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DIPHENYLAMINE HYDROCHLORIDE

Product Name
DIPHENYLAMINE HYDROCHLORIDE
CAS No.
537-67-7
Chemical Name
DIPHENYLAMINE HYDROCHLORIDE
Synonyms
DiphenylamineHCl;diphenylammonium chloride;DIPHENYLAMINE HYDROCHLORIDE;DiphenylaMine Hydrochlori...;N-PHENYLANILINE HYDROCHLORIDE;Diphenylamine Hydrochloride >Diphenylamine hydrochloride,99%;n-phenyl-benzenaminhydrochloride;Diphenylamine hydrochloride,≥99.0%;Benzenamine, N-phenyl-,hydrochloride (1:1)
CBNumber
CB1278532
Molecular Formula
C12H12ClN
Formula Weight
205.68
MOL File
537-67-7.mol
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DIPHENYLAMINE HYDROCHLORIDE Property

Melting point:
180 °C
storage temp. 
<0°C
form 
powder to crystal
color 
White to Almost white
InChIKey
JEFJSEIUEJBMSR-UHFFFAOYSA-N
CAS DataBase Reference
537-67-7(CAS DataBase Reference)
EPA Substance Registry System
Benzenamine, N-phenyl-, hydrochloride (537-67-7)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
37/39-26
HS Code 
2921.44.7000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
D0874
Product name
Diphenylamine Hydrochloride
Purity
>99.0%(HPLC)(N)
Packaging
25g
Price
$52
Updated
2025/07/31
TRC
Product number
D492845
Product name
Diphenylamine Hydrochloride
Packaging
500mg
Price
$60
Updated
2021/12/16
TRC
Product number
D492845
Product name
Diphenylamine Hydrochloride
Packaging
2.5g
Price
$75
Updated
2021/12/16
AK Scientific
Product number
7678AB
Product name
Diphenylamine Hydrochloride
Packaging
25g
Price
$116
Updated
2021/12/16
Alichem
Product number
537677
Product name
Diphenylamine Hydrochloride
Packaging
500g
Price
$439.04
Updated
2021/12/16
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DIPHENYLAMINE HYDROCHLORIDE Chemical Properties,Usage,Production

Chemical Properties

white crystalline powder

Uses

Diphenylamine hydrochloride (N-Phenylaniline hydrochloride) is an antihyperglycemic agent with oral activity and a common structure in non-steroidal anti-inflammatory drugs (NSAIDs) that uncouples oxidative phosphorylation in mitochondria, leading to a decrease in hepatic cell ATP levels and causing liver cell damage. Diphenylamine hydrochloride is also an industrial antioxidant, a dyeing mordant, and is used in agriculture as an antifungal and antibacterial agent[1][2][3][4].

in vivo

Diphenylamine hydrochloride is excreted in rats through urine and bile[1].
Diphenylamine (10 mg/kg, orally, single dose) hydrochloride lowers blood sugar in hyperglycemic rabbits[2].

Animal Model:Hyperglycemic rabbit[2]
Dosage:10 mg/kg; single dose
Administration:Oral
Result:Reduced blood sugar by 61.4% two hours after administration.

References

[1] W E Alexander, et al. Metabolism of diphenylamine in the rat, rabbit and man. Food Cosmet Toxicol. 1965 Oct;3(4):571-9. DOI:10.1016/s0015-6264(65)80203-6
[2] M S Karawya, wt al. Diphenylamine, an antihyperglycemic agent from onion and tea. J Nat Prod. 1984 Sep-Oct;47(5):775-80. DOI:10.1021/np50035a003
[3] Safe S, et al. Identification of toxic impurities in commercial diphenylamine. Bull Environ Contam Toxicol. 1977 Feb;17(2):204-7. DOI:10.1007/BF01685551
[4] Masubuchi Y, et al. Possible mechanism of hepatocyte injury induced by diphenylamine and its structurally related nonsteroidal anti-inflammatory drugs. J Pharmacol Exp Ther. 2000 Mar;292(3):982-7. PMID:10688613

DIPHENYLAMINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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DIPHENYLAMINE HYDROCHLORIDE Suppliers

J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
PharmaBlock Sciences (Nanjing),Inc.
Tel
025-86918202 4000255188
Fax
86-025-86918232
Email
sales@pharmablock.com
Country
China
ProdList
5000
Advantage
55
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9815
Advantage
79
T&W GROUP
Tel
021-61551611 13296011611
Fax
+86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9895
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19913
Advantage
55
TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
Advantage
80
TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
ProdList
23671
Advantage
75
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View Lastest Price from DIPHENYLAMINE HYDROCHLORIDE manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
DIPHENYLAMINE HYDROCHLORIDE 537-67-7
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11

537-67-7, DIPHENYLAMINE HYDROCHLORIDERelated Search:


  • N-PHENYLANILINE HYDROCHLORIDE
  • Diphenylamine hydrochloride,99%
  • DiphenylaMine Hydrochlori...
  • DIPHENYLAMINE HYDROCHLORIDE
  • n-phenyl-benzenaminhydrochloride
  • diphenylammonium chloride
  • DiphenylamineHCl
  • 2-propenoic acid 1,2,3,4,4a,5,6,7,8,8a-decahydronaphthalen-2-yl ester
  • Diphenylamine Hydrochloride &gt
  • DIPHENYLAMINE HYDROCHLORIDE ISO 9001:2015 REACH
  • Diphenylamine hydrochloride,≥99.0%
  • Benzenamine, N-phenyl-,hydrochloride (1:1)
  • Diphenylamine Hydrochloride, 10 mM in DMSO
  • 537-67-7
  • C12H11NHCl
  • C12H11NHCI