ISOTETRANDRINE
- Product Name
- ISOTETRANDRINE
- CAS No.
- 477-57-6
- Chemical Name
- ISOTETRANDRINE
- Synonyms
- NSC 97338;isosinomenina;ISOTETRANDRINE;isosinomeninea;1-isotetrandrine;O-METHYLBERBAMINE;(r,s)-tetrandrine;1-Isotetrandrine(8CI);o,o’-dimethylobamegine;BERBAMINE METHYL ETHER
- CBNumber
- CB6376880
- Molecular Formula
- C38H42N2O6
- Formula Weight
- 622.76
- MOL File
- 477-57-6.mol
ISOTETRANDRINE Property
- Melting point:
- 180-182℃
- Boiling point:
- 710.5±60.0 °C(Predicted)
- Density
- 1.172
- RTECS
- NX7285000
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- Off-white solid.
- pka
- 7.70±0.20(Predicted)
- color
- White to light yellow
N-Bromosuccinimide Price
- Product number
- J67081
- Product name
- Isotetrandrine, 98%
- Packaging
- 1mg
- Price
- $120
- Updated
- 2023/06/20
- Product number
- I918015
- Product name
- Isotetrandrine
- Packaging
- 50mg
- Price
- $685
- Updated
- 2021/12/16
- Product number
- INB0001324
- Product name
- ISOTETRANDRINE
- Purity
- 98.00%
- Packaging
- 1MG
- Price
- $187.95
- Updated
- 2021/12/16
- Product number
- INB0001324
- Product name
- ISOTETRANDRINE
- Purity
- 98.00%
- Packaging
- 25MG
- Price
- $1270.5
- Updated
- 2021/12/16
- Product number
- AS325629
- Product name
- Isotetrandrine
- Packaging
- 5mg
- Price
- $226
- Updated
- 2021/12/16
ISOTETRANDRINE Chemical Properties,Usage,Production
Description
A bisbenzylisoquinoline alkaloid, shown to be identical with berbamine methyl ether, this base occurs in A therosperrna rnoschaturn, Berberis japonica and Stephania cephalantha. It is dextrorotatory with [α]17D + 146° or[α]20D + 150.7° (c 0.85, CHC13). When recrystallized from MeOH it forms colourless crystals and furnishes a crystalline dimethiodide, m.p. 242°C. Four methoxyl groups and two methylimino groups are present.
Uses
Isotetrandrine is a biscoclaurine alkaloid inhibitor of G protein activation of PLA2.
target
IL Receptor | NF-kB | MAPK | Nrf2 | HO-1 | JNK
References
Kondo et al., J. Pharrn. Soc., Japan, 58,920 (1938)
Tomita, Fujita, Morai., ibid, 71,226,301 (1951)
Bick, Clezy, Crow., Austral. J. Chern., 9, III (1956)
Synthesis:
Inubushi et ai., Tetrahedron Lett., 3399 (1968)
ISOTETRANDRINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from ISOTETRANDRINE manufacturers
- Product
- Isotetrandrine 477-57-6
- Price
- US $30.00-20.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200000KG
- Release date
- 2024-08-06
- Product
- ISOTETRANDRINE 477-57-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98% HPLC
- Supply Ability
- 10 tons
- Release date
- 2020-03-12