DIPHENYLAMINE HYDROCHLORIDE
- Product Name
- DIPHENYLAMINE HYDROCHLORIDE
- CAS No.
- 537-67-7
- Chemical Name
- DIPHENYLAMINE HYDROCHLORIDE
- Synonyms
- DiphenylamineHCl;diphenylammonium chloride;DIPHENYLAMINE HYDROCHLORIDE;DiphenylaMine Hydrochlori...;N-PHENYLANILINE HYDROCHLORIDE;Diphenylamine Hydrochloride >Diphenylamine hydrochloride,99%;n-phenyl-benzenaminhydrochloride;Diphenylamine hydrochloride,≥99.0%;Benzenamine, N-phenyl-,hydrochloride (1:1)
- CBNumber
- CB1278532
- Molecular Formula
- C12H12ClN
- Formula Weight
- 205.68
- MOL File
- 537-67-7.mol
DIPHENYLAMINE HYDROCHLORIDE Property
- Melting point:
- 180 °C
- storage temp.
- <0°C
- form
- powder to crystal
- color
- White to Almost white
- InChIKey
- JEFJSEIUEJBMSR-UHFFFAOYSA-N
- CAS DataBase Reference
- 537-67-7(CAS DataBase Reference)
- EPA Substance Registry System
- Benzenamine, N-phenyl-, hydrochloride (537-67-7)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- D0874
- Product name
- Diphenylamine Hydrochloride
- Purity
- >99.0%(HPLC)(N)
- Packaging
- 25g
- Price
- $52
- Updated
- 2025/07/31
- Product number
- D492845
- Product name
- Diphenylamine Hydrochloride
- Packaging
- 500mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- D492845
- Product name
- Diphenylamine Hydrochloride
- Packaging
- 2.5g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 7678AB
- Product name
- Diphenylamine Hydrochloride
- Packaging
- 25g
- Price
- $116
- Updated
- 2021/12/16
- Product number
- 537677
- Product name
- Diphenylamine Hydrochloride
- Packaging
- 500g
- Price
- $439.04
- Updated
- 2021/12/16
DIPHENYLAMINE HYDROCHLORIDE Chemical Properties,Usage,Production
Chemical Properties
white crystalline powder
Uses
Diphenylamine hydrochloride (N-Phenylaniline hydrochloride) is an antihyperglycemic agent with oral activity and a common structure in non-steroidal anti-inflammatory drugs (NSAIDs) that uncouples oxidative phosphorylation in mitochondria, leading to a decrease in hepatic cell ATP levels and causing liver cell damage. Diphenylamine hydrochloride is also an industrial antioxidant, a dyeing mordant, and is used in agriculture as an antifungal and antibacterial agent[1][2][3][4].
in vivo
Diphenylamine hydrochloride is excreted in rats through urine and bile[1].
Diphenylamine (10 mg/kg, orally, single dose) hydrochloride lowers blood sugar in hyperglycemic rabbits[2].
| Animal Model: | Hyperglycemic rabbit[2] |
| Dosage: | 10 mg/kg; single dose |
| Administration: | Oral |
| Result: | Reduced blood sugar by 61.4% two hours after administration. |
References
[1] W E Alexander, et al. Metabolism of diphenylamine in the rat, rabbit and man. Food Cosmet Toxicol. 1965 Oct;3(4):571-9. DOI:10.1016/s0015-6264(65)80203-6
[2] M S Karawya, wt al. Diphenylamine, an antihyperglycemic agent from onion and tea. J Nat Prod. 1984 Sep-Oct;47(5):775-80. DOI:10.1021/np50035a003
[3] Safe S, et al. Identification of toxic impurities in commercial diphenylamine. Bull Environ Contam Toxicol. 1977 Feb;17(2):204-7. DOI:10.1007/BF01685551
[4] Masubuchi Y, et al. Possible mechanism of hepatocyte injury induced by diphenylamine and its structurally related nonsteroidal anti-inflammatory drugs. J Pharmacol Exp Ther. 2000 Mar;292(3):982-7. PMID:10688613
DIPHENYLAMINE HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from DIPHENYLAMINE HYDROCHLORIDE manufacturers
- Product
- DIPHENYLAMINE HYDROCHLORIDE 537-67-7
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11