ChemicalBook > CAS DataBase List > Tilorone dihydrochloride

Tilorone dihydrochloride

Product Name
Tilorone dihydrochloride
CAS No.
27591-69-1
Chemical Name
Tilorone dihydrochloride
Synonyms
Flu;Deae-f;nsc-143969;Rmi 10008da;TILORONE 2HCL;Tilorone DiHCl;TILORONE HYDROCHLORIDE;Tilolone hydrochloride;2,7-Bis-deae-fluorenone;TILORONE DIHYDROCHLORIDE
CBNumber
CB6144470
Molecular Formula
C25H36Cl2N2O3
Formula Weight
483.47
MOL File
27591-69-1.mol
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Tilorone dihydrochloride Property

Melting point:
230-233 °C(lit.)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Methanol (Slightly)
form 
Solid
color 
Orange
Merck 
14,9440
InChIKey
BSVYJQAWONIOOU-UHFFFAOYSA-N
CAS DataBase Reference
27591-69-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22-36/37/38-40
Safety Statements 
7-22-26-37/39
WGK Germany 
3
RTECS 
LL9000000
HS Code 
2922.39.4500
Toxicity
LD50 in mice, rats (single dose): 959, 852 mg/kg orally; 145, 244 mg/kg i.p. (Krueger, Mayer)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H351Suspected of causing cancer

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
220957
Product name
Tilorone dihydrochloride
Purity
95%
Packaging
100mg
Price
$175
Updated
2024/03/01
TCI Chemical
Product number
T2836
Product name
Tilorone Dihydrochloride
Purity
>98.0%(HPLC)(T)
Packaging
100mg
Price
$97
Updated
2024/03/01
TCI Chemical
Product number
T2836
Product name
Tilorone Dihydrochloride
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$391
Updated
2024/03/01
Cayman Chemical
Product number
17868
Product name
Tilorone (hydrochloride)
Purity
≥98%
Packaging
50mg
Price
$37
Updated
2024/03/01
Cayman Chemical
Product number
17868
Product name
Tilorone (hydrochloride)
Purity
≥98%
Packaging
1g
Price
$353
Updated
2024/03/01
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Tilorone dihydrochloride Chemical Properties,Usage,Production

Description

Tilorone is an orally active, antiviral compound that induces interferon production and is reported to have antitumor, anti-inflammatory, and neuroprotective actions. With chronic administration, tilorone induces lysosomal glycosaminoglycan storage, rendering glycosaminoglycans resistant to enzymatic degradation.

Chemical Properties

Orange-yellow crystalline powder

Uses

Tilorone dihydrochloride is an orally active, interferon-inducing antiviral agent.

Uses

Tilorone dihydrochloride was used to study the interaction of drugs with synthetic self-complementary DNA by SPR (Surface Plasmon Resonance).

Definition

ChEBI: Tilorone dihydrochloride is the dihydrochloride salt of tilorone. It is used as an antiviral drug to treat influenza, herpes infection, viral hepatitis, acute respiratory viral infections and SARS. It has a role as an anti-inflammatory agent, an antineoplastic agent, an interferon inducer, a nicotinic acetylcholine receptor agonist and an antiviral drug. It contains a tilorone(2+).

brand name

Tilorone is INN.

General Description

Effect of tilorone dihydrochloride on the changes of transmembrane potential of mitochondrial membranes of the isolated rat hepatocytes has been investigated. Tilorone dihydrochloride is an orally active, interferon-inducing antiviral agent.

Tilorone dihydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Tilorone dihydrochloride manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Tilorone dihydrochloride 27591-69-1
Price
US $0.01-1.00/KG
Min. Order
1KG
Purity
99%min
Supply Ability
20 tons
Release date
2020-05-08
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Tilorone dihydrochloride 27591-69-1
Price
US $0.00/KG
Min. Order
1KG
Purity
99%,USP
Supply Ability
500kg/month
Release date
2021-07-23
Henan Aochuang Chemical Co.,Ltd.
Product
Tilorone dihydrochloride 27591-69-1
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-16

27591-69-1, Tilorone dihydrochlorideRelated Search:

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  • 27591-69-1
  • C25H35ClN2O3
  • C25H36N2O3Cl2
  • C25H36Cl2N2O3
  • C25H36O3N22HCl
  • C25H34N2O32HCl
  • Building Blocks
  • Carbonyl Compounds
  • C15 to C38
  • Ketones
  • Organic Building Blocks
  • C15 to C38
  • Carbonyl Compounds
  • Chemical Synthesis
  • Ketones
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  • strong recommend
  • Fluorene series
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