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2-Aminoacetophenone hydrochloride

Product Name
2-Aminoacetophenone hydrochloride
CAS No.
5468-37-1
Chemical Name
2-Aminoacetophenone hydrochloride
Synonyms
2-aMino-1-phenylethan-1-one hydrochloride;PHENACYLAMINE HYDROCHLORIDE;α-Aminoacetophenone;Compound F0401-0089;2-amino-acetophenonhydrochlo;2-aminophenone hydrochloride;2-amino-acetophenonhydrochloride;O-AMINOACETOPHENONE HYDROCHLORIDE;2-AMINOACETOPHENONE HYDROCHLORIDE;ω-aminoacetophenone hydrochloride
CBNumber
CB6412186
Molecular Formula
C8H10ClNO
Formula Weight
171.62
MOL File
5468-37-1.mol
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2-Aminoacetophenone hydrochloride Property

Melting point:
194 °C (dec.)(lit.)
storage temp. 
Refrigerator (+4°C)
solubility 
DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form 
Crystals
color 
Slightly yellow to beige
BRN 
3563173
Stability:
Hygroscopic
InChI
InChI=1S/C8H9NO.ClH/c9-6-8(10)7-4-2-1-3-5-7;/h1-5H,6,9H2;1H
InChIKey
CVXGFPPAIUELDV-UHFFFAOYSA-N
SMILES
C(C1=CC=CC=C1)(=O)CN.[H]Cl
CAS DataBase Reference
5468-37-1(CAS DataBase Reference)
EPA Substance Registry System
Ethanone, 2-amino-1-phenyl-, hydrochloride (5468-37-1)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
37/39-26-24/25
WGK Germany 
3
RTECS 
AM5940000
TSCA 
Yes
HazardClass 
IRRITANT
HS Code 
29223990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A38207
Product name
2-Aminoacetophenone hydrochloride
Purity
99%
Packaging
1g
Price
$27.72
Updated
2024/03/01
Sigma-Aldrich
Product number
A38207
Product name
2-Aminoacetophenone hydrochloride
Purity
99%
Packaging
5g
Price
$99.7
Updated
2024/03/01
Alfa Aesar
Product number
H29117
Product name
2-Aminoacetophenone hydrochloride, 97%
Packaging
1g
Price
$44.65
Updated
2024/03/01
Alfa Aesar
Product number
H29117
Product name
2-Aminoacetophenone hydrochloride, 97%
Packaging
10g
Price
$200.65
Updated
2024/03/01
Alfa Aesar
Product number
H29117
Product name
2-Aminoacetophenone hydrochloride, 97%
Packaging
50g
Price
$569
Updated
2021/12/16
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2-Aminoacetophenone hydrochloride Chemical Properties,Usage,Production

Chemical Properties

Off-white crystalline

Uses

Mixed Salt of α-Aminoacetophenone, used in the preparation og pseudopeptidic inhibitors of human sirtuins1-3. This action effectually displays antiproliferative protperties in cancer cells. Also used in the preparation of dual δ/μopiod receptor agonists.

Synthesis

To a stirred solution of phenacyl bromide (1 mmol, 1 equiv) in diethyl ether (13 mL) was added hexamethylenetetramine (1 mmol, 1 equiv) all at once and the mixture was stirred for 12 h at room temperature. The resulting solid was filtered, washed with diethyl ether (15 mL), and dried under reduced pressure to afford the quaternary salt, which was next placed in a two-necked round-bottomed flask fitted with a reflux condenser, and EtOH (22 mL) was added to it. Concentrated HCl (0.6 mL) was added, and the mixture was refluxed for 3 h (solid formed). After cooling to room temperature, the solid was filtered, washed with EtOH (20 mL), and dried under vacuum to afford pure 2-Aminoacetophenone hydrochloride.

Purification Methods

Crystallise the salt from Me2CO /EtOH, EtOH/ Et2O, 2-propanol or 2-propanol and a little HCl (slowly after a fe

2-Aminoacetophenone hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

4-PHENYLIMIDAZOLE
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2-Aminoacetophenone hydrochloride Suppliers

Belgium 1 China 222 Europe 2 Germany 5 Hungary 1 India 8 Japan 3 Slovakia 1 South Korea 1 Switzerland 2 Ukraine 1 United Kingdom 8 United States 25 Global 280
MATRIX MARKETING GMBH
Tel
--
Fax
--
Email
info@matrix-marketing.ch
Country
Switzerland
ProdList
312
Advantage
46
SIGMA-RBI
Tel
--
Fax
--
Country
Switzerland
ProdList
6896
Advantage
91
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View Lastest Price from 2-Aminoacetophenone hydrochloride manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
2-Aminoacetophenone hydrochloride 5468-37-1
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
2-Aminoacetophenone hydrochloride 5468-37-1
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-08
Zhuozhou Wenxi import and Export Co., Ltd
Product
2-Aminoacetophenone hydrochloride 5468-37-1
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27

5468-37-1, 2-Aminoacetophenone hydrochlorideRelated Search:

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  • C6H5COCH2NH2HCl
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  • Carbonyl Compounds
  • AMINE
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