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Dehydroabietic acid

Product Name
Dehydroabietic acid
CAS No.
1740-19-8
Chemical Name
Dehydroabietic acid
Synonyms
Dehydroabietic;Dehydroabietate;(1R,4aS,10aR)-7-isopropyl-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1-carboxylic acid;Abieta-8,11,13-trien-18-oic acid;NSC 2952;[1R-(1α,4a;ehydroabieticaci;dehydro-abieticaci;DEHYDROABIETIC ACID;Ecabet Sodium Impurity 3
CBNumber
CB6424042
Molecular Formula
C20H28O2
Formula Weight
300.44
MOL File
1740-19-8.mol
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Dehydroabietic acid Property

Melting point:
174-176℃
Boiling point:
394.13°C (rough estimate)
Density 
1.058
refractive index 
1.5404 (estimate)
storage temp. 
Sealed in dry,Store in freezer, under -20°C
solubility 
DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 10 mg/ml
form 
A solid
pka
4.66±0.40(Predicted)
InChIKey
NFWKVWVWBFBAOV-UHFFFAOYSA-N
LogP
6.120 (est)
EPA Substance Registry System
Dehydroabietic acid (1740-19-8)
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Safety

Hazard Codes 
T,N
Risk Statements 
25-50
Safety Statements 
45-61
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
1
HS Code 
29161900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SMB00089
Product name
Dehydroabietic acid
Purity
≥95% (LC/MS-ELSD)
Packaging
1mg
Price
$318
Updated
2024/03/01
TRC
Product number
D229085
Product name
Dehydroabietic acid
Packaging
500mg
Price
$775
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
50583
Product name
Dehydroabietic acid
Packaging
100mg
Price
$650
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
RES0008661
Product name
(+)-DEHYDROABIETIC ACID
Purity
95.00%
Packaging
10MG
Price
$700.74
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD20963
Product name
Dehydroabietic acid
Packaging
10g
Price
$350
Updated
2021/12/16
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Dehydroabietic acid Chemical Properties,Usage,Production

Chemical Properties

White Solid or Colorless needle crystal, Slightly soluble in water, soluble in methanol, ethanol, DMSO and other organic solvents. It is an abietane diterpenic resin acid that is obtained from Pinus resin.

Uses

Dehydroabietic Acid is a resin acid found commonly in rosin. Dehydroabietic Acid is used in rosin-type nucleating agent for polypropylene (PP). Dehydroabietic Acid is used commonly in the synthesis of surfactants, antioxidants and chiral catalysts.

Definition

ChEBI: Dehydroabietic acid is an abietane diterpenoid that is abieta-8,11,13-triene substituted at position 18 by a carboxy group. It has a role as a metabolite and an allergen. It is an abietane diterpenoid, a monocarboxylic acid and a carbotricyclic compound. It derives from an abietic acid. It is a conjugate acid of a dehydroabietate.

Application

Dehydroabietic acid (DHA or DAA) is a bioactive phytochemical, diterpenoid found in various Pinus species. It is a resin acid and a derivative of abietic acid (AA).
Dehydroabietic acid has been used as a reference standard:
to study the aging process of Pinus resins using Fourier-transform infrared spectroscopy (FTIR)
to study the composition changes in Pinus genus with aging using Raman spectroscopy complemented with infrared spectroscopy
to estimate resistance against biotic stress as proxy in chemical defenses in Pinus halepensis

Biochem/physiol Actions

Dehydroabietic acid (DHA) exerts various biological activities such as anti-cancer, anti-aging, antimicrobial, antiulcer, gastroprotective, and cytotoxic activities. It is a potent anti-inflammatory agent and a dual activator of peroxisome proliferator-activated receptors alpha and gamma (PPAR α/γ). DHA has an anti-aging effect and a sirtuin 1 (SIRT1) activating compound. It has antibacterial properties against multidrug-resistant strains. dehydroabietic acid and its derivatives have gastroprotective and cytotoxic effects.

Dehydroabietic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Dehydroabietic acid manufacturers

airuikechemical co., ltd.
Product
dehydroabietic acid 1740-19-8
Price
US $0.00-0.00/Kg
Min. Order
1Kg
Purity
99.9%
Supply Ability
200tons
Release date
2024-04-09
Hebei Yanxi Chemical Co., Ltd.
Product
Dehydroabietic acid 1740-19-8
Price
US $50.00-43.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 tons
Release date
2023-09-27
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Dehydroabietic acid 1740-19-8
Price
US $1.00/KG
Min. Order
1KG
Purity
≥98.0%
Supply Ability
5tons/month
Release date
2021-06-21

1740-19-8, Dehydroabietic acidRelated Search:


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  • Abieta-8,11,13-trien-18-oic acid
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  • Ecabet Sodium Impurity 3
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  • 1740-19-8