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PINOCEMBRIN

Product Name
PINOCEMBRIN
CAS No.
68745-38-0
Chemical Name
PINOCEMBRIN
Synonyms
NSC 43318;PINOCEMBRIN;(±)-Pinocchio;(±)-Pinocchio;DL-Pinocembrin;rac-PinoceMbrin;(±)-Pinocembrin;(+/-)-Pinocembrin;5,7-DIHYDROXYFLAVANONE;5,7- Dihyroxy Flavanone
CBNumber
CB6378884
Molecular Formula
C15H12O4
Formula Weight
256.25
MOL File
68745-38-0.mol
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PINOCEMBRIN Property

Melting point:
202-203°C
Boiling point:
511.1±50.0 °C(Predicted)
Density 
1.386±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Chloroform (Slightly, heated), DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
7.50±0.40(Predicted)
color 
White to Pale Beige
Major Application
food and beverages
InChI
1S/C15H12O4/c16-10-6-11(17)15-12(18)8-13(19-14(15)7-10)9-4-2-1-3-5-9/h1-7,13,16-17H,8H2/t13-/m0/s1
InChIKey
URFCJEUYXNAHFI-ZDUSSCGKSA-N
SMILES
OC1=CC(OC(C2=CC=CC=C2)C3)=C(C(O)=C1)C3=O
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Safety

WGK Germany 
WGK 3
Storage Class
11 - Combustible Solids
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHL80061
Product name
Pinocembrin
Purity
phyproof? Reference Substance
Packaging
10MG
Price
$332
Updated
2026/03/19
TRC
Product number
P468495
Product name
rac-Pinocembrin
Packaging
250mg
Price
$185
Updated
2021/12/16
Usbiological
Product number
300792
Product name
Pinocembrin
Packaging
20mg
Price
$390
Updated
2021/12/16
Usbiological
Product number
019734
Product name
Pinocembrin
Packaging
50mg
Price
$460
Updated
2021/12/16
Biosynth Carbosynth
Product number
FP66340
Product name
Pinocembrin
Packaging
10mg
Price
$45
Updated
2021/12/16
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PINOCEMBRIN Chemical Properties,Usage,Production

Uses

Pinocembrin is a flavanoid with antioxidant activity found in damiana, honey, and propolis. Recent studies show that Pinocembrin maybe be a therapeutic option in reducing cerebral ischemia/reperfusion injury as a result of its anti-oxidative and anti-apoptotic effects. Pinocembrin displayed neuroprotective effects in glutamate injury model partly by inhibiting p53 expression causing a lower Bax-Bcl-2 ratio and by inhibiting the release of cytochrome c.

Synthesis

The synthesis of biopinein was carried out by the traditional chalcone closed-loop synthetic route, which requires chemical reagents that have the disadvantage of polluting the environment, reacting under drastic conditions, and consuming large amounts of energy. In addition, the product obtained by the chemical method is a mixture of racemates (R-type, S-type), whereas studies have demonstrated that only (2S)-biopsin is biologically active. Therefore, the chemical synthesis method is not suitable for the mass production of biopines.

PINOCEMBRIN Preparation Products And Raw materials

Raw materials

Preparation Products

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PINOCEMBRIN Suppliers

J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Shandong Xiya Chemical Co., Ltd
Tel
13355009207 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18729
Advantage
57
Chengdu Biopurify Phytochemicals Ltd.
Tel
+86-028-82633397 18982077548
Fax
+86-28-82633165
Email
cwb1@biopurify.cn
Country
China
ProdList
2376
Advantage
60
Chengdu Climax Biotech Co., Ltd.
Tel
028-83311324 1278112614
Fax
028-83311324
Email
climaxbiotech@gmail.com
Country
China
ProdList
925
Advantage
58
Shanghai Tauto Biotech Co., Ltd.
Tel
021-51320588
Fax
0086-21-51320502
Email
tauto@tautobiotech.com
Country
China
ProdList
3988
Advantage
66
Bide Pharmatech Ltd.
Tel
400-400-164-7117 18317119277
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
40000
Advantage
60
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15178
Advantage
58
ALB Technology Limited
Tel
702-983-3769
Fax
702-983-3769
Email
sales@albtechnology.com
Country
United States
ProdList
2993
Advantage
55
Wuhan ChemFaces Biochemical Co., Ltd.
Tel
18607101326 15172504745
Fax
+86-27-84254680
Email
aileen@chemfaces.com
Country
China
ProdList
6905
Advantage
55

68745-38-0, PINOCEMBRINRelated Search:


  • PINOCEMBRIN
  • 5,7-DIHYDROXY-2-PHENYL-CHROMAN-4-ONE
  • 5,7-DIHYDROXY-3'4'5'-FLAVANONE
  • 5,7-DIHYDROXYFLAVANONE
  • 2-Phenyl-5,7-dihydroxy-3,4-dihydro-2H-1-benzopyran-4-one
  • 5,7-Dihydroxy-2,3-dihydro-2-phenyl-4H-1-benzopyran-4-one
  • 5,7-Dihydroxy-2-phenyl-4-chromanone
  • 5,7-dihydroxy-2-phenyl-2,3-dihydrochromen-4-one
  • NSC 43318
  • rac-PinoceMbrin
  • DL-Pinocembrin
  • (2R)-5,7-dihydroxy-2-phenyl-3,4-dihydro-2H-1-benzopyran-4-one
  • 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-phenyl-
  • 5,7-Dihydroxyflavanone (Pinocembrin)
  • (±)-Pinocchio
  • Pinocembrin racemate (DL0108)
  • (+/-)-Pinocembrin
  • 5,7- Dihyroxy Flavanone
  • NSC 43318|||(±)-5,7-Dihydroxyflavanone
  • (±)-Pinocembrin
  • (±)-Pinocchio
  • (±)-Pinocembrin ((±)-5,7-Dihydroxyflavanone)
  • 68745-38-0
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  • Chemical Structure
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