeling Reagents for Fluorescence HPLC
  • Fluorescence Detection (HPLC Labeling Reagents)
  • HPLC Labeling Reagents
  • Fluorescent Labels & Indicators
  • Fluorescent Labels and Indicators
  • Coumarins
  • Analytical Chemistry