1-Bromo-3,4,5-trimethoxybenzene

Product Name: 1-Bromo-3,4,5-trimethoxybenzene
CAS No.: 2675-79-8
Chemical Name: 1-Bromo-3,4,5-trimethoxybenzene
Synonyms: 5-BROMO-1,2,3-TRIMETHOXYBENZENE;3,4,5-Trimethoxybrombenzene;BROMOTRIMETHOXYBENZENE;3,4,5-Trimethoxybromoben;3,4,5-TRIMETHOXYBROMOBENZENE;3,4,5-rimethoxyboromobenzene;3,4,5-Trimethoxyphenyl bromide;3,4,5-triemethoxyphenylbromide;1-BROMO-3,4,5-TRIMETHOXYBENZENE;5-Bromopyrogallol trimethyl ether
CBNumber: CB6354163
Molecular Formula: C9H11BrO3
Formula Weight: 247.09
MOL File: 2675-79-8.mol

More

Less

1-Bromo-3,4,5-trimethoxybenzene Property

Melting point:: 78-82 °C(lit.)
Boiling point:: 273°C/747mmHg(lit.)
Density: 1.5463 (rough estimate)
refractive index: 1.4730 (estimate)
storage temp.: Sealed in dry,Room Temperature
form: powder to crystal
color: White to Light yellow to Light orange
Water Solubility: Insoluble in water.
InChI: InChI=1S/C9H11BrO3/c1-11-7-4-6(10)5-8(12-2)9(7)13-3/h4-5H,1-3H3
InChIKey: XAOOZMATJDXDQJ-UHFFFAOYSA-N
SMILES: C1(OC)=CC(Br)=CC(OC)=C1OC
CAS DataBase Reference: 2675-79-8(CAS DataBase Reference)

More

Less

Safety

Hazard Codes: Xi
Risk Statements: 43
Safety Statements: 22-36/37
WGK Germany: 3
Hazard Note: Irritant
HS Code: 2909309090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H317May cause an allergic skin reaction

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 634530
Product name: 5-Bromo-1,2,3-trimethoxybenzene
Purity: 97%
Packaging: 10g
Price: $144.4
Updated: 2025/07/31

Sigma-Aldrich

Product number: 634530
Product name: 5-Bromo-1,2,3-trimethoxybenzene
Purity: 97%
Packaging: 100g
Price: $256.2
Updated: 2025/07/31

TCI Chemical

Product number: B4739
Product name: 5-Bromo-1,2,3-trimethoxybenzene
Purity: >98.0%(GC)
Packaging: 5g
Price: $38
Updated: 2025/07/31

TCI Chemical

Product number: B4739
Product name: 5-Bromo-1,2,3-trimethoxybenzene
Purity: >98.0%(GC)
Packaging: 25g
Price: $149
Updated: 2025/07/31

Usbiological

Product number: 409270
Product name: 1-Bromo-3,4,5-trimethoxybenzene
Packaging: 100mg
Price: $305
Updated: 2021/12/16

More

Less

1-Bromo-3,4,5-trimethoxybenzene Chemical Properties,Usage,Production

Uses

5-Bromo-1,2,3-trimethoxybenzene is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff.

Synthesis

619-42-1

213596-33-9

2675-79-8

The general procedure for the synthesis of 1-bromo-3,4,5-trimethoxybenzene from methyl p-bromobenzoate and 2-(4-methoxyphenyl)-5,5-dimethyl-1,3,2-dioxaborole cyclohexane is as follows: aryl halide (0.67 mmol, 1.0 eq.), aryl boronate (0.81 mmol, 1.2 eq.) were added to a Schlenk tube in the following order, potassium phosphate or CsF (3.0 eq.), Pd catalyst (0.1 eq.) and 2-(dicyclohexylphosphino)biphenyl (0.2 eq.). When using Pd(OAc)2 as the catalyst, CsF is required as the base (see Table 8, entries 13-15). Subsequently, a PTFE-coated stirrer was added to the reaction system and the reaction was carried out at room temperature. The reaction mixture was degassed under high vacuum three times for 10 min each and backfilled with nitrogen. Anhydrous dioxane was added through the T-neck and the reaction mixture was heated to 110°C and kept for 18 hours. Upon completion of the reaction, the mixture was cooled to room temperature and diluted with dichloromethane (10 mL). The reaction solution was filtered and the filtrate was washed with dichloromethane (100 mL). Finally, the filtrate was concentrated and purified by silica gel column chromatography.

