ChemicalBook > CAS DataBase List > Propantheline bromide

Propantheline bromide

Product Name
Propantheline bromide
CAS No.
50-34-0
Chemical Name
Propantheline bromide
Synonyms
pantas;sc-3171;ketaman;kivatin;ercorax;pervagal;ercotina;propantel;Corrigast;prodixamon
CBNumber
CB6444482
Molecular Formula
C23H30BrNO3
Formula Weight
448.39
MOL File
50-34-0.mol
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Propantheline bromide Property

Melting point:
159-161°C
Density 
1.2916 (rough estimate)
refractive index 
1.6200 (estimate)
storage temp. 
2-8°C
solubility 
H2O: soluble50mg/mL
form 
powder
color 
white to off-white
Water Solubility 
>=10 g/100 mL at 21 ºC
Stability:
Stable. Combustible. Incompatible with strong oxidizing agents.
EPA Substance Registry System
Propantheline bromide (50-34-0)
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Safety

Hazard Codes 
Xn
Risk Statements 
22
Safety Statements 
36
WGK Germany 
3
RTECS 
BP8249200
HS Code 
2932992000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
P8891
Product name
Propantheline bromide
Purity
≥97% (TLC), powder
Packaging
5g
Price
$56.6
Updated
2024/03/01
Sigma-Aldrich
Product number
1570508
Product name
Propantheline bromide
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
200mg
Price
$412
Updated
2024/03/01
Cayman Chemical
Product number
23609
Product name
Propantheline (bromide)
Purity
≥95%
Packaging
500mg
Price
$26
Updated
2024/03/01
Cayman Chemical
Product number
23609
Product name
Propantheline (bromide)
Purity
≥95%
Packaging
1g
Price
$43
Updated
2024/03/01
Sigma-Aldrich
Product number
PHR1575
Product name
Propantheline bromide
Purity
Pharmaceutical Secondary Standard; Certified Reference Material
Packaging
500mg
Price
$173
Updated
2024/03/01
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Propantheline bromide Chemical Properties,Usage,Production

Chemical Properties

white crystalline powder

Uses

Propantheline is an antimuscarinic agent used in the treatment of hyperhidrosis (excessive sweating), enuresis (involuntary urination) as well as cramps or spasms of the stomach, intestine and bladder.

Uses

anticholinergic

Uses

A muscarinic acetylcholine receptor antagonist

Definition

ChEBI: Propantheline bromide is a member of xanthenes.

brand name

Pro-Banthine (Searle).

General Description

Propantheline bromide,2-hydroxy-ethyl)diisopropylmethylammonium bromidexanthene-9-carboxylate (Pro-Banthine), is prepared in amanner exactly analogous to that used for methanthelinebromide. It is a white, water-soluble, crystalline substance,with properties quite similar to those of methantheline bromide.Its chief difference from methantheline bromide is inits potency, which has been estimated variously to be 2 to5 times as great.

General Description

White crystals or white powder. Melting point 159-161°C .Used therapeutically as an anticholinergic.

Air & Water Reactions

Water soluble.

Health Hazard

SYMPTOMS: Symptoms of exposure to Propantheline bromide include dilated pupils and blurred vision; increased intraocular tension and heart rate; hot, dry, red skin; dry mouth; disorientation; hallucinations; aggressive behavior; rapid pulse and respiration; convulsions; and coma.

Fire Hazard

Flash point data are not available for Propantheline bromide , but Propantheline bromide is probably combustible.

Biochem/physiol Actions

Inhibits action of acetylcholine at post-ganglionic synapses; muscarinic acetylcholine receptor antagonist; antispasmodic; reduces gastric acid secretion.

Veterinary Drugs and Treatments

In small animal medicine propantheline bromide has been used for its antispasmodic/antisecretory effects in the treatment of diarrhea. It is also employed in the treatment of hyperreflexic detrusor or urge incontinence and as oral treatment in anticholinergic responsive bradycardias. In horses, propantheline has been used intravenously to reduce colonic peristalsis and for relaxing the rectum to allow easier rectal examination and surgery.

Propantheline bromide Preparation Products And Raw materials

Raw materials

Preparation Products

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Propantheline bromide Suppliers

SIGMA-RBI
Tel
--
Fax
--
Country
Switzerland
ProdList
6896
Advantage
91
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View Lastest Price from Propantheline bromide manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
Propantheline bromide 50-34-0
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2021-09-09
Hebei Mojin Biotechnology Co., Ltd
Product
Propantheline bromide 50-34-0
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-08-29
Zhuozhou Wenxi import and Export Co., Ltd
Product
Propantheline bromide 50-34-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10

50-34-0, Propantheline bromide Related Search:


  • nci-c56257
  • neometantyl
  • neopepulsan
  • pantas
  • pantheline
  • pervagal
  • Probanthine
  • pro-banthine
  • prodixamon
  • pro-gastron
  • propantel
  • sc-3171
  • xanthene-9-carboxylicacid,esterwith(2-hydroxyethyl)diisopropylmethylammon
  • [2-HYDROXYETHYL]DIISOPROPYLMETHYL-AMMONIUM BROMIDE XANTHENE-9-CARBOXYLATE
  • ercotina
  • iumbromide
  • ketaman
  • kivatin
  • PROPANTHELINE BROMIDE
  • methyl-[2-[oxo(9H-xanthen-9-yl)methoxy]ethyl]-di(propan-2-yl)ammonium bromide
  • diisopropyl(methyl)(2-xanthen-9-ylcarbonyloxyethyl)ammonium bromide
  • propanthine
  • 2-Propanaminium, N-methyl-N-(1-methylethyl)-N-2-(9H-xanthen-9-ylcarbonyl)oxyethyl-, bromide
  • PROPANTHELINEBROMIDE,USP
  • b-Diisopropylaminoethyl xanthene-9-carboxylate methobromide
  • Propantheline bronmide
  • Propantheline bromide,(2-Hydroxyethyl)diisopropylmethylammonium bromide xanthene-9-carboxylate
  • Propantheline Bromide (200 mg)
  • ammonium,diisopropyl(2-hydroxyethyl)methyl-,bromide,xanthene-9-carboxylate
  • diisopropyl(2-hydroxyethyl)methylammoniumbromidexanthene-9-carboxylate
  • ercorax
  • Corrigast
  • N-Methyl-N-(1-Methylethyl)-N-[2-[(9H-xanthen-9-ylcarbonyl)oxy]ethyl]-2-propanaMiniuM BroMide
  • N-(2-((9H-xanthene-9-carbonyl)oxy)ethyl)-N-isopropyl-N-methylpropan-2-aminium bromide
  • Propantheline bromide USP/EP/BP
  • Propantheline bromide,50-34-0
  • Propantheline Bromide (1570508)
  • Neopepulsan|||Pro-Banthine|||Neometantyl
  • Bromopropylamine hydrochloride
  • 50-34-0
  • 50-34-1
  • C23H30BrNO3
  • C23H31BrNO3
  • PROBANTHINE
  • Drug bulk
  • Miscellaneous
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals