Thalidomide-NH-C4-NH2 TFA

Product Name: Thalidomide-NH-C4-NH2 TFA
CAS No.: 2093387-50-7
Chemical Name: Thalidomide-NH-C4-NH2 TFA
Synonyms: Poma-C4-NH2 TFA;Pomalidomide-C4-NH2 TFA;halidomide-NH-C4-NH2TFA;Thalidomide-NH-C4-NH2 TFA;Pomalidomide Related Compound 10 Triflate;4-((4-aminobutyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione 2,2,2-trifluoroacetate
CBNumber: CB66127051
Molecular Formula: C19H21F3N4O6
Formula Weight: 458.39
MOL File: 2093387-50-7.mol

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Hazard and Precautionary Statements (GHS)

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Thalidomide-NH-C4-NH2 TFA Chemical Properties,Usage,Production

Biological Activity

Thalidomide-NH-C4-NH2 TFA (compound 29c) is an E3 ligase ligand-linker conjugate, and incorporates the Thalidomide based cereblon ligand and a linker. Thalidomide-NH-C4-NH2 TFA is used in PROTAC BRD2/BRD4 degrader-1 . PROTAC BRD2/BRD4 degrader-1 is a potent and selective BET protein BRD4 and BRD2 degrader[1].

References

[1]. Jiang F, et al. Discovery of novel small molecule induced selective degradation of the bromodomain and extra-terminal (BET) bromodomain protein BRD4 and BRD2 with cellular potencies. Bioorg Med Chem. 2020 Jan 1;28(1):115181.

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View Lastest Price from Thalidomide-NH-C4-NH2 TFA manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Pomalidomide-C4-NH2 TFA 2093387-50-7
Price: US $0.00/mg
Min. Order: 100mg
Purity: >99.00%
Supply Ability: 100mg
Release date: 2024-04-01

2093387-50-7, Thalidomide-NH-C4-NH2 TFARelated Search:

Thalidomide-linker 6 Thalidomide-C2-amido-C2-COOH Thalidomide-NH-C6-NH2 TFA Thalidomide-NH-PEG2-C2-NH2 hydrochloride Thalidomide-NH-PEG2-C2-NH2 (TFA) Thalidomide-NH-C4-NH-Boc Undecanoic acid, 11-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- -alkylC5-amine

Thalidomide-NH-C4-NH2 TFA

Pomalidomide Related Compound 10 Triflate

4-((4-aminobutyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione 2,2,2-trifluoroacetate

halidomide-NH-C4-NH2TFA

Pomalidomide-C4-NH2 TFA

Poma-C4-NH2 TFA

2093387-50-7