Dehydroabietic acid

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Dehydroabietic acid

Product Name: Dehydroabietic acid
CAS No.: 1740-19-8
Chemical Name: Dehydroabietic acid
Synonyms: Dehydroabietic;Dehydroabietate;(1R,4aS,10aR)-7-isopropyl-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1-carboxylic acid;Abieta-8,11,13-trien-18-oic acid;NSC 2952;[1R-(1α,4a;ehydroabieticaci;dehydro-abieticaci;DEHYDROABIETIC ACID;Ecabet Sodium Impurity 3
CBNumber: CB6424042
Molecular Formula: C20H28O2
Formula Weight: 300.44
MOL File: 1740-19-8.mol

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Dehydroabietic acid Property

Melting point:: 174-176℃
Boiling point:: 394.13°C (rough estimate)
Density: 1.058
refractive index: 1.5404 (estimate)
storage temp.: Sealed in dry,Store in freezer, under -20°C
solubility: DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 10 mg/ml
form: A solid
pka: 4.66±0.40(Predicted)
color: White to yellow
InChIKey: NFWKVWVWBFBAOV-UHFFFAOYSA-N
LogP: 6.120 (est)
EPA Substance Registry System: Dehydroabietic acid (1740-19-8)

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Safety

Hazard Codes: T,N
Risk Statements: 25-50
Safety Statements: 45-61
RIDADR: UN 2811 6.1 / PGIII
WGK Germany: 1
HS Code: 29161900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SMB00089
Product name: Dehydroabietic acid
Purity: ≥95% (LC/MS-ELSD)
Packaging: 1mg
Price: $318
Updated: 2024/03/01

TRC

Product number: D229085
Product name: Dehydroabietic acid
Packaging: 500mg
Price: $775
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 50583
Product name: Dehydroabietic acid
Packaging: 100mg
Price: $650
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: RES0008661
Product name: (+)-DEHYDROABIETIC ACID
Purity: 95.00%
Packaging: 10MG
Price: $700.74
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD20963
Product name: Dehydroabietic acid
Packaging: 10g
Price: $350
Updated: 2021/12/16

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Dehydroabietic acid Chemical Properties,Usage,Production

Chemical Properties

White Solid or Colorless needle crystal, Slightly soluble in water, soluble in methanol, ethanol, DMSO and other organic solvents. It is an abietane diterpenic resin acid that is obtained from Pinus resin.

Uses

Dehydroabietic Acid is a resin acid found commonly in rosin. Dehydroabietic Acid is used in rosin-type nucleating agent for polypropylene (PP). Dehydroabietic Acid is used commonly in the synthesis of surfactants, antioxidants and chiral catalysts.

Definition

ChEBI: Dehydroabietic acid is an abietane diterpenoid that is abieta-8,11,13-triene substituted at position 18 by a carboxy group. It has a role as a metabolite and an allergen. It is an abietane diterpenoid, a monocarboxylic acid and a carbotricyclic compound. It derives from an abietic acid. It is a conjugate acid of a dehydroabietate.

Application

Dehydroabietic acid (DHA or DAA) is a bioactive phytochemical, diterpenoid found in various Pinus species. It is a resin acid and a derivative of abietic acid (AA).
Dehydroabietic acid has been used as a reference standard:
to study the aging process of Pinus resins using Fourier-transform infrared spectroscopy (FTIR)
to study the composition changes in Pinus genus with aging using Raman spectroscopy complemented with infrared spectroscopy
to estimate resistance against biotic stress as proxy in chemical defenses in Pinus halepensis

Biochem/physiol Actions

Dehydroabietic acid (DHA) exerts various biological activities such as anti-cancer, anti-aging, antimicrobial, antiulcer, gastroprotective, and cytotoxic activities. It is a potent anti-inflammatory agent and a dual activator of peroxisome proliferator-activated receptors alpha and gamma (PPAR α/γ). DHA has an anti-aging effect and a sirtuin 1 (SIRT1) activating compound. It has antibacterial properties against multidrug-resistant strains. dehydroabietic acid and its derivatives have gastroprotective and cytotoxic effects.