References

[1] Patent: WO2009/137322, 2009, A2. Location in patent: Page/Page column 21; 22; 29; 30; 31

1-Bromo-3,4,5-trimethoxybenzene Preparation Products And Raw materials

Raw materials

1,2,3-Trimethoxybenzene Urea Sodium nitrite Hydrogen bromide Diethyl ether Ethyl acetate Cuprous bromide Nitric acid Acetic acid

Preparation Products

More

Less

1-Bromo-3,4,5-trimethoxybenzene Suppliers

Americas 1 Canada 2 China 178 Europe 3 Germany 7 India 21 Japan 1 Switzerland 1 Ukraine 1 United Kingdom 14 United States 28 Global 257

Alchem Pharmtech,Inc.

Tel: 8485655694
Email: sales@alchempharmtech.com
Country: United States
ProdList: 63687
Advantage: 58

Protheragen-ING

Tel: +16313385890
Email: info@protheragen-ing.com
Country: United States
ProdList: 3868
Advantage: 58

Aladdin Scientific

Tel
Email: tp@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

BromOrganics Corporation

Tel: --
Fax: --
Email: sales@bromorganics.com
Country: United States
ProdList: 1065
Advantage: 58

Richman Chemical Inc

Tel: --
Fax: --
Email: clk@RichmanChemical.com
Country: United States
ProdList: 238
Advantage: 58

Chemphtec Corporation

Tel: --
Fax: --
Email: fo@chemphtec.com
Country: United States
ProdList: 2181
Advantage: 58

Oakwood Products, Inc.

Tel: --
Fax: --
Email: sales@oakwoodchemical.com
Country: United States
ProdList: 6193
Advantage: 74

Combi-Blocks Inc.

Tel: --
Fax: --
Email: sales@combi-blocks.com
Country: United States
ProdList: 6618
Advantage: 69

SynQuest Laboratories, Inc.

Tel: --
Fax: --
Email: info@synquestlabs.com
Country: United States
ProdList: 6871
Advantage: 62

Riedel-de Haen AG

Tel: --
Fax: --
Country: United States
ProdList: 6773
Advantage: 87

TCI America

Tel: --
Fax: --
Email: sales@tciamerica.com
Country: United States
ProdList: 6909
Advantage: 75

Matrix Scientific

Tel: --
Fax: --
Email: sales@matrixscientific.com
Country: United States
ProdList: 6632
Advantage: 80

Anvia Chemicals, LLC

Tel: --
Fax: --
Email: sales@anviachem.com
Country: United States
ProdList: 3933
Advantage: 0

ChemContract Research Inc.

Tel: --
Fax: --
Country: United States
ProdList: 1526
Advantage: 38

3B Scientific Corporation

Tel: --
Fax: --
Email: sales@3bsc.com
Country: United States
ProdList: 6962
Advantage: 56

Waterstone Technology, LLC

Tel: --
Fax: --
Email: sales@waterstonetech.com
Country: United States
ProdList: 6786
Advantage: 30

Ryan Scientific, Inc.

Tel: --
Fax: --
Email: ryan.reichlyn@ryansci.com
Country: United States
ProdList: 6439
Advantage: 60

Narchem Corporation

Tel: --
Fax: --
Email: sales@narchem.com
Country: United States
ProdList: 2813
Advantage: 60

Ivy Fine Chemicals

Tel: --
Fax: --
Email: sales@ivychem.com
Country: United States
ProdList: 6493
Advantage: 58

Alfa Aesar

Tel: --
Fax: --
Email: tech@alfa.com
Country: United States
ProdList: 6814
Advantage: 81

INDOFINE Chemical Company, Inc.

