ChemicalBook > CAS DataBase List > 4-Chloro-6-(trifluoromethyl)quinoline

4-Chloro-6-(trifluoromethyl)quinoline

Product Name
4-Chloro-6-(trifluoromethyl)quinoline
CAS No.
49713-56-6
Chemical Name
4-Chloro-6-(trifluoromethyl)quinoline
Synonyms
BUTTPARK 14\01-63;4-CHLORO-6-(TRIFLUOROMETHYL)QUINOLINE;4-Chloro-6-(trifluoroMethyl)quinolline;Quinoline, 4-chloro-6-(trifluoromethyl)-;4-Chloro-6-(trifluoromethyl)quinoline98%;4-Chloro-6-(trifluoromethyl)quinoline 98%;4-Chloro-6-(trifluoromethyl)-1-azanaphthalene
CBNumber
CB6365138
Molecular Formula
C10H5ClF3N
Formula Weight
231.6
MOL File
49713-56-6.mol
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4-Chloro-6-(trifluoromethyl)quinoline Property

Melting point:
48°C
Boiling point:
265.5±35.0 °C(Predicted)
Density 
1.427±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
2.45±0.16(Predicted)
Appearance
Pale purple to purple Solid
InChI
InChI=1S/C10H5ClF3N/c11-8-3-4-15-9-2-1-6(5-7(8)9)10(12,13)14/h1-5H
InChIKey
FTNQANJWBFKPIP-UHFFFAOYSA-N
SMILES
N1C2C(=CC(C(F)(F)F)=CC=2)C(Cl)=CC=1
CAS DataBase Reference
49713-56-6(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,T
Risk Statements 
36/37/38-36-25
Safety Statements 
26-36/37/39-45
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
2933499090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC
Product number
C381483
Product name
4-Chloro-6-(trifluoromethyl)quinoline
Packaging
100mg
Price
$75
Updated
2021/12/16
SynQuest Laboratories
Product number
3H32-7-46
Product name
4-Chloro-6-(trifluoromethyl)quinoline
Purity
98%
Packaging
250mg
Price
$20
Updated
2021/12/16
SynQuest Laboratories
Product number
3H32-7-46
Product name
4-Chloro-6-(trifluoromethyl)quinoline
Purity
98%
Packaging
1g
Price
$50
Updated
2021/12/16
Apolloscientific
Product number
PC2075L
Product name
4-Chloro-6-(trifluoromethyl)quinoline
Purity
98%
Packaging
250mg
Price
$58
Updated
2021/12/16
Matrix Scientific
Product number
002738
Product name
4-Chloro-6-(trifluoromethyl)quinoline
Purity
98%
Packaging
1g
Price
$75
Updated
2021/12/16
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4-Chloro-6-(trifluoromethyl)quinoline Chemical Properties,Usage,Production

Synthesis

49713-51-1

49713-56-6

4-Hydroxy-6-trifluoromethylquinoline (50 mg, 0.2 mmol) was used as starting material and synthesized with reference to the method reported in Bioorganic & Medicinal Chemistry Letters, 2005, 15(4), 1015-1018. The raw material was added to phosphorus trichloride (108 mg, 0.7 mmol). After the addition was completed, the reaction mixture was heated to 90 °C and stirred continuously for 2 hours. Upon completion of the reaction, the pH was adjusted to 8-9 by slow dropwise addition of saturated sodium bicarbonate solution.Subsequently, extraction was carried out with ethyl acetate (30 mL x 3). The organic phases were combined and concentrated under reduced pressure to afford the target product 4-chloro-6-(trifluoromethyl)quinoline (60 mg, colorless oil), which could be used directly in the subsequent reaction without further purification.

References

[1] Bioorganic and Medicinal Chemistry Letters, 2005, vol. 15, # 4, p. 1015 - 1018
[2] Patent: KR2016/6207, 2016, A. Location in patent: Paragraph 0188; 0191-0194
[3] Patent: US2016/108035, 2016, A1. Location in patent: Paragraph 0136-0137

4-Chloro-6-(trifluoromethyl)quinoline Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Chloro-6-(trifluoromethyl)quinoline Suppliers

China 89 France 1 Germany 3 India 4 United Kingdom 11 United States 24 Global 132
Bayee Biotech (Anqing) Co., Ltd.
Tel
0556-5032306 18917961636
Email
wtx@bayeebio.com
Country
China
ProdList
239
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61
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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76
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
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56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
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66
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel
+86-21-54098501
Fax
+86-21-54096319
Email
sales@sinch.com.cn
Country
China
ProdList
11598
Advantage
64
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
15883
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Shanghai Ennopharm Co., Ltd.
Tel
+86 (21) 6435-5022
Country
China
ProdList
4267
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65
Chengdu Forest Science and Technology Development Co., Ltd.
Tel
18030648795
Fax
028-61777050
Email
sales@cdforestchem.com
Country
China
ProdList
1997
Advantage
58
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View Lastest Price from 4-Chloro-6-(trifluoromethyl)quinoline manufacturers

Career Henan Chemical Co
Product
4-Chloro-6-(trifluoromethyl)quinoline 49713-56-6
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kg
Release date
2019-12-31

49713-56-6, 4-Chloro-6-(trifluoromethyl)quinolineRelated Search:

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  • 4-CHLORO-6-(TRIFLUOROMETHYL)QUINOLINE
  • BUTTPARK 14\01-63
  • 4-Chloro-6-(trifluoromethyl)quinoline 98%
  • 4-Chloro-6-(trifluoromethyl)quinoline98%
  • 4-Chloro-6-(trifluoroMethyl)quinolline
  • 4-Chloro-6-(trifluoromethyl)-1-azanaphthalene
  • Quinoline, 4-chloro-6-(trifluoromethyl)-
  • 49713-56-6
  • 99713-56-6
  • Quinoline&Isoquinoline