Dehydroabietic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Dehydroabietic acid manufacturers

Hebei Mujin Biotechnology Co.,Ltd

Product: Dehydroabietic acid 1740-19-8
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2023-09-25

Hebei Zhuanglai Chemical Trading Co Ltd

Product: Dehydroabietic acid 1740-19-8
Price: US $45.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 tons
Release date: 2024-12-24

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Dehydroabietic acid 1740-19-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: ≥98.0%
Supply Ability: 5tons/month
Release date: 2021-06-21

1740-19-8, Dehydroabietic acidRelated Search:

Ecabet sodium DARUTOSIDE DARUTIGENOL Rosin Amine Lercanidipine bamboo flavone DL-Malic acid ABIETIC ACID Dehydroabietic acid methyl Ecabet (+)-Dehydroabietic acid Dehydroabietic acid DEHYDROABIETIC ACID-6,6-D2 [1S,(+)]-1,2,3,4,4a,9,10,10aα-Octahydro-6-hydroxy-1,4aβ-dimethyl-7-(1-methylethyl)-1β-phenanthrenecarboxylic acid 7-oxodehydroabietic acid 7-OXOMETHYLDEHYDROABIETATE METHYL (1R,4AS)-9-(ACETYLOXY)-7-ISOPROPYL-1,4A-DIMETHYL-1,2,3,4,4A,9,10,10A-OCTAHYDRO-1-PHENANTHRENECARBOXYLATE (1R,4AS)-7-ISOPROPYL-1,4A-DIMETHYL-1,2,3,4,4A,9,10,10A-OCTAHYDROPHENANTHRENE-1-CARBOXYLIC ACID Dehydroabietic

[1theta-(1alpha,4abeta,10aalpha)]--methylethyl)

13-isopropylpodocarpa-8,11,13-trien-15-oicacid

13-trien-15-oicacid,13-isopropyl-podocarpa-11

1-phenanthrenecarboxylicacid,1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1

dehydro-abieticaci

DEHYDROABIETIC ACID

1-Phenanthrenecarboxylicacid, 1,2,3,4,4a,9,10,10a-octahydro-1,4a-diMethyl-7-(1-Methylethyl)-,(1R,4aS,10aR)-

[1R-(1alpha,4abeta,10aalpha)]-1,2,3,4,4a,9,10,10a-octahydro-7-isopropyl-1,4a-dimethylphenanthren-1-carboxylic acid

PODOCARPA-8,11,13-TRIEN-15-OICACID,13-ISOPROPYL-

Kolophonium, disproportioniert, dehydriert, hydriert oder dimerisiert (polymerisiert)

1-PHENANTHRENECARBOXYLICACID,1,2,

(1R,4aS,10aR)-1,2,3,4,4a,9,10,10a-Octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenecarboxylic acid

(1R)-1,4aβ-Dimethyl-7-isopropyl-1,2,3,4,4a,9,10,10aα-octahydrophenanthrene-1α-carboxylic acid

13-Isopropylpodocarpa-8,11,13-trien-18-oic acid

8,11,13-Abietatriene-18-oic acid

Abieta-8(14),9(11),12-triene-18-oic acid

Abieta-8,11,13-trien-18-oic acid

[1R-(1α,4a

NSC 2952

abieta-8(14),9(11),12-trien-18-oic acid

[1R-(1α,4aβ,10aα)]-1,2,3,4,4a,9,10,10a-octahydro-7-isopropyl-1,4a-dimethylphenanthren-1-carboxylic acid

Dehydroabietate

(1R,4aS,10aR)-7-isopropyl-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1-carboxylic acid

Ecabet Sodium Impurity 3

ehydroabieticaci

(1R,4aS,10aR)-7-Isopropyl-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1-carboxylic acidahydrophenanthrene-1-carboxylic acid

Dehydroabietic

[1R-(1α,4aβ,10aα)]-1,2,3,4,4a,9,10,10a-octahydro-7-isopro...

Dehydroabietic acid (Purified) in methanol

Dehydroabietic acid, 10 mM in DMSO

1740-19-8