Thalidomide-NH-PEG2-C2-NH2 (TFA)

Product Name: Thalidomide-NH-PEG2-C2-NH2 (TFA)
CAS No.: 2097509-36-7
Chemical Name: Thalidomide-NH-PEG2-C2-NH2 (TFA)
Synonyms: Thalidomide-NH-PEG2-NH2 TFA;Thalidomide-4-NH-PEG2-NH2 TFA;Thalidomide-PEG2-C2-NH2 (TFA);Thalidomide-NH-PEG2-C2-NH2 (TFA);4-[2-[2-(2-aminoethoxy)ethoxy]ethylamino]-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione;4-((2-(2-(2-aminoethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione 2,2,2-trifluoroacetate
CBNumber: CB05848939
Molecular Formula: C21H25F3N4O8
Formula Weight: 518.45
MOL File: 2097509-36-7.mol

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Thalidomide-NH-PEG2-C2-NH2 (TFA) Property

form: Solid
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

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Thalidomide-NH-PEG2-C2-NH2 (TFA) Chemical Properties,Usage,Production

Uses

Thalidomide-PEG2-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology[1].

IC 50

Cereblon

References

[1] Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Sep 12;62(17):8152-8163. DOI:10.1021/acs.jmedchem.9b00919

Thalidomide-NH-PEG2-C2-NH2 (TFA) Preparation Products And Raw materials

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Preparation Products

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Thalidomide-NH-PEG2-C2-NH2 (TFA) Suppliers

China 14 United States 2 Global 16

Sichuan Wei Keqi Biological Technology Co., Ltd.

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Jilin Province Woda Biotechnology Co., Ltd.

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CR Corporation Limited

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TargetMol Chemicals Inc.

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Shanghai Kaiwei Chemical Technology Co., Ltd.

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Zhengzhou Convergence Chemical Co. LTD

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Shanghai Haohong Pharmaceutical Co., Ltd.

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Xi'an Qiyue Biotechnology Co., Ltd.

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Yutong Pharmaceutical Technology (Suzhou) Co., Ltd.

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Chengdu Yuxin Technology Co., Ltd.

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2097509-36-7, Thalidomide-NH-PEG2-C2-NH2 (TFA)Related Search:

Thalidomide-O-amido-C2-NH2 4-((2-(2-(2-aminoethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione 2-(2,6-dioxopiperidin-3-yl)-4-(prop-2-yn-1-yloxy)isoindoline-1,3-dione -alkylC5-amine 4-[(6-Aminohexyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl E3 ligase Ligand-Linker Conjugates 15 Thalidomide-O-amido-C2-NH2 Thalidomide-NH-C4-NH-Boc Thalidomide-NH-C6-NH2 TFA Thalidomide-NH-C4-NH2 TFA Thalidomide-NH-PEG2-C2-NH2 hydrochloride 5-[[2-(2-aminoethoxy)ethyl]amino]-2-(2,6-dioxo-3-piperidinyl)-1H-Isoindole-1,3(2H)-dione, Pentanoic acid, 5-[[2-(2,6-dioxo-3-piperidinyl)- 2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]amino]- 1H-Isoindole-1,3(2H)-dione, 4-(3-aminopropoxy)-2-(2,6-dioxo-3-piperidinyl)- 5-[(8-aminobutyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-Isoindole-1,3(2H)-dione, 1H-Isoindole-1,3(2H)-dione, 4-(2-aminoethoxy)-2-(2,6-dioxo-3-piperidinyl)- β-Alanine, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]- 5-[(5-aminobutyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-Isoindole-1,3(2H)-dione,

Thalidomide-NH-PEG2-C2-NH2 (TFA)

Thalidomide-PEG2-C2-NH2 (TFA)

Thalidomide-NH-PEG2-NH2 TFA

Thalidomide-4-NH-PEG2-NH2 TFA

4-[2-[2-(2-aminoethoxy)ethoxy]ethylamino]-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione

4-((2-(2-(2-aminoethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione 2,2,2-trifluoroacetate

2097509-36-7