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Oxiconazole

Product Name
Oxiconazole
CAS No.
64211-45-6
Chemical Name
Oxiconazole
Synonyms
OXICONAZOLE;Oxiconazolum;OXICONAZOLC NITRATE;Oxiconazole Nitarte;1-(2,4-dichlorophenyl)-N-[(2,4-dichlorophenyl)methoxy]-2-(1-imidazolyl)ethanimine;1-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-yl)-ethanone O-(2,4-dichlorobenzyl) oxime;1-(2,4-Dichlorophenyl)-N-[(2,4-dichlorophenyl)methoxy]-2-imidazol-1-yl-ethanimine;Ethanone, 1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)-, O-[(2,4-dichlorophenyl)methyl]oxime, (1Z)-
CBNumber
CB6394620
Molecular Formula
C18H13Cl4N3O
Formula Weight
429.13
MOL File
64211-45-6.mol
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Oxiconazole Property

Boiling point:
576.8±60.0 °C(Predicted)
Density 
1.42±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
pka
6.14±0.12(Predicted)
CAS DataBase Reference
64211-45-6(CAS DataBase Reference)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
O846803
Product name
Oxiconazole
Packaging
100mg
Price
$625
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0014815
Product name
OXICONAZOLE
Purity
95.00%
Packaging
100MG
Price
$885.31
Updated
2021/12/16
AHH
Product number
API-1195
Product name
Oxiconazole
Purity
98%
Packaging
0.5g
Price
$720
Updated
2021/12/16
Alichem
Product number
64211456
Product name
1-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-yl)ethanoneO-(2,4-dichlorobenzyl)oxime
Packaging
1g
Price
$304.92
Updated
2021/12/16
Chemenu
Product number
CM129214
Product name
(E)-1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethan-1-oneO-(2,4-dichlorobenzyl)oxime
Purity
95%
Packaging
1g
Price
$356
Updated
2021/12/16
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Oxiconazole Chemical Properties,Usage,Production

Description

Oxiconazole is a substituted imidazole derivative,it is structurally distinct from miconazole, econazole, clotrimazole, and ketoconazole because it is an acetophene-oxime derivative. It has a broad spectrum of antifungal activity including activity against yeasts, dermatophytes, and Aspergillus species.

Uses

Antifungal.
Oxiconazole (Oxistat) is a synthetic imidazole that works, in part, by inhibiting ergosterol 2,3-epoxidase synthesis and thereby disrupting cell membrane integrity.

Uses

Oxiconazole is used as an antifungal agent.

Indications

Topical treatment of mycoses of the skin induced or sustained by fungi such as dermatophytes and yeasts. In addition, oxiconazole is indicated for therapy of vulvovaginal mycoses caused by Candida species and Candida (Torulopsis) glabrata.

Definition

ChEBI: An oxime O-ether that is the 2,4-dichlorobenzyl ether of the oxime obtained by formal condensation of hydroxylamine with the carbonyl group of acetopnenone in which the phenyl group is substituted by chlorines at positions 2 and 4, and i which one of the hydrogens of the methyl group is replaced by a 1H-imidazol-1-yl group. An antifungal agent, it is used (generally as the nitrate salt) in creams and powders for the topical treatment of fungal skin infections.

brand name

Oxistat (Altana).

Antimicrobial activity

Broad-specktrum imidazole antimycotic with activity against almost all species of pathogenic fungi.

Side effects

Local irritations such as itching and burning sensations, and allergic reactions may occur in rare cases and are mainly due to the galenic formulation.

Oxiconazole Preparation Products And Raw materials

Raw materials

Preparation Products

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64211-45-6, OxiconazoleRelated Search:


  • OXICONAZOLC NITRATE
  • OXICONAZOLE
  • 1-(2,4-Dichlorophenyl)-N-[(2,4-dichlorophenyl)methoxy]-2-imidazol-1-yl-ethanimine
  • 1-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-yl)-ethanone O-(2,4-dichlorobenzyl) oxime
  • 1-(2,4-dichlorophenyl)-N-[(2,4-dichlorophenyl)methoxy]-2-(1-imidazolyl)ethanimine
  • Oxiconazole Nitarte
  • Ethanone, 1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)-, O-[(2,4-dichlorophenyl)methyl]oxime, (1Z)-
  • Oxiconazolum
  • 64211-45-6
  • C18H13N3OCl4HNO3
  • C18H13Cl4N3O
  • Active Pharmaceutical Ingredients