Description References Description Background
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Elcatonin

Description References Description Background
Product Name
Elcatonin
CAS No.
60731-46-6
Chemical Name
Elcatonin
Synonyms
hc-58;ELCATONIN;Elcatonin RS;29-l-alanine-;ELCATONIN (EEL);CARBOCALCITONIN;Elcatonin Acetate;ELCATONIN, 98.0+%;Elcatonin USP/EP/BP;CARBACALCITONIN (EEL)
CBNumber
CB6478388
Molecular Formula
C148H244N42O47
Formula Weight
3363.83
MOL File
60731-46-6.mol
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Elcatonin Property

Density 
1.49±0.1 g/cm3(Predicted)
RTECS 
HS9270000
storage temp. 
-15°C
Sequence
H-Ser-Asn-Leu-Ser-Thr-Asu-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asp-Val-Gly-Ala-Gly-Thr-Pro-OH?(Ser-Asu Lacton)
InChIKey
DDPFHDCZUJFNAT-KDIBENGQNA-N
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological
Product number
E2235-70
Product name
Elcatonin
Packaging
200ug
Price
$462
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0019085
Product name
ELCATONIN ACETATE
Purity
95.00%
Packaging
5MG
Price
$498.47
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0024694
Product name
ELCATONIN
Purity
95.00%
Packaging
0.5MG
Price
$687.23
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0024694
Product name
ELCATONIN
Purity
95.00%
Packaging
1MG
Price
$782.23
Updated
2021/12/16
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Elcatonin Chemical Properties,Usage,Production

Description

Elcatonin (molecular formula: C148H244N42O47) is a kind of single, non-glycosylated polypeptide chain consisting of 31 amino acids. It is a calcitonin derivative, and is used as an anti-parathyroid agent. It is mainly used for remitting and eliminating the pain induced by Osteoporosis. It has several physiological effects including: (1) inhibit the absorption and autolysis of bones, thus leading to the reduction of the blood calcium level; (2) inhibit the dissolving and transferring of bone salts, further promoting the excretion of calcium and phosphorus in urine; (3) it inhibits the process of calcium, phosphorus and sodium re-absorption by renal tubules.

References

http://www.prospecbio.com/Elcatonin_7_42/
https://en.wikipedia.org/wiki/Elcatonin

Uses

Osteoporosis; Hypercalcemia; Paget’s disease

Hazard

A poison by ingestion.

Safety Profile

experimental neoplastigenic data by skin

in vivo

Elcatonin (Carbocalcitonin) (20 U/kg; s.c.; 2 d after oxaliplatin administration) attenuats oxaliplatin-induced cold and mechanical allodynia in rats[2].

Animal Model:Male Sprague-Dawley rats weighing 150-250 g (Oxaliplatin-Induced Allodynia Models)[1]
Dosage:20 U/kg
Administration:Subcutaneously; 2 d after oxaliplatin administration
Result:Attenuated oxaliplatin-induced cold in rtas.

Description

Elcatonin Synthetic is a single, non-glycosylated polypeptide chain containing 31 amino acids, having a molecular mass of 3363.2 Dalton and a Molecular formula of C148H244N42O47.

Background

Elcatonin is a Calcitonin derivative which is transformed from eel´s calcitonin by changing the S-S bond into the stable C-N bond. It inhibits the absorption and autolysis of bones, thus leads to blood calcium descending. In addition, it inhibits the bone salts dissolving and transferring and promotes the excretion of calcium and phosphorus in urine. Meanwhile, it inhibits renal tubules reabsorbing calcium, phosphorus and sodium and keeps blood calcium at normal level. It is mainly used for remitting or eliminating the pain caused by Osteoporosis.

Elcatonin Preparation Products And Raw materials

Raw materials

Preparation Products

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Elcatonin Suppliers

China 170 Europe 2 Germany 2 India 1 Japan 1 Switzerland 1 United Kingdom 5 United States 16 Global 198
Adachibio Inc.
Tel
+81-8027837258; +8108027837258
Fax
0081-80278372055
Email
sales@adachibio.com
Country
Japan
ProdList
992
Advantage
58
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View Lastest Price from Elcatonin manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
Elcatonin 60731-46-6
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10000KGS
Release date
2025-05-19
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Elcatonin 60731-46-6
Price
US $0.00/g
Min. Order
1g
Purity
98%min
Supply Ability
1000g
Release date
2023-01-12
Shaanxi Dideu New Materials Co. Ltd
Product
Elcatonin 60731-46-6
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000KGS
Release date
2025-02-26

