ChemicalBook > CAS DataBase List > 1-(4-HYDROXY-3-METHOXYPHENYL)-2-NITROETHENE

1-(4-HYDROXY-3-METHOXYPHENYL)-2-NITROETHENE

Product Name
1-(4-HYDROXY-3-METHOXYPHENYL)-2-NITROETHENE
CAS No.
6178-42-3
Chemical Name
1-(4-HYDROXY-3-METHOXYPHENYL)-2-NITROETHENE
Synonyms
2-METHOXY-4-(2-NITROVINYL)PHENOL;AURORA 3504;vanillalnitromethane;4-HYDROXY-3-METHOXYNITROSTYRENE;2-Methoxy-4-(2-nitroethenyl)phenol;β-Nitro-3-methoxy-4-hydroxystyrene;4-Hydroxy-3-methoxy-β-nitrostyrene;(E)-2-methoxy-4-(2-nitrovinyl)phenol;4-Hydroxy-3-methoxy-beta-nitrostyrene;3-METHOXY-4-HYDROXY-BETA-NITROSTYRENE
CBNumber
CB6386535
Molecular Formula
C9H9NO4
Formula Weight
195.17
MOL File
6178-42-3.mol
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1-(4-HYDROXY-3-METHOXYPHENYL)-2-NITROETHENE Property

Melting point:
168-170 °C (lit.)
Boiling point:
347.0±27.0 °C(Predicted)
Density 
1.308±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Dichloromethane, Ethyl Acetate, Methanol
form 
Solid
pka
8.09±0.18(Predicted)
color 
Brown
CAS DataBase Reference
6178-42-3(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
Hazard Note 
Irritant
HS Code 
2904200090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S594636
Product name
4-HYDROXY-3-METHOXY-BETA-NITROSTYRENE
Purity
AldrichCPR
Packaging
50mg
Price
$29.8
Updated
2024/03/01
TRC
Product number
H946230
Product name
4-Hydroxy-3-methoxy-β-nitrostyrene
Packaging
2.5g
Price
$185
Updated
2021/12/16
AK Scientific
Product number
9265AB
Product name
trans-4-Hydroxy-3-methoxy-beta-nitrostyrene
Packaging
25g
Price
$358
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
58849
Product name
4-Hydroxy-3-methoxy-β-nitrostyrene
Packaging
2.5g
Price
$675
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0032462
Product name
1-(4-HYDROXY-3-METHOXYPHENYL)-2-NITROETHENE
Purity
95.00%
Packaging
25G
Price
$1261.26
Updated
2021/12/16
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1-(4-HYDROXY-3-METHOXYPHENYL)-2-NITROETHENE Chemical Properties,Usage,Production

Chemical Properties

Brown Solid

Uses

β-Nitrostyrene derivative, with inhibitory activity of Src and/or Syk kinase and antibacterial activity.

Uses

trans-4-Hydroxy-3-methoxy-β-nitrostyrene may be used in the synthesis of cytotoxic β-nitrostyrene derivatives, 4-O-benzoyl-3-methoxy-β-nitrostyrene (BMNS) derivatives.

Synthesis Reference(s)

Journal of the American Chemical Society, 72, p. 2781, 1950 DOI: 10.1021/ja01162a521

General Description

trans-4-Hydroxy-3-methoxy-β-nitrostyrene is a phenolic β-nitrostyrene. Synthesis of 4-hydroxy-3-methoxy-β-nitrostyrene is reported.

1-(4-HYDROXY-3-METHOXYPHENYL)-2-NITROETHENE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(4-HYDROXY-3-METHOXYPHENYL)-2-NITROETHENE Suppliers

J & K SCIENTIFIC LTD.
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6178-42-3, 1-(4-HYDROXY-3-METHOXYPHENYL)-2-NITROETHENERelated Search:


  • 4-Hydroxy-3-methoxy-beta-nitrostyrene
  • AURORA 3504
  • 1-(4-HYDROXY-3-METHOXYPHENYL)-2-NITROETHENE
  • 2-METHOXY-4-((E)-2-NITRO-VINYL)-PHENOL
  • 2-METHOXY-4-(2-NITROVINYL)PHENOL
  • 4-HYDROXY-3-METHOXYNITROSTYRENE
  • TRANS-4-HYDROXY-3-METHOXY-BETA-NITROSTYRENE
  • TRANS-2-METHOXY-4-(2-NITROVINYL)PHENOL
  • 1-(4-HYDROXY-3-METHOXYPHENYL)-2-NITROETHYLENE
  • trans-4-hydroxy-3-methoxy-β-nitrostyrene
  • trans-2-Methoxy-4-(2-nitrovinyl)phenol 98%
  • 3-METHOXY-4-HYDROXY-BETA-NITROSTYRENE
  • 4-HYDROXY-3-METHOXY-BETA-NITROSTYRENE, >95%
  • trans-4-Hydroxy-3-methoxy-beta-nitrostyrene 98%
  • 2-Methoxy-4-[(E)-2-nitrovinyl]phenol98%
  • 1-(2-Nitroethenyl)-3-methoxy-4-hydroxybenzene
  • 2-Methoxy-4-(2-nitroethenyl)phenol
  • β-Nitro-3-methoxy-4-hydroxystyrene
  • 2-Methoxy-4-[(E)-2-nitrovinyl]phenol 98%
  • trans-4-Hydroxy-3-methoxy-beta-nitrostyrene, 2-Hydroxy-5-[(E)-2-nitroethenyl]anisole
  • Phenol, 2-methoxy-4-(2-nitroethenyl)-
  • (E)-2-methoxy-4-(2-nitrovinyl)phenol
  • 4-Hydroxy-3-methoxy-β-nitrostyrene
  • vanillalnitromethane
  • 6178-42-3
  • CH3OC6H3CHCHNO2OH
  • C9H9NO8
  • Organic Building Blocks
  • Alkenes
  • Acyclic
  • Building Blocks
  • Acyclic
  • Alkenes
  • Bioactive Small Molecules
  • Building Blocks
  • Cell Biology
  • Chemical Synthesis
  • H
  • Organic Building Blocks
  • Ethanes/ethenes