Tilmicosin
Brief introduction Chemical Properties Uses- Product Name
- Tilmicosin
- CAS No.
- 108050-54-0
- Chemical Name
- Tilmicosin
- Synonyms
- Timicosin;Tilmicosine;pulmotil;Dianthi Herba;EL 870;Stmicco;Micotil;LY 177370;Timicoxin;TILMICOSIN
- CBNumber
- CB6463168
- Molecular Formula
- C46H80N2O13
- Formula Weight
- 869.15
- MOL File
- 108050-54-0.mol
Tilmicosin Property
- Melting point:
- >97°C (dec.)
- alpha
- D23 +12.75° (c = 0.010004 in CHCl3, 5 cm)
- Boiling point:
- 926.6±65.0 °C(Predicted)
- Density
- 1.18±0.1 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- solubility
- Acetone (Slightly), DMSO (Slightly), Methanol (Sparingly)
- pka
- pKa (66% DMF): 7.4, 8.5(at 25℃)
- color
- White to Off-White
- InChIKey
- JTSDBFGMPLKDCD-XVFHVFLVSA-N
- EPA Substance Registry System
- Tilmicosin (108050-54-0)
Safety
- WGK Germany
- 3
- HS Code
- 29419090
- Hazardous Substances Data
- 108050-54-0(Hazardous Substances Data)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- 33864
- Product name
- Tilmicosin
- Purity
- VETRANAL?, analytical standard, mix of isomers
- Packaging
- 100mg
- Price
- $119
- Updated
- 2024/03/01
- Product number
- 1667370
- Product name
- Tilmicosin
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 250mg
- Price
- $436
- Updated
- 2024/03/01
- Product number
- 257406
- Product name
- Tilmicosin
- Packaging
- 500mg
- Price
- $531
- Updated
- 2021/12/16
- Product number
- T440500
- Product name
- Tilmicosin,85%
- Packaging
- 50mg
- Price
- $70
- Updated
- 2021/12/16
- Product number
- A574
- Product name
- Tilmicosin,mixtureofisomers
- Packaging
- 1g
- Price
- $312
- Updated
- 2021/12/16
Tilmicosin Chemical Properties,Usage,Production
Brief introduction
Tilmicosin is a relatively novel semi-synthetic macrolide antibiotics derived from tylosin for being applied to livestock and poultry. The chemical name is 4A-O-de (2, 6-dideoxy-methyl-3-C--L-ribose-pyran-hexyl)-20-deoxy-20-(3,5-dimethyl-1-piperidinyl)-[20 (cis: trans)] tylosin. Molecule formula is C46H80N2O13 and the molecular weight of 869.15.
Tilmicosin has a similar antibacterial spectrum as tylosin but has enhanced effect on the anti-Pasteurella multocida and hemolytic pasteurella. It was successfully developed in 1980s and initially used with a code of EL-870. Common trade names include Pulmotil © Micotil ©, preparations include tilmicosin soluble powder, premix (20%) preparation, and injection. In 1990 it was approved in most European countries; it was approved in the US in 1992, and included in USP. China also has some domestic enterprises approved for production of tilmicosin.
Because of its special antibacterial activity and pharmacokinetic characteristics, the drug has been approved for clinical prevention and treatment of infectious diseases for cattle, goats, sheep, cows, pigs, and chickens. It is especially applied to the treatment of respiratory diseases of livestock, such as cattle Actinobacillus pleuropneumonia, Pasteurella disease, chicken mycoplasmosis and mastitis of lactating animals.
The above information is edited by the Chemicalbook of Dai Xiongfeng.
Chemical Properties
It is white or white powder with humidity: ≤5.0%.
Uses
It can be used as anti-bacterial.
It is mainly used for the treatment of infection caused by pleuropneumonia, Actinobacillus, Pasteurella and mycoplasma.
Chemical Properties
White Solid
Uses
Tilmicosin is a semi-synthetic antibiotic derived from desmycosin (tylosin B), a minor co-metabolite of tylosin. Tilmicosin is produced by reductive amination of desmycosin. Desmycosin itself is prepared by the partial hydrolysis of tylosin with the loss of the mycarosyl sugar. The piperidinyl group at C20 of tilmicosin provides a wider spectrum of antibiotic action, in particular good protection against Pasteurella in livestock.
Uses
A Macrolide antibiotic.
Uses
Macrolide antibiotic structurally related to tylosin. Antibacterial
Veterinary Drugs and Treatments
Tilmicosin is indicated for the treatment of bovine or ovine respiratory diseases (BRD) caused by Mannheimia (Pasturella) haemolytica.
Tilmicosin Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Tilmicosin manufacturers
- Product
- Tilmicosin 108050-54-0
- Price
- US $0.00/kg
- Min. Order
- 25kg
- Purity
- ＞85%
- Supply Ability
- 10tons
- Release date
- 2024-04-24
- Product
- Tilmicosin 108050-54-0
- Price
- US $150.00/KG
- Min. Order
- 1KG
- Purity
- 0.99
- Supply Ability
- 30T
- Release date
- 2023-10-25
- Product
- Tilmicosin 108050-54-0
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 85%
- Supply Ability
- 1000kg
- Release date
- 2022-11-22