60731-46-6, ElcatoninRelated Search:

Viaminate Torasemide Penicillin G potassium salt Zoledronic acid Rituximab Ribonucleic acid Alendronate sodium Glucosamine sulfate Calcitriol Calcitonin salmon Calcitonin OXYTOCIN/DESMOPRESSIN VALIDATION MIXTURE Calcitonin eel Calcitonin [Asu1,7] (eel) (Carbacalcitonin, Elcatonin) Elcatonin ELCATONIN = CARBOCALCITONIN ELCATONIN,RABBITANTI-:RIA ANTI-ELCATONIN

  • (aminosubericacid1,7)-eelcalcitonin
  • 1-butanoicacid-26-l-asparticacid-27-l-valine-7-dicarbacalcitonin(salmon)
  • 29-l-alanine-
  • (L-ALPHA-AMINOSUBERIC ACID1,7)-CALCITONIN (EEL)
  • ELCATONIN
  • ELCATONIN (EEL)
  • (DES CYS1,CYCLO (SER2-ASU7))-CALCITONIN (EEL) ACETATE SALT
  • CYCLO(-SER-ASN-LEU-SER-THR-ASU)-VAL-LEU-GLY-LYS-LEU-SER-GLN-GLU-LEU-HIS-LYS-LEU-GLN-THR-TYR-PRO-ARG-THR-ASP-VAL-GLY-ALA-GLY-THR-PRO-NH2
  • CARBACALCITONIN (EEL)
  • CARBOCALCITONIN
  • (ASU1'7)-CALCITONIN (EEL)
  • [ASU1,7]-CALCITONIN (EEL)
  • (ASU1,7)-CALCITONIN (EEL) ACETATE SALT
  • Elcatonin Acetate
  • ELCATONIN, 98.0+%
  • Cyclo(-Ser-Asn-Leu-Ser-Thr-Asu)-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asp-Val-Gly-Ala-Gly-Thr-Pro-NH2 acetate salt
  • hc-58
  • Ser-Asn-Leu-Ser-Thr-Asu-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asp-Val-Gly-Ala-Thr-Pro-NH2 cyclic (1-6)
  • 1,7-DICARBACALCITONIN, 1-BUTANOIC ACID-
  • SER-ASN-LEU-SER-THR-ASU-VAL-LEU-GLY-LYS-LEU-SER-GLN-GLU-LEU-HIS-LYS-LEU-GLN-THR-TYR-PRO-ARG-THR-ASP-VAL-GLY-ALA-GLY-THR-PRO-NH2: SNLST-ASU-VLGKLSQELHKLQTYPRTDVGAGTP-NH2
  • SER-ASN-LEU-SER-THR-ASU-VAL-LEU-GLY-LYS-LEU-SER-GLN-GLU-LEU-HIS-LYS-LEU-GLN-THR-TYR-PRO-ARG-THR-ASP-VAL-GLY-ALA-GLY-THR-PRO (LACTAM BRIDGE: SER1-ASU6)
  • Elcatonin, (Asu1·7)-Calcitonin (eel)
  • 1,7-Dicarbacalcitonin(eel), 1-butanoic acid- (9CI)
  • Ser-Asn-Leu-Ser-Thr-Asu-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asp-Val-Gly-Ala-Gly-Thr-Pro (Ser----Asu)
  • Des-Cys1,cyclo(Ser2-Asu7))-Calcitonin (eel), Elcatonin, (Asu17)-Calcitonin (eel)
  • Elcatonin RS
  • L-Prolinamide, L-seryl-L-asparaginyl-L-leucyl-L-seryl-L-threonyl-(2S)-2-amino-7-carboxyheptanoyl-L-valyl-L-leucylglycyl-L-lysyl-L-leucyl-L-seryl-L-glutaminyl-L-α-glutamyl-L-leucyl-L-histidyl-L-lysyl-L-leucyl-L-glutaminyl-L-threonyl-L-tyrosyl-L-prolyl-L-arginyl-L-threonyl-L-α-aspartyl-L-valylglycyl-L...
  • Elcatonin USP/EP/BP
  • (Des-Cys?,cyclo(Ser?-Asu?))-Calcitonin (eel) acetate salt
  • Edoxaban Impurity 20 Toluenesulfonate
  • 60731-46-6
  • C148H244N42O47