5-AMINO-2-NITROPYRIDINE
- Product Name
- 5-AMINO-2-NITROPYRIDINE
- CAS No.
- 14916-65-5
- Chemical Name
- 5-AMINO-2-NITROPYRIDINE
- Synonyms
- 6-nitro-3-PyridinaMine;2-Nitro-5-pyridinamine;6-Nitropyridin-3-amine;3-Amino-6-nitropyridine;5-AMINO-2-NITROPYRIDINE;3-Pyridinamine, 6-nitro-;6-Nitro-pyridin-3-ylamine;5-Amino-2-nitropyridine95%;5-Amino-2-nitropyridine 95%;3-Pyridinamine,6-nitro-(9CI)
- CBNumber
- CB6412595
- Molecular Formula
- C5H5N3O2
- Formula Weight
- 139.11
- MOL File
- 14916-65-5.mol
5-AMINO-2-NITROPYRIDINE Property
- Melting point:
- 234-235 °C (decomp)(Solv: benzene (71-43-2))
- Boiling point:
- 382.9±22.0 °C(Predicted)
- Density
- 1.437±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- -1.02±0.10(Predicted)
- Appearance
- Yellow to brown Solid
Safety
- HS Code
- 2933599590
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- N901115
- Product name
- 6-Nitropyridin-3-amine
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- N901115
- Product name
- 6-Nitropyridin-3-amine
- Packaging
- 100mg
- Price
- $155
- Updated
- 2021/12/16
- Product number
- FA54375
- Product name
- 3-Amino-6-Nitropyridine
- Packaging
- 100mg
- Price
- $200
- Updated
- 2021/12/16
- Product number
- FA54375
- Product name
- 3-Amino-6-Nitropyridine
- Packaging
- 25mg
- Price
- $100
- Updated
- 2021/12/16
- Product number
- FA54375
- Product name
- 3-Amino-6-Nitropyridine
- Packaging
- 50mg
- Price
- $150
- Updated
- 2021/12/16
5-AMINO-2-NITROPYRIDINE Chemical Properties,Usage,Production
Uses
6-Nitropyridin-3-amine is used in preparation of dihydroquinazoline compounds as NAV1.8 inhibitors.
Synthesis
52092-47-4
14916-65-5
General procedure for the synthesis of 5-amino-2-nitropyridine from 2-nitro-5-chloropyridine: To a solution of 5-chloro-2-nitropyridine (3 g, 19 mmol) in ethanol (EtOH, 30 mL) was added saturated ammonia (NH3-H2O, 20 mL). The reaction mixture was placed in an autoclave and the reaction was stirred at 50 psi pressure and 150 °C overnight. The progress of the reaction was monitored by thin layer chromatography (TLC) and after confirming the completion of the reaction, the reaction mixture was cooled to room temperature. The resulting solid product was collected by filtration and washed with petroleum ether (PE, 100 mL) to afford 5-amino-2-nitropyridine (0.7 g, yield: 26%) as a yellow solid. Mass spectrometry (MS) analysis showed: m/z 140.1 ([M+H]+).
References
[1] Patent: WO2013/126608, 2013, A1. Location in patent: Paragraph 00647
5-AMINO-2-NITROPYRIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-AMINO-2-NITROPYRIDINE manufacturers
- Product
- 5-AMINO-2-NITROPYRIDINE 14916-65-5
- Price
- US $1.00-1.00/Kg/Drum
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 50tons
- Release date
- 2020-05-12
- Product
- 5-AMINO-2-NITROPYRIDINE 14916-65-5
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons min
- Release date
- 2021-09-08
- Product
- 5-AMINO-2-NITROPYRIDINE 14916-65-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2019-12-24