Tel: --
Fax: --
Email: chemical@indofinechemical.com
Country: United States
ProdList: 6176
Advantage: 69

2A PharmaChem USA

Tel: --
Fax: --
Email: sales@2apharmachem.com
Country: United States
ProdList: 6137
Advantage: 39

3B Scientific Corporation

Tel: --
Fax: --
Email: sales@3bsc.com
Country: United States
ProdList: 6718
Advantage: 47

HONEST JOY HOLDINGS LIMITED

Tel: --
Fax: --
Email: sales@honestjoy.cn
Country: United States
ProdList: 6675
Advantage: 54

APAC Pharmaceutical, LLC

Tel: --
Fax: --
Email: sales@apacpharma.com
Country: United States
ProdList: 6322
Advantage: 38

ASDI Incorporated

Tel: --
Fax: --
Email: customerservice@asdi.net
Country: United States
ProdList: 6922
Advantage: 67

Richman Chemical Inc.

Tel: --
Fax: --
Email: kac@richmanchemical.com
Country: United States
ProdList: 692
Advantage: 67

BOSCHE SCIENTIFIC, LLC

Tel: --
Fax: --
Email: Sales@BoscheSci.com
Country: United States
ProdList: 6477
Advantage: 55

More

Less

View Lastest Price from 1-Bromo-3,4,5-trimethoxybenzene manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 1-Bromo-3,4,5-trimethoxybenzene 2675-79-8
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-25

Hebei Yanxi Chemical Co., Ltd.

Product: 1-Bromo-3,4,5-trimethoxybenzene 2675-79-8
Price: US $80.00-45.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 20 tons
Release date: 2023-09-27

Zhuozhou Wenxi import and Export Co., Ltd

Product: 3.4.5-Trimethoxyphenylbromide 2675-79-8
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

2675-79-8, 1-Bromo-3,4,5-trimethoxybenzeneRelated Search:

o-Anisaldehyde 4-Methoxybenzoic acid 2-Bromobenzonitrile 4-Methoxybenzyl cyanide 3,4,5-Trimethoxy benzoic acid p-Anisaldehyde 3,4,5-Trimethoxyphenylacetic acid (Trifluoromethoxy)benzene 1,2,4-Trimethoxybenzene Anisole 4-Bromofluorobenzene 3-Bromoanisole 3-Methoxybenzaldehyde m-Anisyl alcohol 1,2,3-Trimethoxybenzene 1,3,5-Trimethoxybenzene 4'-Bromopropiophenone 1,3-Dibromobenzene

3,4,5-Trimethoxybrombenzene

3,4,5-Trimethoxyphenyl bromide

5-Bromo-1,2,3-trimethoxybenzene,1-Bromo-3,4,5-trimethoxybenzene

Benzene, 5-bromo-1,2,3-trimethoxy-

5-Bromo-1,2,3-trimethoxybenzene 97%

3,4,5-TRIMETHOXYBROMOBENZENE

1-BROMO-3,4,5-TRIMETHOXYBENZENE

1-Bromo-3,4,5-trimethoxybenzene 98%

5-Bromopyrogallol trimethyl ether

5-BROMO-1,2,3-TRIMETHOXYBENZENE

BROMOTRIMETHOXYBENZENE

1-Bromo-3,4,5-Trimethoxybenzene 3,4,5-Trimethoxybromobenzene

3,4,5-Trimethoxybromoben

5-Bromo-1,2,3-Trimethoxybenzene98%

3,4,5-triemethoxyphenylbromide

3.4.5-Trimethoxyphenylbromide：3.4.5-Trimethoxybromobenzene

3,4,5-rimethoxyboromobenzene

5-Bromo-1,2,3-trimethoxybenzene &gt

1-Bromo-3,4,5-trimethoxybenzene ISO 9001：2015 REACH

2675-79-8

C9H11O3Br

Building Blocks

Ethers

Organic Building Blocks

Oxygen Compounds

Pyrrolidines

Aromatic Ethers

Benzene series

Benzene derivates