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5-AMINO-2-NITROPYRIDINE

Product Name
5-AMINO-2-NITROPYRIDINE
CAS No.
14916-65-5
Chemical Name
5-AMINO-2-NITROPYRIDINE
Synonyms
6-nitro-3-PyridinaMine;2-Nitro-5-pyridinamine;6-Nitropyridin-3-amine;3-Amino-6-nitropyridine;5-AMINO-2-NITROPYRIDINE;3-Pyridinamine, 6-nitro-;6-Nitro-pyridin-3-ylamine;5-Amino-2-nitropyridine95%;5-Amino-2-nitropyridine 95%;3-Pyridinamine,6-nitro-(9CI)
CBNumber
CB6412595
Molecular Formula
C5H5N3O2
Formula Weight
139.11
MOL File
14916-65-5.mol
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5-AMINO-2-NITROPYRIDINE Property

Melting point:
234-235 °C (decomp)(Solv: benzene (71-43-2))
Boiling point:
382.9±22.0 °C(Predicted)
Density 
1.437±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
-1.02±0.10(Predicted)
Appearance
Yellow to brown Solid
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Safety

HS Code 
2933599590
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TRC
Product number
N901115
Product name
6-Nitropyridin-3-amine
Packaging
10mg
Price
$45
Updated
2021/12/16
TRC
Product number
N901115
Product name
6-Nitropyridin-3-amine
Packaging
100mg
Price
$155
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA54375
Product name
3-Amino-6-Nitropyridine
Packaging
100mg
Price
$200
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA54375
Product name
3-Amino-6-Nitropyridine
Packaging
25mg
Price
$100
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA54375
Product name
3-Amino-6-Nitropyridine
Packaging
50mg
Price
$150
Updated
2021/12/16
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5-AMINO-2-NITROPYRIDINE Chemical Properties,Usage,Production

Uses

6-Nitropyridin-3-amine is used in preparation of dihydroquinazoline compounds as NAV1.8 inhibitors.

Synthesis

52092-47-4

14916-65-5

General procedure for the synthesis of 5-amino-2-nitropyridine from 2-nitro-5-chloropyridine: To a solution of 5-chloro-2-nitropyridine (3 g, 19 mmol) in ethanol (EtOH, 30 mL) was added saturated ammonia (NH3-H2O, 20 mL). The reaction mixture was placed in an autoclave and the reaction was stirred at 50 psi pressure and 150 °C overnight. The progress of the reaction was monitored by thin layer chromatography (TLC) and after confirming the completion of the reaction, the reaction mixture was cooled to room temperature. The resulting solid product was collected by filtration and washed with petroleum ether (PE, 100 mL) to afford 5-amino-2-nitropyridine (0.7 g, yield: 26%) as a yellow solid. Mass spectrometry (MS) analysis showed: m/z 140.1 ([M+H]+).

References

[1] Patent: WO2013/126608, 2013, A1. Location in patent: Paragraph 00647

5-AMINO-2-NITROPYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-AMINO-2-NITROPYRIDINE Suppliers

J & K SCIENTIFIC LTD.
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18210857532; 18210857532
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86-10-82849933
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jkinfo@jkchemical.com
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China
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Pure Chemistry Scientific Inc.
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001-857-928-2050 or 1-888-588-9418
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001-617-206-9595
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sales@chemreagents.com
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021-50135380
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China
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Nan Jing Dirise Chemcial Co.,LTD
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025-52161033 15312098939
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025-83254025
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sales@njdrschem.com
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China
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Jinan Trio PharmaTech Co., Ltd.
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+86 (531) 55696010 QQ 1762738062
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Record Tech (Shanghai) Co., LTD
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Bide Pharmatech Ltd.
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Synchem OHG
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+49 5662 408730
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+49 5662 4087320
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Germany
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Shanghai Worldyang Chemical Co.,Ltd.
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021-021-56795766
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+86-21-56795266
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sales@worldyachem.com
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China
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View Lastest Price from 5-AMINO-2-NITROPYRIDINE manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
5-AMINO-2-NITROPYRIDINE 14916-65-5
Price
US $1.00-1.00/Kg/Drum
Min. Order
1g
Purity
98%
Supply Ability
50tons
Release date
2020-05-12
Dideu Industries Group Limited
Product
5-AMINO-2-NITROPYRIDINE 14916-65-5
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons min
Release date
2021-09-08
Career Henan Chemical Co
Product
5-AMINO-2-NITROPYRIDINE 14916-65-5
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kg
Release date
2019-12-24

14916-65-5, 5-AMINO-2-NITROPYRIDINERelated Search:


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  • 5-Amino-2-nitropyridine 95%
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  • 5-Amino-2-nitropyridine95%
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