3-Cyanocinnamic acid

Product Name: 3-Cyanocinnamic acid
CAS No.: 16642-93-6
Chemical Name: 3-Cyanocinnamic acid
Synonyms: AKOS BAR-2476;3-cyanocinnamicaci;RARECHEM BK HW 0149;3-CYANOCINNAMIC ACID;3-CyanocinnaMic acid, 98%+;3-(3-Cyanophenyl)acrylic acid;3-Cyanocinnamic acid USP/EP/BP;(E)-3-(3-cyanophenyl)acrylic acid;2-PROPENOIC ACID, 3-(3-CYANOPHENYL)-;2-Propenoic acid, 3-(3-cyanophenyl)-, (2E)-
CBNumber: CB6361226
Molecular Formula: C10H7NO2
Formula Weight: 173.17
MOL File: 16642-93-6.mol

More

Less

3-Cyanocinnamic acid Property

Boiling point:: 357.9±25.0 °C(Predicted)
Density: 1.26±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 4.20±0.10(Predicted)
Appearance: White to off-white Solid

More

Less

Safety

HS Code: 2918290090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

TRC

Product number: C962520
Product name: 3-CyanocinnamicAcid
Packaging: 1g
Price: $100
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC46306
Product name: 3-Cyanocinnamic acid
Packaging: 5G
Price: $150
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC46306
Product name: 3-Cyanocinnamic acid
Packaging: 2g
Price: $85
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC46306
Product name: 3-Cyanocinnamic acid
Packaging: 10g
Price: $250
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4937-1-02
Product name: 3-Cyanocinnamic acid
Packaging: 1g
Price: $264
Updated: 2021/12/16

More

Less

3-Cyanocinnamic acid Chemical Properties,Usage,Production

Uses

3-Cyanocinnamic Acid was used to synthesize triazoles with antifungal activities. It was also used to prepare aminocyclohexylethyl-substituted methylsulfonyloxy and methylsulfonyl tetrahydrobenzazepines as dopamine receptor antagonists and antipsychotics.

Synthesis

141-82-2

24964-64-5

16642-93-6

GENERAL METHOD: 3-cyanobenzaldehyde (11a) or 4-cyanobenzaldehyde (11b) (15 mmol) and malonic acid (30 mmol) were dissolved in pyridine (30 mL). Piperidine (3.0 mmol) was added to the solution and the reaction mixture was subsequently heated to reflux at 100 °C for 4 hours. Upon completion of the reaction, the mixture was cooled to room temperature and acidified by slow addition of 5 M hydrochloric acid solution (25 mL). The precipitated white precipitate was collected by filtration, washed well with water and dried to give the target products (E)-3-cyanocinnamic acid (12a) or (E)-4-cyanocinnamic acid (12b) in 81% and 78% yields, respectively.

References

[1] European Journal of Medicinal Chemistry, 2011, vol. 46, # 10, p. 5162 - 5174
[2] Journal of the American Chemical Society, 1948, vol. 70, p. 1560
[3] Bioorganic and Medicinal Chemistry, 2004, vol. 12, # 9, p. 2021 - 2034
[4] Patent: WO2006/123725, 2006, A1. Location in patent: Page/Page column 40

3-Cyanocinnamic acid Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

3-Cyanocinnamic acid Suppliers

China 74 Germany 3 United Kingdom 6 United States 7 Global 90

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Beijing Ouhe Technology Co., Ltd

Tel: 010-010-82967028 13522913783
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12000
Advantage: 60

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400 638 7771
Email: sales@heowns.com
Country: China
ProdList: 14435
Advantage: 57

Hangzhou Yuhao Chemical Technology Co., Ltd

Tel: 0571-82693216
Fax: +86-571-82880190
Email: info@yuhaochemical.com
Country: China
ProdList: 6387
Advantage: 52

Shanghai Litong Chemical Technology Co.,Ltd.

Tel: 13598610367 0373-7129549
Fax: 0373-8369699
Email: 2468833170@qq.com
Country: China
ProdList: 932
Advantage: 58

Shanghai HuanChuan Industry Co.,Ltd.

Tel: 021-61478794
Fax: 021-61478794
Email: sales@hcshhai.com
Country: China
ProdList: 9793
Advantage: 50

Shanghai Song Yuan Chemical Technology Co., Ltd.

Tel: 010-1234567 18521000990
Fax: 86-021-33275113
Email: sonyuanchemical@163.com
Country: China
ProdList: 6479
Advantage: 50

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66028182 18626450290
Email: yftan@aikonchem.com
Country: China
ProdList: 16679
Advantage: 50

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

More

Less

View Lastest Price from 3-Cyanocinnamic acid manufacturers

Career Henan Chemical Co

Product: 3-Cyanocinnamic acid 16642-93-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 25kg
Release date: 2019-07-10

16642-93-6, 3-Cyanocinnamic acidRelated Search:

Ethyl 2-(Chlorosulfonyl)acetate Ethyl cinnamate alpha-Methylcinnamic acid Propyl cinnamate Stearic acid Octyl 4-methoxycinnamate Cinnamic acid 3-(Trifluoromethyl)cinnamic acid trans-Cinnamic acid 4-Nitrocinnamic acid 3-Nitrocinnamic acid Methyl cinnamate Folic acid Citric acid 4-Methoxycinnamic acid Ascoric Acid 3-(3-CYANO-PHENYL)-ACRYLIC ACID METHYL ESTER 3-(3-CYANO-PHENYL)-2-METHYL-ACRYLIC ACID ETHYL ESTER

RARECHEM BK HW 0149

3-CYANOCINNAMIC ACID

AKOS BAR-2476

3-(3-Cyanophenyl)acrylic acid

3-CyanocinnaMic acid, 98%+

(E)-3-(3-cyanophenyl)acrylic acid

2-PROPENOIC ACID, 3-(3-CYANOPHENYL)-

2-Propenoic acid, 3-(3-cyanophenyl)-, (2E)-

3-cyanocinnamicaci

3-Cyanocinnamic acid USP/EP/BP

16642-93-6