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Methyl L-lysinate dihydrochloride

Product Name
Methyl L-lysinate dihydrochloride
CAS No.
26348-70-9
Chemical Name
Methyl L-lysinate dihydrochloride
Synonyms
H-LYS-OME;LYS.OME.2HCL;H-LYS-OME 2HCL;L-Lys-OMe 2HCl;LYSINE-OME 2 HCL;H-L-Lys-OMe*2HCl;Methyl L-lysinate di;L-Lysine Methyl Ester 2HCl;H-Lys-OMe. Dihydrochloride;L-LYSINE METHYL ESTER DIHCL
CBNumber
CB6483290
Molecular Formula
C7H18Cl2N2O2
Formula Weight
233.14
MOL File
26348-70-9.mol
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Methyl L-lysinate dihydrochloride Property

Melting point:
213-215°C
refractive index 
17 ° (C=5, H2O)
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
Methanol, Water
form 
Crystalline Powder
color 
White
Water Solubility 
Soluble in water.
Sensitive 
Hygroscopic
BRN 
5302183
CAS DataBase Reference
26348-70-9(CAS DataBase Reference)
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Safety

Risk Statements 
36/37/38
Safety Statements 
26-36/37/39-24/25
WGK Germany 
3
HS Code 
29224190
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

H335May cause respiratory irritation

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P363Wash contaminated clothing before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
L0645
Product name
L-Lysine methyl ester dihydrochloride
Packaging
5g
Price
$113
Updated
2025/07/31
Sigma-Aldrich
Product number
L0645
Product name
L-Lysine methyl ester dihydrochloride
Packaging
25g
Price
$398
Updated
2023/01/07
TCI Chemical
Product number
L0202
Product name
L-Lysine Methyl Ester Dihydrochloride
Purity
>98.0%(N)
Packaging
5g
Price
$27
Updated
2025/07/31
TCI Chemical
Product number
L0202
Product name
L-Lysine Methyl Ester Dihydrochloride
Purity
>98.0%(N)
Packaging
25g
Price
$108
Updated
2025/07/31
TRC
Product number
L468900
Product name
L-Lysine Methyl Ester Dihydrochloride
Packaging
100g
Price
$495
Updated
2021/12/16
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Methyl L-lysinate dihydrochloride Chemical Properties,Usage,Production

Chemical Properties

Light Yellow Solid

Uses

L-Lysine methyl ester dihydrochloride is used in the production of lysine methyl ester based cationic surfactants and hydrogels.

Uses

Methyl L-lysinate dihydrochloride can be used in the synthesis of peptides containing histidine and lysine.

Synthesis

67-56-1

657-27-2

13515-95-2

L-lysine hydrochloride (2,5.00 g, 27.4 mmol, 1.0 equiv) and methanol (30 mL, 0.9 M) were added to a round bottom flask. The suspension was heated to reflux until the solid was completely dissolved. Thionyl chloride (2.59 mL, 35.6 mmol, 1.3 eq.) was added slowly dropwise with a controlled drip time of 15 minutes. The reaction system was kept under reflux conditions for 17 hours. Upon completion of the reaction, most of the volatiles were removed by distillation (ca. 25 mL), followed by azeotropy with toluene under reduced pressure to remove the remaining volatiles to afford pure lysine methyl ester dihydrochloride (3, quantitative yield, white solid), which was used directly in the next step of the reaction without further purification. The physical and chemical properties of the resulting compound were analyzed to be consistent with the data reported in the literature.

References

[1] Tetrahedron Letters, 2016, vol. 57, # 4, p. 502 - 504
[2] Journal of Medicinal Chemistry, 2002, vol. 45, # 17, p. 3669 - 3683
[3] Heterocycles, 2017, vol. 94, # 5, p. 964 - 978
[4] Journal of Polymer Science, Part A: Polymer Chemistry, 2015, vol. 53, # 17, p. 2036 - 2049
[5] Molecules, 2016, vol. 21, # 1,

Methyl L-lysinate dihydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Methyl L-lysinate dihydrochloride Suppliers

J & K SCIENTIFIC LTD.
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18210857532; 18210857532
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86-10-82849933
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jkinfo@jkchemical.com
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China
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96815
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Meryer (Shanghai) Chemical Technology Co., Ltd.
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021-61259138 18621169109
Fax
86-21-61259102
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market03@meryer.com
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China
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Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
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China
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TAIYUAN RHF CO.,LTD.
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+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
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TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
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Sales-CN@TCIchemicals.com
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China
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Energy Chemical
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021-021-58432009 400-005-6266
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GL Biochem (Shanghai) Ltd
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86-21-61263399
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ymbetter@glbiochem.com
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China
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Capot Chemical Co., Ltd
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+86 (0) 571 85 58 67 18
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0086-571-85864795
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sales@capotchem.com
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China
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Beijing Ouhe Technology Co., Ltd
Tel
010-010-82967028 13522913783
Fax
+86-10-82967029
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2355560935@qq.com
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China
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Shanghai Hanhong Scientific Co.,Ltd.
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021-54306202 13764082696
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info@hanhongsci.com
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China
ProdList
42934
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View Lastest Price from Methyl L-lysinate dihydrochloride manufacturers

Career Henan Chemical Co
Product
Methyl L-lysinate dihydrochloride 26348-70-9
Price
US $100.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
Customized
Release date
2018-07-30

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  • Amino Acids & Derivatives
  • Lysine [Lys, K]
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