ChemicalBook > CAS DataBase List > S(-)-BAY K 8644

S(-)-BAY K 8644

Product Name
S(-)-BAY K 8644
CAS No.
98625-26-4
Chemical Name
S(-)-BAY K 8644
Synonyms
R-5417;BAY-r-5417;S(-)-BAY K 8644;Bay-K-8644 ((S)-(-)-);S(-)-BAY K 8644 CA2+ CHANNEL ACTIVATO;Bay-K-8644 (S)-(-)-[(S)-(-)-Bay-K-8644;Ca channels,Inhibitor,(S) ( ) Bay K 8644,inhibit,(S)()BayK8644,Calcium Channel,Ca2+ channels;methyl (-)-1,4-dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]pyridine-3-carboxylate;Methyl (S)-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-1,4-dihydropyridine-3-carboxylate;(4S)-1,4-Dihydro-2,6-dimethyl-5-nitro-4-(2-trifluoromethyl)phenyl)-3-pyridinecarboxylicacidmethylester
CBNumber
CB6448884
Molecular Formula
C16H15F3N2O4
Formula Weight
356.3
MOL File
98625-26-4.mol
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S(-)-BAY K 8644 Property

storage temp. 
2-8°C
solubility 
H2O: slightly soluble
form 
solid
color 
yellow
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Safety

Hazard Codes 
Xi
Risk Statements 
36/38
Safety Statements 
26-36
WGK Germany 
3
HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
B133
Product name
(S)-(?)-Bay K8644
Purity
≥98% (HPLC), solid
Packaging
1mg
Price
$229
Updated
2024/03/01
Sigma-Aldrich
Product number
B133
Product name
(S)-(?)-Bay K8644
Purity
≥98% (HPLC), solid
Packaging
5mg
Price
$905
Updated
2024/03/01
Cayman Chemical
Product number
19988
Product name
(S)-(?)-Bay K8644
Purity
≥98%
Packaging
500μg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
19988
Product name
(S)-(?)-Bay K8644
Purity
≥98%
Packaging
1mg
Price
$61
Updated
2024/03/01
Cayman Chemical
Product number
19988
Product name
(S)-(?)-Bay K8644
Purity
≥98%
Packaging
5mg
Price
$214
Updated
2024/03/01
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S(-)-BAY K 8644 Chemical Properties,Usage,Production

Uses

(S)-(-)-Bay K8644 has been used as a L-type calcium channel (LTCC) agonist in the suprachiasmatic nucleus (SCN) slices. It has also been used as a LTCC agonist to induce arrhythmia?in rats.

Definition

ChEBI: (S)-Bay-K-8644 is a methyl 2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3-carboxylate in which the 4-position has (S)-configuration. It is an enantiomer of a (R)-Bay-K-8644.

General Description

(S)-(-)-Bay K8644, a dihydropyridine compound is a Ca2+?channel activator. It is an enantiomer of Bay K 8644.

Biological Activity

L-type Ca 2+ -channel activator with positive inotropic, vasoconstrictive and behavioral effects in vivo . Enantiomer of (1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-3-pyridinecarboxylic acid, methyl ester ).

Biochem/physiol Actions

(S)-(-)-Bay K8644 enhances Ca2+ current, whereas the (+)-Bay K 8644 is a weak Ca2+ channel antagonist. Bay K 8644 is lipophilic and it effectively scavenges superoxide anions.

storage

Store at +4°C

S(-)-BAY K 8644 Preparation Products And Raw materials

Raw materials

Preparation Products

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S(-)-BAY K 8644 Suppliers

China 40 Germany 2 India 1 Switzerland 1 United Kingdom 1 United States 11 Global 56

98625-26-4, S(-)-BAY K 8644Related Search:

3-[o-(alpha,alpha,alpha-trifluorotolyl)]propionic acid 2-methyl-1-nitropropane Phenibut BAY K-8644 (+/-),(+/-)-BAY K 8644,(RS)-BAY K 8644,(+/-)-BAY K8644 CALCIUM SLOW CHANNEL 3-[(2-TRIFLUOROMETHYL)PHENYL]-1-PROPENE 3-(2-TRIFLUOROMETHYL-PHENYL)-PROPAN-1-OL 1-NITRO-2-METHYL-BUTANE o-(trifluoromethyl)phenethylamine METHYL (R)-3-PHENYLBUTYRATE S(-)-BAY K 8644 4-AMINO-3-PHENYL-1-BUTANOL 3-(2-TRIFLUOROMETHYL-PHENYL)-PROPIONALDEHYDE METHYL 4-NITROBUTYRATE BETA-(NITROMETHYL)-BENZENEPROPANOIC ACID R(+)-BAY K 8644 CA2(+) CHANNEL BLOCKE,(+/-)-BAY K 8644, 0 TO 5 °C,R(+)-BAY K 8644 98% 0 C,R(+)-BAY K 8644 BAY K-8644 (+/-),(+/-)-BAY K 8644 (+/-) CAGED BAY K 8644 R(+)-BAY K 8644, CALCIUM CHANNEL

  • S(-)-BAY K 8644
  • (4S)-1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-[(2-TRIFLUOROMETHYL)PHENYL]-3-PYRIDINECARBOXYLIC ACID METHYL ESTER
  • S(-)-BAY K 8644 CA2+ CHANNEL ACTIVATO
  • (4S)-1,4-Dihydro-2,6-dimethyl-5-nitro-4-(2-trifluoromethyl)phenyl)-3-pyridinecarboxylicacidmethylester
  • s-(-)-1,4-dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-3-pyridinecarboxylic acid methyl ester
  • [4S,(-)]-1,4-Dihydro-2,6-dimethyl-5-nitro-4-(2-trifluoromethylphenyl)pyridine-3-carboxylic acid methyl ester
  • BAY-r-5417
  • R-5417
  • Bay-K-8644 ((S)-(-)-)
  • methyl (-)-1,4-dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]pyridine-3-carboxylate
  • 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-, methyl ester, (4S)-
  • Bay-K-8644 (S)-(-)-[(S)-(-)-Bay-K-8644
  • Ca channels,Inhibitor,(S) ( ) Bay K 8644,inhibit,(S)()BayK8644,Calcium Channel,Ca2+ channels
  • Methyl (S)-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-1,4-dihydropyridine-3-carboxylate
  • 98625-26-4
  • C16H15F3N2O4
  • BioChemical
  • Cell Signaling and Neuroscience
  • Cell Biology
  • Calcium Channel Modulators
  • Inhibitors and Activators
  • Ion Channels
  • Voltage-gated Ion Channels
  • Calcium channel