ChemicalBook > CAS DataBase List > 2-Chloro-1,3,2-dioxaphospholane

2-Chloro-1,3,2-dioxaphospholane

Product Name
2-Chloro-1,3,2-dioxaphospholane
CAS No.
822-39-9
Chemical Name
2-Chloro-1,3,2-dioxaphospholane
Synonyms
AURORA KA-1222;Ethyl chlorphosphite;ETHYLENE CHLOROPHOSPHITE;Ethylenechlorophosphite,97%;Ethylenephosphorochloridite;ETHYLENE CYCL-CHLOROPHOSPHITE;2-dioxaphospholane,2-chloro-3;ETHYLENE CYCLO-CHLOROPHOSPHITE;2-CHLORO-1,3,2-DIOXAPHOSPHOLANE;Ethylene glycol chlorophosphite
CBNumber
CB6494609
Molecular Formula
C2H4ClO2P
Formula Weight
126.48
MOL File
822-39-9.mol
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2-Chloro-1,3,2-dioxaphospholane Property

Melting point:
-28°C(lit.)
Boiling point:
62 °C/20 mmHg (lit.)
Density 
1.422 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.489(lit.)
Flash point:
158 °F
storage temp. 
2-8°C
solubility 
Chloroform (Slightly)
form 
clear liquid
color 
Colorless to Light yellow
Sensitive 
Moisture Sensitive
BRN 
506179
Stability:
Extremely Moisture Sensitive
CAS DataBase Reference
822-39-9(CAS DataBase Reference)
NIST Chemistry Reference
Ethylene chlorophosphite(822-39-9)
EPA Substance Registry System
1,3,2-Dioxaphospholane, 2-chloro- (822-39-9)
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Safety

Hazard Codes 
C
Risk Statements 
14-34-37
Safety Statements 
26-36/37/39-45-8-25
RIDADR 
UN 3264 8/PG 2
WGK Germany 
3
F 
1-10
Hazard Note 
Highly reactive cyclic phosphitylating reagent which
TSCA 
Yes
HS Code 
2934.99.9001
HazardClass 
8
PackingGroup 
II
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
391220
Product name
2-Chloro-1,3,2-dioxaphospholane
Purity
97%
Packaging
5ml
Price
$167
Updated
2025/07/31
TCI Chemical
Product number
C1215
Product name
2-Chloro-1,3,2-dioxaphospholane
Purity
>97.0%(GC)
Packaging
5g
Price
$37
Updated
2025/07/31
TCI Chemical
Product number
C1215
Product name
2-Chloro-1,3,2-dioxaphospholane
Purity
>97.0%(GC)
Packaging
25g
Price
$109
Updated
2025/07/31
TRC
Product number
C365500
Product name
2-Chloro-1,3,2-dioxaphospholane
Packaging
5g
Price
$60
Updated
2021/12/16
Chem-Impex
Product number
37312
Product name
2-Chloro-1,3,2-dioxaphospholane,97%(GC)
Purity
97%(GC)
Packaging
1G
Price
$16.8
Updated
2021/12/16
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2-Chloro-1,3,2-dioxaphospholane Chemical Properties,Usage,Production

Chemical Properties

Clear Colourless Oil

Uses

Highly reactive cyclic phosphitylating reagent which provides fast coupling rates, and hydrolytic cleavage occurs more readily than with acyclic analogs

Uses

Ethylene chlorophosphite acts as a phosphitylating agent involved in the preparation of phosphocholine and spirophosphoranes. For example, it is used in the phosphorylation of p-tert-butyl(thia)calixarenes.

reaction suitability

reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: ligand

2-Chloro-1,3,2-dioxaphospholane Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Chloro-1,3,2-dioxaphospholane Suppliers

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822-39-9, 2-Chloro-1,3,2-dioxaphospholaneRelated Search:

Ethylene glycol ETHYLENE OXIDE Ethylene carbonate Cyclopentyl chloride Dimethyl phosphite Vinyl acetate ETHYLENE DIACRYLATE Cyclopentane Bromocyclopentane Vinylene carbonate VINYL CHLORIDE 1,2-Dibromoethane Methylcyclopentane POLY(ETHYLENE) Diethylene glycol Epichlorohydrin ETHYLENE Ethylene glycol diacetate

  • 1,3,2-Dioxaphospholane, 2-chloro-
  • 1,3,2-Dioxaphosphorane.2-chloro-
  • 2-dioxaphospholane,2-chloro-3
  • Ethylenephosphorochloridite
  • AURORA KA-1222
  • ETHYLENE CYCL-CHLOROPHOSPHITE
  • ETHYLENE CYCLO-CHLOROPHOSPHITE
  • ETHYLENE CHLOROPHOSPHITE
  • 2-CHLORO-1,3,2-DIOXAPHOSPHOLANE
  • Ethylenechlorophosphite,97%
  • 2-Chloro-1,3,2-dioxaphospholane,97%
  • Ethylene phosphorochloridite（2-chloro-1,3,2-dioxaphospholane)
  • Ethylene glycol chlorophosphite
  • Cyclic O,O-Ethylene Phosphorochloridite
  • Cyclic Phosphorochloridite Ethylene Glycol
  • Phosphorochloridous Acid Cyclic Ethylene Ester
  • Cyclic ethylene chlorophosphite
  • Cyclic ethylene phosphorochloridite
  • 2-Chloro-1,3,2-dioxaphospholane 97%
  • 2-Chloro-1,3,2-dioxaphospholane &gt
  • Ethyl chlorphosphite
  • 822-39-9
  • C2H4ClO2P
  • Phosphorus Compounds
  • Phosphorus Precursors
  • Catalysis and Inorganic Chemistry
  • Phosphorylating Agents
  • DNA / RNA Synthesis
  • Phosphorylation
  • Biochemistry
  • Nucleosides, Nucleotides & Related Reagents
  • Phosphorylating and Phosphorothioating Agents
  • Phosphorylation
  • Protecting Agents, Phosphorylating Agents & Condensing Agents
  • Synthetic Organic Chemistry
  • Phosphorylating and Phosphitylating Agents