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Diethyl methylmalonate

Product Name
Diethyl methylmalonate
CAS No.
609-08-5
Chemical Name
Diethyl methylmalonate
Synonyms
Diethyl 2-methylmalonate;METHYLMALONIC ACID DIETHYL ESTER;RARECHEM AL BI 0301;Diethylisosuccinate;Diethyl methylmalote;Diethyl methylmalona;Ethyl methylmalonate;Diethyl MethyMalonate;dlethylmethylmalonate;DIETHYL METHYLMALONATE
CBNumber
CB6410788
Molecular Formula
C8H14O4
Formula Weight
174.19
MOL File
609-08-5.mol
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Diethyl methylmalonate Property

Boiling point:
198-199 °C (lit.) 78-80 °C/10 mmHg
Density 
1.022 g/mL at 20 °C (lit.)
refractive index 
n20/D 1.413(lit.)
Flash point:
170 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
1000mg/l
form 
Liquid
pka
13.13±0.46(Predicted)
Specific Gravity
1.013
color 
Clear colorless
PH
8 (1000mg/l, H2O, 20℃)
Water Solubility 
immiscible
BRN 
637028
InChIKey
UPQZOUHVTJNGFK-UHFFFAOYSA-N
LogP
1.256 (est)
CAS DataBase Reference
609-08-5(CAS DataBase Reference)
NIST Chemistry Reference
Propanedioic acid, methyl-, diethyl ester(609-08-5)
EPA Substance Registry System
Propanedioic acid, methyl-, diethyl ester (609-08-5)
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Safety

Safety Statements 
23-24/25
WGK Germany 
3
TSCA 
Yes
HS Code 
29171990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H227Combustible liquid

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
126136
Product name
Diethyl methylmalonate
Purity
99%
Packaging
100g
Price
$72.8
Updated
2024/03/01
Sigma-Aldrich
Product number
126136
Product name
Diethyl methylmalonate
Purity
99%
Packaging
500g
Price
$262
Updated
2024/03/01
TCI Chemical
Product number
M0366
Product name
Diethyl Methylmalonate
Purity
>98.0%(GC)
Packaging
25mL
Price
$21
Updated
2024/03/01
TCI Chemical
Product number
M0366
Product name
Diethyl Methylmalonate
Purity
>98.0%(GC)
Packaging
100mL
Price
$49
Updated
2024/03/01
Alfa Aesar
Product number
A12078
Product name
Diethyl methylmalonate, 99%
Packaging
50g
Price
$27.65
Updated
2024/03/01
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Diethyl methylmalonate Chemical Properties,Usage,Production

Chemical Properties

Colorless mobile liquid. Slightly soluble in water, soluble in alcohol and oils.

Physical properties

Colorless mobile liquid. Slightly soluble in water, soluble in alcohol and oils.

Uses

Diethyl methylmalonate is used as intermediate for the syntheses of pharmaceuticals, e.g. non-steroidal anti-inflammatory agents with 2-acrylpropionic acid structures acrylpropionic acid structure. It is also used in the flavour and fragrance industries. Product Data Sheet

Uses

Diethyl methylmalonate was used to investigate the effect of direct supplementation of the medium with di-ester of methylmalonate on erythromycin fermentation in Saccharopolyspora erythraea mutB strain.

General Description

Diethyl methylmalonate reacts with 2-cyclohexenone under abnormal Michael conditions form 2-(3-oxocyclohexyl)-2-cyclohexenone. It causes the alkylation of poly(chloromethylstyrene) during pahse transfer catalysis.

Synthesis

Diethyl methylmalonate is produced by the following method:1) by condensing Ethylpropionate with Diethyloxalate, followed by heating of the reaction product. 2) from Diethylmalonate plus Sodium and Methyl iodide.

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Diethyl methylmalonate Suppliers

Dongyang Baihang Chemical Co., Ltd.
Tel
0579-86886233 18006543966
Fax
QQ:355093164
Email
355093164@qq.com
Country
China
ProdList
103
Advantage
58
Shandong Vantage Specialty Chemicals Biotechnology Co., Ltd.
Tel
133-96369453 18678026865
Fax
0536-2101172
Email
sdfantai@163.com
Country
China
ProdList
862
Advantage
58
Nanjing Hengweisheng Pharmaceutical Technology Co., Ltd
Tel
19941530336
Email
3991044086@qq.com
Country
China
ProdList
682
Advantage
58
Zibo Chuanggu Chemical Technology Co., Ltd.
Tel
00-15864498288 15864498288
Email
15864498288@163.cn
Country
China
ProdList
43
Advantage
58
Nanjing Dilu Pharmaceutical Co., Ltd
Tel
18014482516
Email
977144864@qq.com
Country
China
ProdList
402
Advantage
58
Creasyn Finechem(Tianjin) Co., Ltd.
Tel
022-83946278 13820503911
Fax
022-83945176
Email
sales@creasyn.com
Country
China
ProdList
978
Advantage
68
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1995
Advantage
65
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
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View Lastest Price from Diethyl methylmalonate manufacturers

Hebei Kingfiner Technology Development Co.Ltd
Product
Diethyl methylmalonate 609-08-5
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
50000kg
Release date
2023-08-11
Hebei Weibang Biotechnology Co., Ltd
Product
Diethyl methylmalonate 609-08-5
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
5tons
Release date
2021-11-02
Henan Fengda Chemical Co., Ltd
Product
Diethyl methylmalonate 609-08-5
Price
US $35.00-1.10/kg
Min. Order
1kg
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-19

609-08-5, Diethyl methylmalonateRelated Search:


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  • 609-08-5
  • 608-08-5
  • C8H14O4
  • CH3CHCOOC2H52
  • COOC2H52CHCH3
  • Carbonyl Compounds
  • C8 to C9
  • Building Blocks
  • Esters
  • Organic Building Blocks
  • Building Blocks
  • C8 to C9
  • Carbonyl Compounds
  • Chemical Synthesis
  • Esters
  • Organic Building Blocks
  • Pharmaceutical Intermediates
  • Cyanoacetic acid esters
  • Hydrocyanic acid derivatives
  • bc0001