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Tilorone dihydrochloride

Product Name
Tilorone dihydrochloride
CAS No.
27591-69-1
Chemical Name
Tilorone dihydrochloride
Synonyms
Flu;Deae-f;nsc-143969;Rmi 10008da;TILORONE 2HCL;Tilorone DiHCl;TILORONE HYDROCHLORIDE;Tilolone hydrochloride;2,7-Bis-deae-fluorenone;TILORONE DIHYDROCHLORIDE
CBNumber
CB6144470
Molecular Formula
C25H36Cl2N2O3
Formula Weight
483.47
MOL File
27591-69-1.mol
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Tilorone dihydrochloride Property

Melting point:
230-233 °C(lit.)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Methanol (Slightly)
form 
Solid
color 
Orange
Merck 
14,9440
InChIKey
BSVYJQAWONIOOU-UHFFFAOYSA-N
CAS DataBase Reference
27591-69-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22-36/37/38-40
Safety Statements 
7-22-26-37/39
WGK Germany 
3
RTECS 
LL9000000
HS Code 
2922.39.4500
Toxicity
LD50 in mice, rats (single dose): 959, 852 mg/kg orally; 145, 244 mg/kg i.p. (Krueger, Mayer)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H351Suspected of causing cancer

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
220957
Product name
Tilorone dihydrochloride
Purity
95%
Packaging
100mg
Price
$175
Updated
2024/03/01
TCI Chemical
Product number
T2836
Product name
Tilorone Dihydrochloride
Purity
>98.0%(HPLC)(T)
Packaging
100mg
Price
$97
Updated
2024/03/01
TCI Chemical
Product number
T2836
Product name
Tilorone Dihydrochloride
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$391
Updated
2024/03/01
Cayman Chemical
Product number
17868
Product name
Tilorone (hydrochloride)
Purity
≥98%
Packaging
50mg
Price
$37
Updated
2024/03/01
Cayman Chemical
Product number
17868
Product name
Tilorone (hydrochloride)
Purity
≥98%
Packaging
1g
Price
$353
Updated
2024/03/01
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Tilorone dihydrochloride Chemical Properties,Usage,Production

Description

Tilorone is an orally active, antiviral compound that induces interferon production and is reported to have antitumor, anti-inflammatory, and neuroprotective actions. With chronic administration, tilorone induces lysosomal glycosaminoglycan storage, rendering glycosaminoglycans resistant to enzymatic degradation.

Chemical Properties

Orange-yellow crystalline powder

Uses

Tilorone dihydrochloride is an orally active, interferon-inducing antiviral agent.

Uses

Tilorone dihydrochloride was used to study the interaction of drugs with synthetic self-complementary DNA by SPR (Surface Plasmon Resonance).

Definition

ChEBI: Tilorone dihydrochloride is the dihydrochloride salt of tilorone. It is used as an antiviral drug to treat influenza, herpes infection, viral hepatitis, acute respiratory viral infections and SARS. It has a role as an anti-inflammatory agent, an antineoplastic agent, an interferon inducer, a nicotinic acetylcholine receptor agonist and an antiviral drug. It contains a tilorone(2+).

brand name

Tilorone is INN.

General Description

Effect of tilorone dihydrochloride on the changes of transmembrane potential of mitochondrial membranes of the isolated rat hepatocytes has been investigated. Tilorone dihydrochloride is an orally active, interferon-inducing antiviral agent.

Tilorone dihydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Tilorone dihydrochloride Suppliers

Suzhou ChemWe Chemical Co., Ltd.
Tel
512-62706911 13401923197
Fax
0512-62706910
Email
sales@chemwe.com
Country
China
ProdList
94
Advantage
56
Mascot I.E. Co., Ltd
Tel
0519-85010339 13584504415
Fax
0519-85010366
Email
info@mascot-ie.com
Country
China
ProdList
190
Advantage
58
Jinan zhongdaoanran chemical Co;Ltd
Tel
18678233466 18678233466
Email
122574856@qq.com
Country
China
ProdList
102
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chembest Research Laboratories Limited
Tel
021-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6011
Advantage
61
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10194
Advantage
62
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9816
Advantage
59
EnciPharmatech Co., Ltd
Tel
025-52714267-66 13813902930
Fax
86 025 52714266
Email
stephen_shengll@hotmail.com
Country
China
ProdList
232
Advantage
64
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View Lastest Price from Tilorone dihydrochloride manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Tilorone dihydrochloride 27591-69-1
Price
US $0.00/KG
Min. Order
1KG
Purity
99%,USP
Supply Ability
500kg/month
Release date
2021-07-23
Henan Aochuang Chemical Co.,Ltd.
Product
Tilorone dihydrochloride 27591-69-1
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-16
Dideu Industries Group Limited
Product
Tilorone dihydrochloride 27591-69-1
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons Min
Release date
2021-07-15

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