ChemicalBook > CAS DataBase List > tert-butyl 4-(3-cyano-2-(4-phenoxyphenyl)pyrazolo[1,5-a]pyrimidin-7-yl)piperidine-1-carboxylate
tert-butyl 4-(3-cyano-2-(4-phenoxyphenyl)pyrazolo[1,5-a]pyrimidin-7-yl)piperidine-1-carboxylate
- Product Name
- tert-butyl 4-(3-cyano-2-(4-phenoxyphenyl)pyrazolo[1,5-a]pyrimidin-7-yl)piperidine-1-carboxylate
- CAS No.
- 2190506-55-7
- Chemical Name
- tert-butyl 4-(3-cyano-2-(4-phenoxyphenyl)pyrazolo[1,5-a]pyrimidin-7-yl)piperidine-1-carboxylate
- Synonyms
- Zanubrutinib Impurity 9;Zanubrutinib Impurity 2;Zanubrutinib impurity-18;Zanubrutinib acetyl impurity;tert-butyl 4-(3-cyano-2-(4-phenoxyphenyl)pyrazolo[1,5-a]pyrimidin-7-yl)piperidine-1-carboxylate;7-?(1-?Boc-?4-?piperidyl)?-?2-?(4-?phenoxyphenyl)?pyrazolo[1,?5-?a]?pyrimidine-?3-?carbonitrile;(R)-2-(4-phenoxyphenyl)-7-(piperidin-4-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide;7-(1-acetylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide;tert-butyl 4-(3-cyano-4,5,6,7-tetrahydro-2-(4-phenoxyphenyl)pyrazolo[1,5-a]pyrimidin-7-yl)piperidine-1-carboxylate;1-Piperidinecarboxylic acid, 4-[3-cyano-2-(4-phenoxyphenyl)pyrazolo[1,5-a]pyrimidin-7-yl]-, 1,1-dimethylethyl ester
- CBNumber
- CB65442564
- Molecular Formula
- C29H29N5O3
- Formula Weight
- 495.57
- MOL File
- 2190506-55-7.mol
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tert-butyl 4-(3-cyano-2-(4-phenoxyphenyl)pyrazolo[1,5-a]pyrimidin-7-yl)piperidine-1-carboxylate Property
- Density
- 1.24±0.1 g/cm3(Predicted)
- pka
- -1.43±0.40(Predicted)
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tert-butyl 4-(3-cyano-2-(4-phenoxyphenyl)pyrazolo[1,5-a]pyrimidin-7-yl)piperidine-1-carboxylate Chemical Properties,Usage,Production
Uses
7-?(1-?Boc-?4-?piperidyl)?-?2-?(4-?phenoxyphenyl)?pyrazolo[1,?5-?a]?pyrimidine-?3-?carbonitrile is used as a reagent in the synthesis of Zanubrutinib (BGB-3111), a novel, potent, and selective covalent inhibitor of Bruton''s tyrosine kinase.
tert-butyl 4-(3-cyano-2-(4-phenoxyphenyl)pyrazolo[1,5-a]pyrimidin-7-yl)piperidine-1-carboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
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2190506-55-7, tert-butyl 4-(3-cyano-2-(4-phenoxyphenyl)pyrazolo[1,5-a]pyrimidin-7-yl)piperidine-1-carboxylateRelated Search:
Pyrazolo[1,5-a]pyrimidine-3-carbonitrile, 4,5,6,7-tetrahydro-2-(4-phenoxyphenyl)-7-(4-piperidinyl)-, hydrochloride (1:2), (7S)-
b,b-Carotene-3,3'-diol, 5,8-epoxy-5,8-dihydro-,(3S,3'R,5R)-
Zeaxanthin Impurity 6
Zanubrutinib
Pyrazolo[1,5-a]pyrimidine-3-carbonitrile, 4,5,6,7-tetrahydro-2-(4-phenoxyphenyl)-7-(4-piperidinyl)-
4-PHENOXYBENZOIC ACID
4-Acetyl-piperidine-1-carboxylic acid tert-butyl ester
(R)-Zanubrutinib
Pyrazolo[1,5-a]pyrimidine-3-carboxamide, 4,5,6,7-tetrahydro-2-(4-phenoxyphenyl)-7-(4-piperidinyl)-, (7S)-
5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile
tert-butyl 4-(3-cyano-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-7-yl)piperidine-1-carboxylate
Propanedinitrile, 2-[Methoxy(4-phenoxyphenyl)Methylene]-
Propanedinitrile, 2-[hydroxy(4-phenoxyphenyl)Methylene]-
1-Piperidinecarboxylic acid, 4-[3-(dimethylamino)-1-oxo-2-propen-1-yl]-, 1,1-dim