2-Chloro-1,3,2-dioxaphospholane Property

Melting point:

-28°C(lit.)

Boiling point:

62 °C/20 mmHg (lit.)

Density 

1.422 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.489(lit.)

Flash point:

158 °F

storage temp. 

2-8°C

solubility 

Chloroform (Slightly)

form 

clear liquid

color 

Colorless to Light yellow

Sensitive 

Moisture Sensitive

BRN 

506179

Stability:

Extremely Moisture Sensitive

CAS DataBase Reference

822-39-9(CAS DataBase Reference)

NIST Chemistry Reference

Ethylene chlorophosphite(822-39-9)

EPA Substance Registry System

1,3,2-Dioxaphospholane, 2-chloro- (822-39-9)

Safety

Hazard Codes 

C

Risk Statements 

14-34-37

Safety Statements 

26-36/37/39-45-8-25

RIDADR 

UN 3264 8/PG 2

WGK Germany 

3

F 

1-10

Hazard Note 

Highly reactive cyclic phosphitylating reagent which

TSCA 

Yes

HS Code 

2934.99.9001

HazardClass 

8

PackingGroup 

II

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

2-Chloro-1,3,2-dioxaphospholane Chemical Properties,Usage,Production

Chemical Properties

Clear Colourless Oil

Uses

Highly reactive cyclic phosphitylating reagent which provides fast coupling rates, and hydrolytic cleavage occurs more readily than with acyclic analogs

Uses

Ethylene chlorophosphite acts as a phosphitylating agent involved in the preparation of phosphocholine and spirophosphoranes. For example, it is used in the phosphorylation of p-tert-butyl(thia)calixarenes.