PINOCEMBRIN
- Product Name
- PINOCEMBRIN
- CAS No.
- 68745-38-0
- Chemical Name
- PINOCEMBRIN
- Synonyms
- NSC 43318;PINOCEMBRIN;(±)-Pinocchio;(±)-Pinocchio;DL-Pinocembrin;rac-PinoceMbrin;(±)-Pinocembrin;(+/-)-Pinocembrin;5,7-DIHYDROXYFLAVANONE;5,7- Dihyroxy Flavanone
- CBNumber
- CB6378884
- Molecular Formula
- C15H12O4
- Formula Weight
- 256.25
- MOL File
- 68745-38-0.mol
PINOCEMBRIN Property
- Melting point:
- 202-203°C
- Boiling point:
- 511.1±50.0 °C(Predicted)
- Density
- 1.386±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- Chloroform (Slightly, heated), DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 7.50±0.40(Predicted)
- color
- White to Pale Beige
- Major Application
- food and beverages
- InChI
- 1S/C15H12O4/c16-10-6-11(17)15-12(18)8-13(19-14(15)7-10)9-4-2-1-3-5-9/h1-7,13,16-17H,8H2/t13-/m0/s1
- InChIKey
- URFCJEUYXNAHFI-ZDUSSCGKSA-N
- SMILES
- OC1=CC(OC(C2=CC=CC=C2)C3)=C(C(O)=C1)C3=O
Safety
- WGK Germany
- WGK 3
- Storage Class
- 11 - Combustible Solids
N-Bromosuccinimide Price
- Product number
- PHL80061
- Product name
- Pinocembrin
- Purity
- phyproof? Reference Substance
- Packaging
- 10MG
- Price
- $332
- Updated
- 2026/03/19
- Product number
- P468495
- Product name
- rac-Pinocembrin
- Packaging
- 250mg
- Price
- $185
- Updated
- 2021/12/16
- Product number
- 300792
- Product name
- Pinocembrin
- Packaging
- 20mg
- Price
- $390
- Updated
- 2021/12/16
- Product number
- 019734
- Product name
- Pinocembrin
- Packaging
- 50mg
- Price
- $460
- Updated
- 2021/12/16
- Product number
- FP66340
- Product name
- Pinocembrin
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
PINOCEMBRIN Chemical Properties,Usage,Production
Uses
Pinocembrin is a flavanoid with antioxidant activity found in damiana, honey, and propolis. Recent studies show that Pinocembrin maybe be a therapeutic option in reducing cerebral ischemia/reperfusion injury as a result of its anti-oxidative and anti-apoptotic effects. Pinocembrin displayed neuroprotective effects in glutamate injury model partly by inhibiting p53 expression causing a lower Bax-Bcl-2 ratio and by inhibiting the release of cytochrome c.
Synthesis
The synthesis of biopinein was carried out by the traditional chalcone closed-loop synthetic route, which requires chemical reagents that have the disadvantage of polluting the environment, reacting under drastic conditions, and consuming large amounts of energy. In addition, the product obtained by the chemical method is a mixture of racemates (R-type, S-type), whereas studies have demonstrated that only (2S)-biopsin is biologically active. Therefore, the chemical synthesis method is not suitable for the mass production of biopines.
PINOCEMBRIN Preparation Products And Raw materials
Raw materials
Preparation Products
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